8PMV
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1POG
| SOLUTION STRUCTURE OF THE OCT-1 POU-HOMEO DOMAIN DETERMINED BY NMR AND RESTRAINED MOLECULAR DYNAMICS | Descriptor: | OCT-1 POU HOMEODOMAIN DNA-BINDING PROTEIN | Authors: | Cox, M, Van Tilborg, P.J.A, De Laat, W, Boelens, R, Van Leeuwen, H.C, Van Der Vliet, P.C, Kaptein, R. | Deposit date: | 1994-10-12 | Release date: | 1995-07-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics. J.Biomol.NMR, 6, 1995
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1P7J
| Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1QRY
| Homeobox protein VND (ventral nervous system defective protein) | Descriptor: | PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) | Authors: | Xiang, B. | Deposit date: | 1999-06-16 | Release date: | 1999-07-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation. Biochemistry, 42, 2003
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1OCP
| SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN | Descriptor: | OCT-3 | Authors: | Morita, E.H, Hayashi, F, Shirakawa, M, Kyogoku, Y. | Deposit date: | 1995-02-21 | Release date: | 1995-09-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the Oct-3 POU-Homeodomain in Solution, as Determined by Triple Resonance Heteronuclear Multidimensional NMR Spectroscopy Protein Sci., 4, 1995
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1P7I
| CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1PUF
| Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA | Descriptor: | 5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*CP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*AP*GP*AP*G)-3', Homeobox protein Hox-A9, ... | Authors: | Laronde-Leblanc, N.A, Wolberger, C. | Deposit date: | 2003-06-24 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | STRUCTURE OF HOXA9 AND PBX1 BOUND TO DNA: HOX HEXAPEPTIDE AND DNA RECOGNITION ANTERIOR TO POSTERIOR Genes Dev., 17, 2003
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1NK3
| VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND | Authors: | Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. | Deposit date: | 1998-05-06 | Release date: | 1998-12-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
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1NK2
| VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, 20 STRUCTURES | Descriptor: | DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND | Authors: | Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. | Deposit date: | 1998-05-06 | Release date: | 1999-02-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
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1SAN
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2KT0
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2HOT
| Phage selected homeodomain bound to modified DNA | Descriptor: | 3-PROP-2-YN-1-YL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... | Authors: | Feldman, M.E, Simon, M.D, Shokat, K.M. | Deposit date: | 2006-07-16 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure and properties of a re-engineered homeodomain protein-DNA interface. Acs Chem.Biol., 1, 2006
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2HI3
| Solution structure of the homeodomain-only protein HOP | Descriptor: | Homeodomain-only protein | Authors: | Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W. | Deposit date: | 2006-06-28 | Release date: | 2007-01-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Analysis of the structure and function of the transcriptional coregulator HOP Biochemistry, 45, 2006
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2L7M
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2LKX
| NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site | Descriptor: | DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), Pituitary homeobox 3 | Authors: | Baird-Titus, J.M, Doerdelmann, T, Chaney, B.A, Clark-Baldwin, K, Dave, V, Ma, J. | Deposit date: | 2011-10-21 | Release date: | 2012-05-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome Biochemistry, 44, 2005
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2HOA
| STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA | Descriptor: | ANTENNAPEDIA PROTEIN | Authors: | Guntert, P, Qian, Y.-Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | Deposit date: | 1992-04-04 | Release date: | 1993-10-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA. J.Mol.Biol., 217, 1991
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2HOS
| Phage-Selected Homeodomain Bound to Unmodified DNA | Descriptor: | 3-METHYL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... | Authors: | Shokat, K.M, Feldman, M.E, Simon, M.D. | Deposit date: | 2006-07-16 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and properties of a re-engineered homeodomain protein-DNA interface. Acs Chem.Biol., 1, 2006
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2K40
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2JWT
| Solution structure of Engrailed homeodomain WT | Descriptor: | Segmentation polarity homeobox protein engrailed | Authors: | Religa, T.L. | Deposit date: | 2007-10-24 | Release date: | 2008-04-01 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Comparison of multiple crystal structures with NMR data for engrailed homeodomain J.Biomol.Nmr, 40, 2008
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2L7F
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2LP0
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2L7Z
| NMR Structure of A13 homedomain | Descriptor: | Homeobox protein Hox-A13 | Authors: | Ames, J. | Deposit date: | 2010-12-27 | Release date: | 2011-11-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. Plos One, 6, 2011
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2LD5
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2ME6
| NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG | Descriptor: | DNA (5'-D(*CP*GP*AP*CP*TP*AP*AP*TP*TP*AP*GP*TP*CP*G)-3'), Homeobox protein GBX-1 | Authors: | Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) | Deposit date: | 2013-09-23 | Release date: | 2013-10-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG To be Published
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2MGQ
| Structure of CEH37 Homeodomain | Descriptor: | Homeobox protein ceh-37 | Authors: | Moon, S, Lee, W. | Deposit date: | 2013-11-04 | Release date: | 2014-11-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of CEH37 Homeodomain To be Published
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