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3M35
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BU of 3m35 by Molmil
Trypsin in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
Descriptor: 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Cationic trypsin
Authors:Alexander, R.S.
Deposit date:2010-03-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor
J.Med.Chem., 46, 2003
3DEE
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BU of 3dee by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE REGULATORY PROTEIN INVOLVED IN TRANSCRIPTION (NGO1945) FROM NEISSERIA GONORRHOEAE FA 1090 AT 2.25 A RESOLUTION
Descriptor: CHLORIDE ION, IMIDAZOLE, Putative regulatory protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-06-09
Release date:2008-08-05
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
Acta Crystallogr.,Sect.F, 66, 2010
3M8L
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BU of 3m8l by Molmil
Crystal Structure Analysis of the Feline Calicivirus Capsid Protein
Descriptor: Capsid protein
Authors:Zhou, Y, Prasad, B.V.V.
Deposit date:2010-03-18
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Conformational changes in the capsid of a calicivirus upon interaction with its functional receptor
J.Virol., 84, 2010
2ZG2
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BU of 2zg2 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5
Descriptor: Sialic acid-binding Ig-like lectin 5
Authors:Zhuravleva, M.A, Sun, P.D.
Deposit date:2008-01-17
Release date:2008-02-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
3J98
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BU of 3j98 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)
Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
Authors:Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
2ZSR
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BU of 2zsr by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 120 K: Laser on [450 min]
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
Deposit date:2008-09-17
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZT0
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BU of 2zt0 by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 100 K: Laser on [750 min]
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
Deposit date:2008-09-18
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZWB
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BU of 2zwb by Molmil
Neutron crystal structure of wild type human lysozyme in D2O
Descriptor: Lysozyme C
Authors:Chiba-Kamoshida, K, Matsui, T, Chatake, T, Ohhara, T, Ostermann, A, Tanaka, I, Yutani, K, Niimura, N.
Deposit date:2008-12-02
Release date:2009-12-08
Last modified:2023-11-01
Method:NEUTRON DIFFRACTION (1.8 Å)
Cite:Site-specific softening of peptide bonds by localized deuterium observed by neutron crystallography of human lysozyme
To be Published
3JC5
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BU of 3jc5 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
2ZSY
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BU of 2zsy by Molmil
Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [750 min]
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S.
Deposit date:2008-09-18
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZUT
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BU of 2zut by Molmil
Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, GLYCEROL, Lacto-N-biose phosphorylase, ...
Authors:Hidaka, M, Nishimoto, M, Kitaoka, M, Wakagi, T, Shoun, H, Fushinobu, S.
Deposit date:2008-10-28
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of galacto-N-biose/lacto-N-biose I phosphorylase: A large deformation of a tim barrel scaffold
J.Biol.Chem., 284, 2009
3JA8
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BU of 3ja8 by Molmil
Cryo-EM structure of the MCM2-7 double hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
Authors:Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
Deposit date:2015-05-09
Release date:2015-08-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
3JCJ
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BU of 3jcj by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
7XS0
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BU of 7xs0 by Molmil
Trimer structure of HtrA from Helicobacter pylori bound with a tripeptide
Descriptor: Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK
Authors:Cui, L, Liu, W.
Deposit date:2022-05-12
Release date:2023-05-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements.
Int.J.Biol.Macromol., 243, 2023
3C90
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BU of 3c90 by Molmil
The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II
Descriptor: Phosphoribosyl-ATP pyrophosphatase
Authors:Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2008-02-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
7XS2
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BU of 7xs2 by Molmil
Monomer structure of HtrA from Helicobacter pylori
Descriptor: Periplasmic serine endoprotease DegP-like
Authors:Cui, L, Liu, W.
Deposit date:2022-05-12
Release date:2023-05-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements.
Int.J.Biol.Macromol., 243, 2023
3BT1
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BU of 3bt1 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3J7Y
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BU of 3j7y by Molmil
Structure of the large ribosomal subunit from human mitochondria
Descriptor: 16S rRNA, ADENOSINE MONOPHOSPHATE, CRIF1, ...
Authors:Brown, A, Amunts, A, Bai, X.C, Sugimoto, Y, Edwards, P.C, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
7XYK
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BU of 7xyk by Molmil
Structure of WSSV thymidylate synthase in complex with dUMP and raltitrexed
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, SULFATE ION, TOMUDEX, ...
Authors:Ma, Q, Liu, C, Zang, K.
Deposit date:2022-06-01
Release date:2023-06-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.433 Å)
Cite:Structure of WSSV thymidylate synthase in complex with dUMP and raltitrexed
To Be Published
7XYJ
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BU of 7xyj by Molmil
Structure of WSSV thymidylate synthase in complex with dUMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PENTAETHYLENE GLYCOL, ...
Authors:Ma, Q, Liu, C, Zang, K.
Deposit date:2022-06-01
Release date:2023-06-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.275 Å)
Cite:Structure of WSSV thymidylate synthase in complex with dUMP
To Be Published
3BON
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BU of 3bon by Molmil
Structure of the C. botulinum neurotoxin serotype A with Zn2+ cofactor bound
Descriptor: Neurotoxin A, ZINC ION
Authors:Silvaggi, N.R, Allen, K.N.
Deposit date:2007-12-17
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex.
Biochemistry, 47, 2008
3BT2
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BU of 3bt2 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3CW1
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BU of 3cw1 by Molmil
Crystal Structure of Human Spliceosomal U1 snRNP
Descriptor: Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...
Authors:Pomeranz Krummel, D.A, Oubridge, C, Leung, A.K, Li, J, Nagai, K.
Deposit date:2008-04-21
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.493 Å)
Cite:Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
3J97
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BU of 3j97 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II)
Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
Authors:Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3JCN
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BU of 3jcn by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016

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数据于2024-08-28公开中

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