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1RAJ
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BU of 1raj by Molmil
Poliovirus Polymerase with a 68 residue N-terminal truncation
Descriptor: Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
7YZC
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BU of 7yzc by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTTTATT site
Descriptor: ACETATE ION, DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZ7
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BU of 7yz7 by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTGGATT site
Descriptor: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*T)-3'), Forkhead box protein H1, ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-18
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZB
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BU of 7yzb by Molmil
Crystal structure of the human FoxH1 bound to the TGTGGATT site
Descriptor: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*T)-3'), Forkhead box protein H1, ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZD
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BU of 7yzd by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTTTACT site (fkh motif GTAAACA)
Descriptor: ACETATE ION, DNA (5'-D(*TP*CP*TP*CP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), DNA (5'-D(P*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*GP*AP*GP*A)-3'), ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZG
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BU of 7yzg by Molmil
Crystal structure of the Xenopus FoxH1 bound to the TGTGGATT site
Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*TP*G)-3'), Forkhead box protein H1
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZE
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BU of 7yze by Molmil
Crystal structure of the human FoxA2 bound to the TGTTTACT site (forkhead motif GTAAACA)
Descriptor: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), Hepatocyte nuclear factor 3-beta, ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZF
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BU of 7yzf by Molmil
Crystal structure of the human FoxA2 bound to the TGTTTATT site (forkhead motif ATAAACA)
Descriptor: DNA (5'-D(P*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), Hepatocyte nuclear factor 3-beta, ...
Authors:Pluta, R, Macias, M.J.
Deposit date:2022-02-19
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
4G37
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BU of 4g37 by Molmil
Structure of cross-linked firefly luciferase in second catalytic conformation
Descriptor: 4,4'-(ethylenediimino)bis[4-oxobutyrate], 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, CHLORIDE ION, ...
Authors:Sundlov, J.A, Branchini, B.R, Gulick, A.M.
Deposit date:2012-07-13
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.
Biochemistry, 51, 2012
8QH3
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BU of 8qh3 by Molmil
5'vRNA-bound Hantaan virus polymerase in monomeric active state
Descriptor: MAGNESIUM ION, RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
Authors:Durieux Trouilleton, Q, Arragain, B, Malet, H.
Deposit date:2023-09-06
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Nat Commun, 15, 2024
7N2M
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BU of 7n2m by Molmil
Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2021-05-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional insight into mismatch extension by human DNA polymerase alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
8IUO
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BU of 8iuo by Molmil
respiratory syncytial virus nucleocapsid-like assembly
Descriptor: Nucleoprotein, RNA (35-MER)
Authors:Wang, Y, Luo, Y, Ling, X, Luo, B, Jia, G, Dong, H, Su, Z.
Deposit date:2023-03-24
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus.
Signal Transduct Target Ther, 8, 2023
7SGS
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BU of 7sgs by Molmil
Cryo-EM structure of full-length MAP7 bound to the microtubule
Descriptor: Ensconsin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Ferro, L.S, Fang, Q, Eshun-Wilson, L, Fernandes, J, Jack, A, Farrell, D.P, Golcuk, M, Huijben, T, Costa, K, Gur, M, DiMaio, F, Nogales, E, Yildiz, A.
Deposit date:2021-10-07
Release date:2022-05-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.
Science, 375, 2022
7BW4
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BU of 7bw4 by Molmil
Structure of the RNA-dependent RNA polymerase from SARS-CoV-2
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ...
Authors:Peng, Q, Peng, R, Shi, Y.
Deposit date:2020-04-13
Release date:2020-05-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2.
Cell Rep, 31, 2020
3WXM
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BU of 3wxm by Molmil
Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kobayashi, K, Ishitani, R, Nureki, O.
Deposit date:2014-08-04
Release date:2014-09-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex
Proc.Natl.Acad.Sci.USA, 107, 2010
8OP2
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BU of 8op2 by Molmil
Stacks of nucleocapsid rings of the N1-370 mutant of the human Respiratory Syncytial Virus
Descriptor: Nucleoprotein, RNA (70-mer)
Authors:Gonnin, L, Desfosses, A, Gutsche, I.
Deposit date:2023-04-06
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural landscape of the respiratory syncytial virus nucleocapsids.
Nat Commun, 14, 2023
8OOU
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BU of 8oou by Molmil
Double-ring nucleocapsid of the Respiratory Syncytial Virus
Descriptor: Nucleoprotein, RNA (70-mer)
Authors:Gonnin, L, Desfosses, A, Gutsche, I.
Deposit date:2023-04-06
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural landscape of the respiratory syncytial virus nucleocapsids.
Nat Commun, 14, 2023
7BLV
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BU of 7blv by Molmil
Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, NS3 helicase domain
Authors:Anindita, P.D, Grinkevich, P, Franta, Z.
Deposit date:2021-01-19
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase.
J.Biol.Chem., 298, 2022
7WWU
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BU of 7wwu by Molmil
ICP1 Csy complex
Descriptor: Csy1, Csy2, Csy3, ...
Authors:Zhang, M, Peng, R.
Deposit date:2022-02-14
Release date:2023-04-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
7BM0
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BU of 7bm0 by Molmil
Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with AMPPNP
Descriptor: MANGANESE (II) ION, NS3 helicase domain, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Anindita, P.D, Grinkevich, P, Franta, Z.
Deposit date:2021-01-19
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase.
J.Biol.Chem., 298, 2022
1ZBU
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BU of 1zbu by Molmil
crystal structure of full-length 3'-exonuclease
Descriptor: 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION
Authors:Cheng, Y, Patel, D.J.
Deposit date:2005-04-08
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
4QUU
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BU of 4quu by Molmil
Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)5
Descriptor: 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, Histone H4, ...
Authors:Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2014-07-12
Release date:2014-07-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.
J Mol Cell Biol, 8, 2016
7V2Y
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BU of 7v2y by Molmil
cryo-EM structure of yeast THO complex with Sub2
Descriptor: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ...
Authors:Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M.
Deposit date:2021-08-10
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex.
Sci Bull (Beijing), 66, 2021
5V5G
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BU of 5v5g by Molmil
OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4
Descriptor: 1,2-ETHANEDIOL, RNA-directed RNA polymerase L, SODIUM ION, ...
Authors:Khare, B, Mark, B.L.
Deposit date:2017-03-14
Release date:2017-05-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
PLoS Pathog., 13, 2017
6WYA
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BU of 6wya by Molmil
RTX (Reverse Transcription Xenopolymerase) in complex with a DNA duplex and dAMPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W.
Deposit date:2020-05-12
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:How a B family DNA polymerase has been evolved to copy RNA.
Proc.Natl.Acad.Sci.USA, 117, 2020

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数据于2024-07-17公开中

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