PDB: 46984 resultsInfo pagesStatus searchChemie searchBIRD

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6EM3	State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... Authors: Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. Deposit date: 2017-10-01 Release date: 2017-12-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
6OVR	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.843 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
8FKP	Human nucleolar pre-60S ribosomal subunit (State A1) Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L13, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKY	Human nucleolar pre-60S ribosomal subunit (State F) Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKV	Human nucleolar pre-60S ribosomal subunit (State D1) Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.47 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKX	Human nucleolar pre-60S ribosomal subunit (State E) Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL0	Human nucleolar pre-60S ribosomal subunit (State H) Descriptor: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8G1S	Cryo-EM structure of 3DVA component 1 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase minus preQ1 ligand Descriptor: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. Deposit date: 2023-02-02 Release date: 2023-06-21 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
8FZ6	The human PI31 complexed with bovine 20S proteasome Descriptor: Proteasome inhibitor PI31 subunit, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... Authors: Hsu, H.-C, Li, H. Deposit date: 2023-01-27 Release date: 2023-07-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: Eta igh-resolution structure of mammalian PI31-20S proteasome complex reveals mechanism of proteasome inhibition. J.Biol.Chem., 299, 2023
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OW3	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-09 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.766 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY6	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.096 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
8G4S	40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs. Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... Authors: Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. Deposit date: 2023-02-10 Release date: 2024-01-31 Last modified: 2024-04-17 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
6OY5	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6ENJ	Polyproline-stalled ribosome in the presence of A+P site tRNA and elongation-factor P (EF-P) Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Huter, P, Wilson, D.N. Deposit date: 2017-10-05 Release date: 2017-11-22 Last modified: 2019-10-30 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Mol. Cell, 68, 2017
2ZJR	Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. Deposit date: 2008-03-08 Release date: 2008-06-17 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
8G7S	Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the cognate AUA codon (Structure IV) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
8G7Q	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
6P67	Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ... Authors: Walsh, S.T.R, Kashi, L, Kohnhorst, C.L. Deposit date: 2019-06-03 Release date: 2019-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia, 34, 2020
6ELZ	State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... Authors: Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. Deposit date: 2017-09-30 Release date: 2017-12-27 Last modified: 2023-02-15 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
8G7R	Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
6PAM	Structure of a bacterial Atm1-family ABC transporter with MgADP bound Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION Authors: Fan, C, Kaiser, J.T, Rees, D.C. Deposit date: 2019-06-11 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.7 Å) Cite: A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
8G7P	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
6EFJ	Crystal structure of NDM-1 with compound 9 Descriptor: (2R)-2-phenyl-2-(phenylamino)-N-(1H-tetrazol-5-yl)acetamide, Metallo-beta-lactamase type 2, ZINC ION Authors: Akhtar, A, Chen, Y. Deposit date: 2018-08-16 Release date: 2019-04-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
6EML	Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae Descriptor: 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... Authors: Heuer, A, Thomson, E, Schmidt, C, Berninghausen, O, Becker, T, Hurt, E, Beckmann, R. Deposit date: 2017-10-02 Release date: 2017-11-29 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structure of a late pre-40S ribosomal subunit fromSaccharomyces cerevisiae. Elife, 6, 2017

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