2HK2
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2HKV
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2HLQ
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2HLJ
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2GK1
| X-ray crystal structure of NGT-bound HexA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Beta-hexosaminidase subunit alpha, ... | Authors: | Lemieux, M.J, Mark, B.L, Cherney, M.M, Withers, S.G, Mahuran, D.J, James, M.N. | Deposit date: | 2006-03-31 | Release date: | 2006-05-30 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystallographic Structure of Human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of G(M2) Ganglioside Hydrolysis. J.Mol.Biol., 359, 2006
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2GM8
| TenA Homolog/Thi-4 Thiaminase complexed with product 4-amino-5-hydroxymethyl-2-methylpyrimidine | Descriptor: | 1,2-ETHANEDIOL, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, tenA homolog/Thi-4 Thiaminase | Authors: | Sawaya, M.R, Chan, S, Han, G.W, Perry, L.J, Pashkov, I. | Deposit date: | 2006-04-06 | Release date: | 2006-04-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum To be Published
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2GQ3
| mycobacterium tuberculosis malate synthase in complex with magnesium, malate, and coenzyme A | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COENZYME A, D-MALATE, ... | Authors: | Anstrom, D.M, Remington, S.J. | Deposit date: | 2006-04-19 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The product complex of M. tuberculosis malate synthase revisited. Protein Sci., 15, 2006
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2GU5
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2GQG
| X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain | Descriptor: | GLYCEROL, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase ABL1 | Authors: | Klei, H.E. | Deposit date: | 2006-04-20 | Release date: | 2006-11-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants CANCER RES., 66, 2006
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2GSZ
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2H39
| Crystal Structure of an ADP-Glucose Phosphorylase from Arabidopsis thaliana with bound ADP-Glucose | Descriptor: | ADENOSINE-5'-DIPHOSPHATE-GLUCOSE, CHLORIDE ION, Probable galactose-1-phosphate uridyl transferase, ... | Authors: | McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-05-22 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal Structure of an ADP-Glucose Phosphorylase from Arabidopsis thaliana with bound ADP-Glucose To be Published
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2H56
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2H5K
| Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2 | Descriptor: | CACODYLATE ION, Growth factor receptor-bound protein 2, Shc-Derived Ligand | Authors: | Benfield, A.P, Whiddon, B.B, Martin, S.F. | Deposit date: | 2006-05-26 | Release date: | 2006-08-15 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
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2H0E
| Crystal Structure of PucM in the absence of substrate | Descriptor: | GLYCEROL, Transthyretin-like protein pucM | Authors: | Rhee, S. | Deposit date: | 2006-05-14 | Release date: | 2006-06-27 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GOX
| Crystal structure of Efb-C / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Hammel, M, Geisbrecht, B.V. | Deposit date: | 2006-04-14 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A structural basis for complement inhibition by Staphylococcus aureus. Nat.Immunol., 8, 2007
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2H2C
| Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTWV) | Descriptor: | Tight junction protein ZO-1 | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | Deposit date: | 2006-05-18 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
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2H73
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2HAH
| The structure of FIV 12S protease in complex with TL-3 | Descriptor: | Protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Heaslet, H, Lin, Y.C, Elder, J.H, Stout, C.D. | Deposit date: | 2006-06-12 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3. Retrovirology, 4, 2007
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2HQJ
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2HHL
| Crystal structure of the human small CTD phosphatase 3 isoform 1 | Descriptor: | 12-TUNGSTOPHOSPHATE, CTD small phosphatase-like protein | Authors: | Malashkevich, V.N, Toro, R, Ramagopal, U, Sauder, J.M, Schwinn, K.D, Thompson, D.A, Rutter, M.E, Dickey, M, Groshong, C, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Powell, A, Boice, A, Gheyi, T, Ozyurt, S, Atwell, S, Wasserman, S.R, Emtage, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-06-28 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
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2HHZ
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2HIV
| ATP-dependent DNA ligase from S. solfataricus | Descriptor: | Thermostable DNA ligase | Authors: | Pascal, J.M, Ellenberger, T. | Deposit date: | 2006-06-29 | Release date: | 2006-11-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
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2HO4
| Crystal Structure of Protein from Mouse Mm.236127 | Descriptor: | Haloacid dehalogenase-like hydrolase domain containing 2, MAGNESIUM ION, PHOSPHATE ION | Authors: | McCoy, J.G, Wesenberg, G.E, Bitto, E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-07-13 | Release date: | 2006-08-15 | Last modified: | 2018-03-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Protein from Mouse Mm.236127 To be published
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2HLZ
| Crystal Structure of human ketohexokinase | Descriptor: | Ketohexokinase, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-07-10 | Release date: | 2006-08-08 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of human ketohexokinase (CASP Target) To be Published
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2HOE
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