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1PBF
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BU of 1pbf by Molmil
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor: 2-HYDROXY-4-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
Authors:Schreuder, H.A, Van Der Bolt, F.J.T, Van Berkel, W.J.H.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBD
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BU of 1pbd by Molmil
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor: 4-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
Authors:Schreuder, H.A, Mattevi, A, Hol, W.G.J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBB
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BU of 1pbb by Molmil
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor: 2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
Authors:Schreuder, H.A, Mattevi, A, Hol, W.G.J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
6CTB
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BU of 6ctb by Molmil
Apo-Calmodulin Bound to Calcium Voltage Gated Channel 1.2 IQ-Motif
Descriptor: Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Turner, M.L, Anderson, D.E, Ames, J.B.
Deposit date:2018-03-22
Release date:2019-09-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:apo-Calmodulin Bound to Calcium Voltage Gated Channel 1.2 IQ-Motif
To Be Published
3V7T
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BU of 3v7t by Molmil
Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
Descriptor: CARBONATE ION, TPSB2 protein, {(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone
Authors:Zhang, Y, Colonna, C, Michot, N.
Deposit date:2011-12-22
Release date:2012-03-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
Bioorg.Med.Chem.Lett., 22, 2012
7ZRL
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BU of 7zrl by Molmil
Cryo-EM map of the unphosphorylated KdpFABC complex in the E2-P conformation, under turnover conditions
Descriptor: POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, Potassium-transporting ATPase KdpC subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
2M0Q
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BU of 2m0q by Molmil
Solution NMR analysis of intact KCNE2 in detergent micelles demonstrate a straight transmembrane helix
Descriptor: Potassium voltage-gated channel subfamily E member 2
Authors:Lai, C, Li, P, Chen, L, Zhang, L, Wu, F, Tian, C.
Deposit date:2012-11-01
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2.
Sci Rep, 4, 2014
2CK5
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BU of 2ck5 by Molmil
Solution structure of Delta 1-7 aOSK1
Descriptor: POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.7
Authors:Alphonse, S, Mouhat, S, Sabatier, J.M, Darbon, H, Bernard, C.
Deposit date:2006-04-10
Release date:2007-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Two Analogues of the Osk1 Toxin
To be Published
2CK4
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BU of 2ck4 by Molmil
Solution Structure of aOSK1
Descriptor: POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.7
Authors:Alphonse, S, Mouhat, S, Sabatier, J.M, Darbon, H, Bernard, C.
Deposit date:2006-04-10
Release date:2007-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Two Analogues of the Osk1 Toxin
To be Published
6V4J
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BU of 6v4j by Molmil
Structure of TrkH-TrkA in complex with ATP
Descriptor: Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH
Authors:Zhou, M, Zhang, H.
Deposit date:2019-11-27
Release date:2020-02-12
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential.
Nat Commun, 11, 2020
6ATM
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BU of 6atm by Molmil
Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
Descriptor: Potassium channel toxin alpha-KTx 3.10
Authors:Gewe, M.M, Rupert, P, Strong, R.K.
Deposit date:2017-08-29
Release date:2018-08-22
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
To Be Published
6AY8
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BU of 6ay8 by Molmil
Cartilage homing cysteine-dense-peptides
Descriptor: Potassium channel toxin alpha-KTx 15.8, SULFATE ION
Authors:Gewe, M.M, Strong, R.K, Watson, A.
Deposit date:2017-09-07
Release date:2018-08-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Cartilage homing cysteine-dense-peptides
To Be Published
4WWS
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BU of 4wws by Molmil
Structure of Chlorite dismutase-like Protein from Listeria monocytogenes
Descriptor: POTASSIUM ION, Putative heme-dependent peroxidase lmo2113
Authors:Hagmueller, A, Mlynek, G, Djinovic-Carugo, K.
Deposit date:2014-11-12
Release date:2015-02-04
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes.
Arch.Biochem.Biophys., 574, 2015
2RTZ
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BU of 2rtz by Molmil
Solution structure of MarkTX-7
Descriptor: Potassium channel blocker MarkTX-7
Authors:Umetsu, Y, Ohki, S.
Deposit date:2013-10-17
Release date:2014-10-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of MarkTX-7
To be Published
1WJX
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BU of 1wjx by Molmil
Crystal sturucture of TT0801 from Thermus thermophilus
Descriptor: POTASSIUM ION, SsrA-binding protein
Authors:Bessho, Y, Shibata, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-29
Release date:2004-11-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2MLD
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BU of 2mld by Molmil
Solution structure of BmKTX-D19K/K6D
Descriptor: Potassium channel toxin alpha-KTx 3.6
Authors:Hong, J, Lin, D, Chen, Z, Wu, Y.
Deposit date:2014-02-24
Release date:2015-02-25
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE of BMKTX-D19K
To be Published
2MLA
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BU of 2mla by Molmil
Solution structure of BmKTX-D19K
Descriptor: Potassium channel toxin alpha-KTx 3.6
Authors:Hong, J, Lin, D, Chen, Z, Wu, Y.
Deposit date:2014-02-21
Release date:2015-02-25
Method:SOLUTION NMR
Cite:Solution structure of BmKTX-D19K
To be Published
6GSH
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BU of 6gsh by Molmil
Feline Calicivirus Strain F9
Descriptor: POTASSIUM ION, VP1
Authors:Conley, M.J, Bhella, D.
Deposit date:2018-06-14
Release date:2019-01-16
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Calicivirus VP2 forms a portal-like assembly following receptor engagement.
Nature, 565, 2019
3EXG
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BU of 3exg by Molmil
Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex
Descriptor: POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, ...
Authors:Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T.
Deposit date:2008-10-16
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Structure, 16, 2008
6OCP
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BU of 6ocp by Molmil
Crystal structure of a human GABAB receptor peptide bound to KCTD16 T1
Descriptor: BTB/POZ domain-containing protein KCTD16, Gamma-aminobutyric acid type B receptor subunit 2
Authors:Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R.
Deposit date:2019-03-25
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
2E6W
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BU of 2e6w by Molmil
Solution structure and calcium binding properties of EF-hands 3 and 4 of calsenilin
Descriptor: CALCIUM ION, Calsenilin
Authors:Yu, L, Sun, C, Mendoza, R, Hebert, E, Pereda-Lopez, A, Hajduk, P.J, Olejniczak, E.T.
Deposit date:2007-01-05
Release date:2007-11-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin.
Protein Sci., 16, 2007
5XXI
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BU of 5xxi by Molmil
Crystal structure of CYP2C9 in complex with multiple losartan molecules
Descriptor: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Maekawa, K, Adachi, M, Shah, M.B.
Deposit date:2017-07-04
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
8QA2
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BU of 8qa2 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA3
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BU of 8qa3 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation
Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Brotherton, D.H, Cameron, A.D.
Deposit date:2023-08-22
Release date:2024-06-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
6V00
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BU of 6v00 by Molmil
structure of human KCNQ1-KCNE3-CaM complex
Descriptor: CALCIUM ION, Calmodulin-1, MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3, ...
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-16
Release date:2019-12-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020

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数据于2024-10-02公开中

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