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6ONJ
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BU of 6onj by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone
Descriptor: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-04-22
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
6ONI
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BU of 6oni by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with N-CoR peptide and inverse agonist T0070907
Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, NCOR isoform c, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-04-22
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
5HLI
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BU of 5hli by Molmil
Structure of Disulfide formed AbfR
Descriptor: CHLORIDE ION, COPPER (II) ION, MarR family transcriptional regulator
Authors:Liu, G, Liu, X, Gan, J, Yang, C.-G.
Deposit date:2016-01-15
Release date:2017-01-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR.
J. Am. Chem. Soc., 139, 2017
5HLG
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BU of 5hlg by Molmil
Structure of reduced AbfR bound to DNA
Descriptor: DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator
Authors:Liu, G, Liu, X, Gan, J, Yang, C.G.
Deposit date:2016-01-15
Release date:2017-01-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR.
J. Am. Chem. Soc., 139, 2017
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
4LZL
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BU of 4lzl by Molmil
Structure of the inactive form of the regulatory domain from the repressor of iron transport regulator (RitR)
Descriptor: GLYCEROL, Response regulator
Authors:Silvaggi, N.R, Han, L, Ulijasz, A.T.
Deposit date:2013-07-31
Release date:2014-09-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Defining the Aspartate-Less Receiver (ALR) Domains: Structure and Activation of RitR from Streptococcus pneumoniae
To be Published
4JG3
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BU of 4jg3 by Molmil
Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa
Descriptor: CHLORIDE ION, Catabolite repression control protein
Authors:Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K.
Deposit date:2013-02-28
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
3C2I
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BU of 3c2i by Molmil
The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF
Descriptor: DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2
Authors:Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D.
Deposit date:2008-01-25
Release date:2008-05-13
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
6TBT
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BU of 6tbt by Molmil
Crystal structure of the BCL6 BTB domain in complex with an Apt48 peptide
Descriptor: Apt48 peptide, B-cell lymphoma 6 protein, CHLORIDE ION, ...
Authors:Zacharchenko, T, Wright, S.C.
Deposit date:2019-11-04
Release date:2021-10-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
6TCJ
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BU of 6tcj by Molmil
Crystal structure of the BCL6 BTB domain in complex with a hybrid BTB-binding (HBP) peptide
Descriptor: B-cell lymphoma 6 protein, Hybrid BTB-binding (HBP) peptide, SODIUM ION
Authors:Zacharchenko, T, Wright, S.C.
Deposit date:2019-11-06
Release date:2021-10-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
3ZMU
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BU of 3zmu by Molmil
LSD1-CoREST in complex with PKSFLV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PKSFLV PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-12
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZN0
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BU of 3zn0 by Molmil
LSD1-CoREST in complex with PRSFAA peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-13
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZMT
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BU of 3zmt by Molmil
LSD1-CoREST in complex with PRSFLV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-12
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZMV
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BU of 3zmv by Molmil
LSD1-CoREST in complex with PLSFLV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PKSFLV PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-12
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTH
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BU of 3hth by Molmil
Crystal structure of multidrug binding protein EbrR complexed with proflavin
Descriptor: EbrA repressor, NICKEL (II) ION, PROFLAVIN
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
3ZN1
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BU of 3zn1 by Molmil
LSD1-CoREST in complex with PRLYLV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-13
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTJ
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BU of 3htj by Molmil
Crystal structure of multidrug binding protein EbrR complexed with ethidium
Descriptor: ETHIDIUM, EbrA repressor, NICKEL (II) ION
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
3ZMZ
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BU of 3zmz by Molmil
LSD1-CoREST in complex with PRSFAV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-13
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTA
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BU of 3hta by Molmil
Crystal structure of multidrug binding protein EbrR complexed with imidazole
Descriptor: EbrA repressor, IMIDAZOLE
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
5U4J
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BU of 5u4j by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ...
Authors:Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
3PXP
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BU of 3pxp by Molmil
Crystal structure of a PAS and DNA binding domain containing protein (Caur_2278) from CHLOROFLEXUS AURANTIACUS J-10-FL at 2.30 A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Helix-turn-helix domain protein, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-12-10
Release date:2011-01-19
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes.
Plos One, 7, 2012
5U8K
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BU of 5u8k by Molmil
RitR mutant - C128S
Descriptor: Response regulator
Authors:Silvaggi, N.R, Han, L.
Deposit date:2016-12-14
Release date:2017-12-20
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
6J9B
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BU of 6j9b by Molmil
Arabidopsis FUS3-DNA complex
Descriptor: B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3')
Authors:Hu, H, Du, J.
Deposit date:2019-01-22
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
6JQ1
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BU of 6jq1 by Molmil
Crystal Structure of DdrO from Deinococcus geothermalis
Descriptor: LITHIUM ION, Transcriptional regulator, XRE family
Authors:Lu, H, Hua, Y, Zhao, Y.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO.
Nucleic Acids Res., 47, 2019
5EY0
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BU of 5ey0 by Molmil
Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
Descriptor: GTP-sensing transcriptional pleiotropic repressor CodY, GUANOSINE-5'-TRIPHOSPHATE, ISOLEUCINE
Authors:Han, A, Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016

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数据于2024-07-24公开中

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