3DJG
 
 | | Catalytic cycle of human glutathione reductase near 1 A resolution | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Berkholz, D.S, Faber, H.R, Savvides, S.N, Karplus, P.A. | | Deposit date: | 2008-06-23 | | Release date: | 2008-08-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Catalytic cycle of human glutathione reductase near 1 A resolution.
J.Mol.Biol., 382, 2008
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6KEG
 | | BRD4 Bromodomain1 with an inhibitor | | Descriptor: | 6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(ethylsulfonylmethyl)pyridin-3-yl]-8-methyl-4H-pyrrolo[1,2-a]pyrazin-1-one, Bromodomain-containing protein 4 | | Authors: | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | | Deposit date: | 2019-07-04 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.232 Å) | | Cite: | BRD4 Bromodomain1 with an inhibitor
To Be Published
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6KEM
 | | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form 2 | | Descriptor: | Glutathione S-transferase E14 | | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | | Deposit date: | 2019-07-04 | | Release date: | 2019-10-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.
J.Biol.Chem., 295, 2020
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6KJT
 | | Functional and structural insights into the unusual oxyanion hole-like geometry in macrolactin acyltransferase selective for dicarboxylic acyl donors | | Descriptor: | Putative beta-lactamase, SUCCINIC ACID | | Authors: | Xiao, F, Dong, S, Feng, Y, Li, W. | | Deposit date: | 2019-07-23 | | Release date: | 2020-07-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.113 Å) | | Cite: | Structural Basis of Specificity for Carboxyl-Terminated Acyl Donors in a Bacterial Acyltransferase.
J.Am.Chem.Soc., 142, 2020
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6KKH
 | | Crystal structure of the oxalate bound malyl-CoA lyase from Roseiflexus castenholzii | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HpcH/HpaI aldolase, MAGNESIUM ION, ... | | Authors: | Tang, W.R, Wang, Z.G, Zhang, C.Y, Wang, C. | | Deposit date: | 2019-07-25 | | Release date: | 2019-09-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | The C-terminal domain conformational switch revealed by the crystal structure of malyl-CoA lyase from Roseiflexus castenholzii.
Biochem.Biophys.Res.Commun., 518, 2019
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6KEZ
 | | Crystal structure of GAPDH/CP12/PRK complex from Arabidopsis thaliana | | Descriptor: | Calvin cycle protein CP12-2, Glyceraldehyde-3-phosphate dehydrogenase GAPA1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Yu, A, Xie, Y, Li, M. | | Deposit date: | 2019-07-05 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle.
Plant Cell, 32, 2020
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6KGF
 | | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 8.2 | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGU
 | | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with aztreonam | | Descriptor: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, COBALT (II) ION, Penicillin-binding protein PbpB | | Authors: | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | | Deposit date: | 2019-07-12 | | Release date: | 2020-03-11 | | Method: | X-RAY DIFFRACTION (2.106 Å) | | Cite: | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation.
Mol.Pharmacol., 97, 2020
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3DL8
 | | Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | | Descriptor: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | | Authors: | Nam, Y, Zimmer, J, Rapoport, T.A. | | Deposit date: | 2008-06-26 | | Release date: | 2008-12-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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6KGX
 | | Structure of the phycobilisome from the red alga Porphyridium purpureum | | Descriptor: | Allophycocyanin alpha subunit, Allophycocyanin beta 18 subunit, Allophycocyanin beta subunit, ... | | Authors: | Sui, S.F, Ma, J.F, You, X, Sun, S. | | Deposit date: | 2019-07-12 | | Release date: | 2019-12-11 | | Last modified: | 2020-03-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis of energy transfer in Porphyridium purpureum phycobilisome.
Nature, 579, 2020
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6KLS
 | | Hyperthermophilic respiratory Complex III | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-[(2~{E},6~{E},10~{Z},14~{Z},18~{Z},23~{R})-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18-pentaenyl]naphthalene-1,4-dione, Cytochrome c, ... | | Authors: | Fei, S, Hartmut, M, Yun, Z, Guohong, P, Guoliang, Z, Hui, Z, Shuangbo, Z, Xiaoyun, P, Yan, Z. | | Deposit date: | 2019-07-30 | | Release date: | 2020-05-13 | | Last modified: | 2021-04-07 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A 3.3 angstrom -Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of Its Thermal Stability.
