3QGG
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![BU of 3qgg by Molmil](/molmil-images/mine/3qgg) | Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide | Descriptor: | (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, RNA-directed RNA polymerase, ... | Authors: | Sheriff, S. | Deposit date: | 2011-01-24 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
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1RDG
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4MBG
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![BU of 4mbg by Molmil](/molmil-images/mine/4mbg) | Crystal structure of Aspergillus fumigatus protein farnesyltransferase binary complex with farnesyldiphosphate | Descriptor: | 1,2-ETHANEDIOL, CaaX farnesyltransferase alpha subunit Ram2, CaaX farnesyltransferase beta subunit Ram1, ... | Authors: | Mabanglo, M.F, Hast, M.A, Beese, L.S. | Deposit date: | 2013-08-19 | Release date: | 2014-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. Protein Sci., 23, 2014
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3QGD
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![BU of 3qgd by Molmil](/molmil-images/mine/3qgd) | Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide | Descriptor: | (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide, RNA-directed RNA polymerase, ... | Authors: | Sheriff, S. | Deposit date: | 2011-01-24 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
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1QWO
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![BU of 1qwo by Molmil](/molmil-images/mine/1qwo) | Crystal structure of a phosphorylated phytase from Aspergillus fumigatus, revealing the structural basis for its heat resilience and catalytic pathway | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, phytase | Authors: | Xiang, T, Liu, Q, Deacon, A.M, Koshy, M, Kriksunov, I.A, Lei, X.G, Hao, Q, Thiel, D.J. | Deposit date: | 2003-09-03 | Release date: | 2004-06-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of a Heat-resilient Phytase from Aspergillus fumigatus, Carrying a Phosphorylated Histidine J.Mol.Biol., 339, 2004
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1W9V
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![BU of 1w9v by Molmil](/molmil-images/mine/1w9v) | Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus | Descriptor: | ARGIFIN, CHITINASE, SULFATE ION | Authors: | Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F. | