4JI7
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![BU of 4ji7 by Molmil](/molmil-images/mine/4ji7) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | Authors: | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-03-05 | Release date: | 2013-11-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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2P6Z
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3MG8
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![BU of 3mg8 by Molmil](/molmil-images/mine/3mg8) | Structure of yeast 20S open-gate proteasome with Compound 16 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(2,2-dimethylpropyl)-N~2~-[1H-indol-3-yl(oxo)acetyl]-L-asparaginyl-N-(2-methylbenzyl)-3-pyridin-4-yl-L-alaninamide, ... | Authors: | Sintchak, M.D. | Deposit date: | 2010-04-05 | Release date: | 2011-05-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem.J., 430, 2010
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4JVY
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![BU of 4jvy by Molmil](/molmil-images/mine/4jvy) | Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA | Descriptor: | Female germline-specific tumor suppressor gld-1, RNA (5'-R(P*CP*UP*AP*AP*CP*AP*A)-3') | Authors: | Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J. | Deposit date: | 2013-03-26 | Release date: | 2013-05-08 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.853 Å) | Cite: | Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes Dev., 27, 2013
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3MMS
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![BU of 3mms by Molmil](/molmil-images/mine/3mms) | Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine | Descriptor: | 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase, 9H-purine-6,8-diamine, GLYCEROL | Authors: | Siu, K.K.W, Lee, J.E, Horvatin-Mrakovcic, C, Howell, P.L. | Deposit date: | 2010-04-20 | Release date: | 2010-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine TO BE PUBLISHED
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4NN3
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![BU of 4nn3 by Molmil](/molmil-images/mine/4nn3) | Crystal structure of a TRAP periplasmic solute binding protein from Desulfovibrio salexigens (Desal_2161), Target EFI-510109, with bound orotic acid | Descriptor: | CHLORIDE ION, OROTIC ACID, TRAP dicarboxylate transporter, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-11-16 | Release date: | 2013-12-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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2P8V
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![BU of 2p8v by Molmil](/molmil-images/mine/2p8v) | Crystal structure of human Homer3 EVH1 domain | Descriptor: | Homer protein homolog 3, SULFATE ION | Authors: | Bouyain, S, Tu, J, Huang, G.N, Worley, P.F, Leahy, D. | Deposit date: | 2007-03-23 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science, 319, 2008
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4WQ0
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2PE7
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![BU of 2pe7 by Molmil](/molmil-images/mine/2pe7) | Thaumatin from Thaumatococcus Danielli in complex with tris-dipicolinate Europium | Descriptor: | EUROPIUM ION, L(+)-TARTARIC ACID, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | Authors: | Pompidor, G, Vicat, J, Kahn, R. | Deposit date: | 2007-04-02 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction. Acta Crystallogr.,Sect.D, 66, 2010
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3GDH
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![BU of 3gdh by Molmil](/molmil-images/mine/3gdh) | Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form) | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, R-1,2-PROPANEDIOL, S-1,2-PROPANEDIOL, ... | Authors: | Monecke, T, Dickmanns, A, Ficner, R. | Deposit date: | 2009-02-24 | Release date: | 2009-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1. Nucleic Acids Res., 37, 2009
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4JOQ
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![BU of 4joq by Molmil](/molmil-images/mine/4joq) | Putative ribose ABC transporter, periplasmic solute-binding protein from Rhodobacter sphaeroides | Descriptor: | 1,2-ETHANEDIOL, ABC ribose transporter, periplasmic solute-binding protein, ... | Authors: | Osipiuk, J, Tesar, C, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-03-18 | Release date: | 2013-04-10 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Putative ribose ABC transporter, periplasmic solute-binding protein from Rhodobacter sphaeroides. To be Published
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2HEH
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![BU of 2heh by Molmil](/molmil-images/mine/2heh) | Crystal Structure of the KIF2C motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KIF2C protein, MAGNESIUM ION, ... | Authors: | Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-21 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the kif2c motor domain to be published
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4NQ8
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![BU of 4nq8 by Molmil](/molmil-images/mine/4nq8) | Crystal structure of a trap periplasmic solute binding protein from Bordetella bronchispeptica (bb3421), target EFI-510039, with density modeled as pantoate | Descriptor: | CHLORIDE ION, PANTOATE, Putative periplasmic substrate-binding transport protein, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-11-24 | Release date: | 2014-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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3MRF
