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7ZV5
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BU of 7zv5 by Molmil
Crystal structure of SARS Cov-2 main protease in complex with an inhibitor 4
Descriptor: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, inhibitor TRIP5
Authors:Rahimova, R, Di Micco, S, Marquez, J.A.
Deposit date:2022-05-13
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2.
Eur.J.Med.Chem., 244, 2022
5ARI
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BU of 5ari by Molmil
Bovine mitochondrial ATP synthase state 2b
Descriptor: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
Authors:Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
Deposit date:2015-09-24
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
4ZI5
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BU of 4zi5 by Molmil
Crystal Structure of Dienelactone Hydrolase-like Promiscuous Phospotriesterase P91 from Metagenomic Libraries
Descriptor: CHLORIDE ION, MAGNESIUM ION, P91
Authors:Colin, P.-Y, Fischer, G, Hyvonen, M, Hollfelder, F.
Deposit date:2015-04-27
Release date:2016-02-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics.
Nat Commun, 6, 2015
5IY7
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BU of 5iy7 by Molmil
Human holo-PIC in the open state
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
4IB0
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BU of 4ib0 by Molmil
X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Gerlits, O, Kovalevsky, A.
Deposit date:2012-12-07
Release date:2013-12-11
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
8HNE
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BU of 8hne by Molmil
Crystal structure of the ancestral GH19 chitinase Anc4
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Anc4, ...
Authors:Kozome, D, Laurino, P.
Deposit date:2022-12-07
Release date:2023-12-13
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site.
Nat Commun, 15, 2024
8HNF
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BU of 8hnf by Molmil
Crystal structure of the ancestral GH19 chitinase Anc5
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Anc5, ...
Authors:Kozome, D, Laurino, P.
Deposit date:2022-12-07
Release date:2023-12-13
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site.
Nat Commun, 15, 2024
3M8S
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BU of 3m8s by Molmil
Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-methylated dTTP
Descriptor: 4'-methylthymidine 5'-(tetrahydrogen triphosphate), ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Diederichs, K, Marx, A, Betz, K.
Deposit date:2010-03-19
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA polymerases caught processing size-augmented nucleotide probes.
Angew.Chem.Int.Ed.Engl., 49, 2010
1HJC
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BU of 1hjc by Molmil
CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Descriptor: DNA (5'-(*GP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP* TP*TP*GP*CP*G)-3'), DNA (5'-(CP*CP*GP*CP*AP*AP*CP*CP*AP*CP*AP* GP*AP*GP*TP*T)-3'), RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2001-01-11
Release date:2001-03-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta
Cell(Cambridge,Mass.), 104, 2001
5ARE
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BU of 5are by Molmil
Bovine mitochondrial ATP synthase state 1b
Descriptor: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
Authors:Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
Deposit date:2015-09-24
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
3KHU
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BU of 3khu by Molmil
Crystal structure of human UDP-glucose dehydrogenase Glu161Gln, in complex with thiohemiacetal intermediate
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, UDP-glucose 6-dehydrogenase, ...
Authors:Chaikuad, A, Egger, S, Yue, W.W, Guo, K, Sethi, R, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Kavanagh, K.L, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2009-10-30
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Evidence That Catalytic Reaction of Human UDP-glucose 6-Dehydrogenase Involves Covalent Thiohemiacetal and Thioester Enzyme Intermediates.
J.Biol.Chem., 287, 2012
3M8R
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BU of 3m8r by Molmil
Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-ethylated dTTP
Descriptor: 4'-ethylthymidine 5'-(tetrahydrogen triphosphate), ACETATE ION, DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Diederichs, K, Marx, A, Betz, K.
Deposit date:2010-03-19
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA polymerases caught processing size-augmented nucleotide probes.
Angew.Chem.Int.Ed.Engl., 49, 2010
7LIX
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BU of 7lix by Molmil
CaRSP1 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum
Descriptor: B-phycoerythrin beta chain, CaRSP1, PHYCOERYTHROBILIN
Authors:Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
Deposit date:2021-01-28
Release date:2021-04-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
4EHP
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BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Descriptor: ACETATE ION, Catenin alpha-1, Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-04-03
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
7LIZ
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BU of 7liz by Molmil
LR6 rod linker and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum
Descriptor: B-phycoerythrin beta chain, LR6, PHYCOERYTHROBILIN
Authors:Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
Deposit date:2021-01-28
Release date:2021-04-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
7LJ0
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BU of 7lj0 by Molmil
Linker 3 and scaffolded phycoerythrin beta subunit from the phycobilisome of Porphyridium purpureum
Descriptor: B-phycoerythrin beta chain, Linker 3, PHYCOERYTHROBILIN
Authors:Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
Deposit date:2021-01-28
Release date:2021-04-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
5CB1
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BU of 5cb1 by Molmil
Apo enzyme of human Polymerase lambda
Descriptor: DNA polymerase lambda
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-06-30
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
7LIY
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BU of 7liy by Molmil
CaRSP2 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum
Descriptor: B-phycoerythrin beta chain, CaRSP2, PHYCOERYTHROBILIN
Authors:Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G.
Deposit date:2021-01-28
Release date:2021-04-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
4BER
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BU of 4ber by Molmil
Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
Authors:Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J.
Deposit date:2013-03-12
Release date:2013-04-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
4BET
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BU of 4bet by Molmil
Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein (inactive H229A mutant) in complex with cytidine-diphosphate-choline
Descriptor: GLYCEROL, PHOSPHOCHOLINE TRANSFERASE ANKX, SULFATE ION, ...
Authors:Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J.
Deposit date:2013-03-12
Release date:2013-04-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
4CBU
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BU of 4cbu by Molmil
Crystal structure of Plasmodium falciparum actin I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-1, CALCIUM ION, ...
Authors:Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I.
Deposit date:2013-10-16
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Differences Explain Diverse Functions of Plasmodium Actins.
Plos Pathog., 10, 2014
4IB3
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BU of 4ib3 by Molmil
Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal
Descriptor: ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20
Authors:Gerlits, O, Kovalevsky, A.
Deposit date:2012-12-07
Release date:2013-12-11
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
4IB1
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BU of 4ib1 by Molmil
Structure of cAMP dependent protein kinase A in complex with high K+ concentration, ADP and phosphorylated peptide pSP20
Descriptor: ADENOSINE-5'-DIPHOSPHATE, POTASSIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Gerlits, O, Kovalevsky, A.
Deposit date:2012-12-07
Release date:2013-12-11
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
4LAD
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BU of 4lad by Molmil
Crystal Structure of the Ube2g2:RING-G2BR complex
Descriptor: E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ...
Authors:Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X.
Deposit date:2013-06-19
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
2CAS
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BU of 2cas by Molmil
THE CANINE PARVOVIRUS EMPTY CAPSID STRUCTURE
Descriptor: CANINE PARVOVIRUS EMPTY CAPSID (STRAIN D) VIRAL PROTEIN 2
Authors:Wu, H, Rossmann, M.G.
Deposit date:1993-08-24
Release date:1994-01-31
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:The canine parvovirus empty capsid structure.
J.Mol.Biol., 233, 1993

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数据于2024-09-11公开中

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