Angew.Chem.Int.Ed.Engl., 59, 2020
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4KHP
 | | Structure of the Thermus thermophilus 30S ribosomal subunit in complex with de-6-MSA-pactamycin | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal protein S10, 30S Ribosomal protein S11, ... | | Authors: | Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V. | | Deposit date: | 2013-05-01 | | Release date: | 2013-06-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit.
J.Mol.Biol., 425, 2013
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6KM6
 | | Human Carbonic Anhydrase II native 15 atm CO2 | | Descriptor: | CARBON DIOXIDE, Carbonic anhydrase 2, GLYCEROL, ... | | Authors: | Kim, C.U, Kim, J.K. | | Deposit date: | 2019-07-30 | | Release date: | 2020-08-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
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6KNC
 | | PolD-PCNA-DNA (form B) | | Descriptor: | DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ... | | Authors: | Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y. | | Deposit date: | 2019-08-05 | | Release date: | 2020-08-05 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
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6K7W
 | | Solution Structure of the CS1 Domain of USP19 | | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 19 | | Authors: | Xue, W, Hu, H.Y. | | Deposit date: | 2019-06-10 | | Release date: | 2020-06-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
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6JT0
 | | Structure of human soluble guanylate cyclase in the unliganded state | | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | | Deposit date: | 2019-04-08 | | Release date: | 2019-08-28 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase.
Nature, 574, 2019
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6JTC
 | | Crystal structure of dipeptidyl peptidase 11 (DPP11) with SH-5 from Porphyromonas gingivalis (Space) | | Descriptor: | 2-(2-azanylethylamino)-5-nitro-benzoic acid, Asp/Glu-specific dipeptidyl-peptidase, GLYCEROL | | Authors: | Sakamoto, Y, Suzuki, Y, Iizuka, I, Roppongi, S, Kushibiki, C, Nakamura, A, Ogasawara, W, Tanaka, N. | | Deposit date: | 2019-04-10 | | Release date: | 2019-10-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sci Rep, 9, 2019
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6JXC
 | | Tel1 kinase butterfly symmetric dimer | | Descriptor: | Serine/threonine-protein kinase TEL1 | | Authors: | Xin, J. | | Deposit date: | 2019-04-23 | | Release date: | 2019-07-03 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of allosteric regulation of Tel1/ATM kinase.
Cell Res., 29, 2019
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6JTU
 | | Crystal structure of MHETase from Ideonella sakaiensis | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Sagong, H.-Y, Seo, H, Kim, K.-J. | | Deposit date: | 2019-04-12 | | Release date: | 2020-04-15 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Decomposition of PET film by MHETase using Exo-PETase function
Acs Catalysis, 10, 2020
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6JUE
 | | The complex of PDZ and PBM | | Descriptor: | Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU | | Authors: | Liu, Z. | | Deposit date: | 2019-04-13 | | Release date: | 2020-04-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.549 Å) | | Cite: | Par complex cluster formation mediated by phase separation.
Nat Commun, 11, 2020
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6JUG
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6JUN
 | | MsDpo4-DNA complex 3 | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | | Authors: | Nair, D.T, Johnson, M.K. | | Deposit date: | 2019-04-15 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation.
Nucleic Acids Res., 47, 2019
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6JY6
 | | Structure of dark-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 95K. | | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | | Authors: | Yun, J.H, Ohki, M, Park, S.Y, Lee, W. | | Deposit date: | 2019-04-26 | | Release date: | 2020-03-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
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6JYC
 | | Structure of dark-state marine bacterial chloride importer, NM-R3, with CW laser (ND-30%) at 95K. | | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | | Authors: | Yun, J.H, Ohki, M, Park, S.Y, Lee, W. | | Deposit date: | 2019-04-26 | | Release date: | 2020-03-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family.
Sci Adv, 6, 2020
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6JYU
 | | Crystal structure of Human G6PD Canton | | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Au, S.W.N. | | Deposit date: | 2019-04-28 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Crystal structure of Human G6PD Canton
To Be Published
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