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![BU of 3mrf by Molmil](/molmil-images/mine/3mrf) | Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide T4P variant | Descriptor: | 9-meric peptide from mRNA export factor EB2, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Trudel, E, Gras, S, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | Deposit date: | 2010-04-29 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide T4P variant To be Published
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3GG7
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![BU of 3gg7 by Molmil](/molmil-images/mine/3gg7) | Crystal structure of an uncharacterized metalloprotein from Deinococcus radiodurans | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, MANGANESE (II) ION, ... | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Tang, B.K, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-02-27 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of an uncharacterized metalloprotein from Deinococcus radiodurans To be Published
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3MKS
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![BU of 3mks by Molmil](/molmil-images/mine/3mks) | Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2 | Descriptor: | 1,1'-binaphthalene-2,2'-dicarboxylic acid, Cell division control protein 4, GLYCEROL, ... | Authors: | Orlicky, S, Sicheri, F, Tyers, M, Tang, X. | Deposit date: | 2010-04-15 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat.Biotechnol., 28, 2010
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2O9J
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![BU of 2o9j by Molmil](/molmil-images/mine/2o9j) | Crystal structure of calcium atpase with bound magnesium fluoride and cyclopiazonic acid | Descriptor: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, MAGNESIUM ION, SODIUM ION, ... | Authors: | Young, H.S, Moncoq, K.A. | Deposit date: | 2006-12-13 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The molecular basis for cyclopiazonic Acid inhibition of the sarcoplasmic reticulum calcium pump. J.Biol.Chem., 282, 2007
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3G71
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![BU of 3g71 by Molmil](/molmil-images/mine/3g71) | Co-crystal structure of Bruceantin bound to the large ribosomal subunit | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... | Authors: | Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A. | Deposit date: | 2009-02-09 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J.Mol.Biol., 389, 2009
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4NLP
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![BU of 4nlp by Molmil](/molmil-images/mine/4nlp) | Poliovirus Polymerase - C290V Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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3MRM
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![BU of 3mrm by Molmil](/molmil-images/mine/3mrm) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1406-1415 decapeptide | Descriptor: | 10-meric peptide from Genome polyprotein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Gras, S, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | Deposit date: | 2010-04-29 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1406-1415 decapeptide To be Published
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4NLX
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![BU of 4nlx by Molmil](/molmil-images/mine/4nlx) | Poliovirus Polymerase - G289A/C290V Loop Mutant | Descriptor: | ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... | Authors: | Sholders, A.J, Peersen, O.B. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
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3GGS
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![BU of 3ggs by Molmil](/molmil-images/mine/3ggs) | Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with 2-fluoro-2'-deoxyadenosine | Descriptor: | 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, Purine nucleoside phosphorylase, SULFATE ION | Authors: | Sawaya, M.R, Afshar, S. | Deposit date: | 2009-03-02 | Release date: | 2009-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Sci., 18, 2009
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4JRT
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![BU of 4jrt by Molmil](/molmil-images/mine/4jrt) | Crystal structure of an A-form RNA duplex containing three GU base pairs | Descriptor: | RNA (5'-R(P*CP*CP*UP*GP*CP*AP*CP*UP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*UP*GP*GP*UP*GP*CP*GP*GP*G)-3') | Authors: | Kondo, J, Dock-Bregeon, A.C, Willkomm, D.K, Hartmann, R.K, Westhof, E. | Deposit date: | 2013-03-21 | Release date: | 2013-06-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet Acta Crystallogr.,Sect.F, 69, 2013
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4NMD
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4NO2
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![BU of 4no2 by Molmil](/molmil-images/mine/4no2) | Crystal structure of RQA_V phosphopeptide bound to HLA-A2 | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Mohammed, F, Stones, D.H, Willcox, B.E. | Deposit date: | 2013-11-19 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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