3NUG
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4OPF
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![BU of 4opf by Molmil](/molmil-images/mine/4opf) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 | Descriptor: | NRPS/PKS | Authors: | Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-02-05 | Release date: | 2014-02-19 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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3NPY
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![BU of 3npy by Molmil](/molmil-images/mine/3npy) | Crystal Structure of Tyrosinase from Bacillus megaterium soaked in CuSO4 | Descriptor: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.192 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
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1CNS
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3Q00
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![BU of 3q00 by Molmil](/molmil-images/mine/3q00) | Bovine trypsin variant X(tripleGlu217Ile227) in complex with small molecule inhibitor | Descriptor: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, CALCIUM ION, Cationic trypsin, ... | Authors: | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | Deposit date: | 2010-12-15 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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3PM3
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![BU of 3pm3 by Molmil](/molmil-images/mine/3pm3) | Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | Deposit date: | 2010-11-16 | Release date: | 2011-12-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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3PLB
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![BU of 3plb by Molmil](/molmil-images/mine/3plb) | Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | Deposit date: | 2010-11-15 | Release date: | 2011-12-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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4PF7
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![BU of 4pf7 by Molmil](/molmil-images/mine/4pf7) | Crystal structure of insulin degrading enzyme complexed with inhibitor | Descriptor: | (2S)-2-amino-N-{(1S)-1-cyclohexyl-2-[(4-methylphenyl)amino]-2-oxoethyl}-4-(methylselanyl)butanamide, Insulin-degrading enzyme, ZINC ION | Authors: | Wang, Y, Guo, S. | Deposit date: | 2014-04-28 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J.Biol.Chem., 290, 2015
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1O0O
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![BU of 1o0o by Molmil](/molmil-images/mine/1o0o) | Ribonuclease A in complex with adenosine-2',5'-diphosphate | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | Deposit date: | 2003-02-24 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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4QCA
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![BU of 4qca by Molmil](/molmil-images/mine/4qca) | Crystal structure of Vaccinia virus uracil-DNA glycosylase mutant R167AD4 | Descriptor: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Sartmatova, D, Nash, T, Schormann, N, Nuth, M, Ricciardi, R, Banerjee, S, Chattopadhyay, D. | Deposit date: | 2014-05-09 | Release date: | 2015-05-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr.,Sect.F, 69, 2013
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1R13
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![BU of 1r13 by Molmil](/molmil-images/mine/1r13) | Carbohydrate recognition and neck domains of surfactant protein A (SP-A) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Pulmonary surfactant-associated protein A, ... | Authors: | Head, J.F, Mealy, T.R, McCormack, F.X, Seaton, B.A. | Deposit date: | 2003-09-23 | Release date: | 2003-11-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A J.Biol.Chem., 278, 2003
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1R14
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![BU of 1r14 by Molmil](/molmil-images/mine/1r14) | Carbohydrate recognition and neck domains of surfactant protein A (Sp-A) containing samarium | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Pulmonary surfactant-associated protein A, SAMARIUM (III) ION | Authors: | Head, J.F, Mealy, T.R, McCormack, F.X, Seaton, B.A. | Deposit date: | 2003-09-23 | Release date: | 2003-11-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A J.Biol.Chem., 278, 2003
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4Q4I
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![BU of 4q4i by Molmil](/molmil-images/mine/4q4i) | Crystal structure of E.coli aminopeptidase N in complex with amastatin | Descriptor: | Amastatin, Aminopeptidase N, GLYCEROL, ... | Authors: | Reddi, R, Ganji, R.J, Addlagatta, A. | Deposit date: | 2014-04-14 | Release date: | 2015-04-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci., 24, 2015
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1QJ5
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![BU of 1qj5 by Molmil](/molmil-images/mine/1qj5) | Crystal structure of 7,8-diaminopelargonic acid synthase | Descriptor: | 7,8-DIAMINOPELARGONIC ACID SYNTHASE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE | Authors: | Kack, H, Sandmark, J, Gibson, K.J, Lindqvist, Y, Schneider, G. | Deposit date: | 1999-06-21 | Release date: | 2000-06-22 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Diaminopelargonic Acid Synthase; Evolutionary Relationships between Pyridoxal-5'-Phosphate Dependent Enzymes J.Mol.Biol., 291, 1999
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2IOG
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2IOK
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2J9I
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![BU of 2j9i by Molmil](/molmil-images/mine/2j9i) | Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens. | Descriptor: | GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1 | Authors: | Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G. | Deposit date: | 2006-11-09 | Release date: | 2006-12-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens. Structure, 14, 2006
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4NUJ
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3NTM
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![BU of 3ntm by Molmil](/molmil-images/mine/3ntm) | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of zinc, partial occupancy of CuB | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-07-05 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity J.Mol.Biol., 405, 2011
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5T04
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![BU of 5t04 by Molmil](/molmil-images/mine/5t04) | STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, ARG-ARG-PRO-TYR-ILE-LEU, DI(HYDROXYETHYL)ETHER, ... | Authors: | Krumm, B, Botos, I, Grisshammer, R. | Deposit date: | 2016-08-15 | Release date: | 2016-12-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure and dynamics of a constitutively active neurotensin receptor. Sci Rep, 6, 2016
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4Q0S
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![BU of 4q0s by Molmil](/molmil-images/mine/4q0s) | Crystal structure of Acinetobacter sp. DL28 L-ribose isomerase in complex with ribitol | Descriptor: | COBALT (II) ION, COBALT HEXAMMINE(III), D-ribitol, ... | Authors: | Yoshida, H, Yoshihara, A, Teraoka, M, Izumori, K, Kamitori, S. | Deposit date: | 2014-04-02 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate. Febs J., 281, 2014
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4QH4
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3A5U
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![BU of 3a5u by Molmil](/molmil-images/mine/3a5u) | Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex | Descriptor: | DNA (31-MER), Single-stranded DNA-binding protein | Authors: | Kaushal, P.S, Manjunath, G.P, Sekar, K, Muniyappa, K, Vijayan, M. | Deposit date: | 2009-08-12 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex. To be Published, 2009
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1EYS
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![BU of 1eys by Molmil](/molmil-images/mine/1eys) | CRYSTAL STRUCTURE OF PHOTOSYNTHETIC REACTION CENTER FROM A THERMOPHILIC BACTERIUM, THERMOCHROMATIUM TEPIDUM | Descriptor: | 2-O-octyl-beta-D-glucopyranose, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | Authors: | Nogi, T, Fathir, I, Kobayashi, M, Nozawa, T, Miki, K. | Deposit date: | 2000-05-08 | Release date: | 2000-12-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer. Proc.Natl.Acad.Sci.USA, 97, 2000
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4PX5
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![BU of 4px5 by Molmil](/molmil-images/mine/4px5) | Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate | Descriptor: | D-SORBITOL-6-PHOSPHATE, GLYCEROL, Glucokinase regulatory protein, ... | Authors: | Jordan, S.R, Chmait, S. | Deposit date: | 2014-03-21 | Release date: | 2015-05-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery and Structure Guided Optimization of Diarylmethanesulfonamide Disruptors of GK-GKRP Binding To be Published
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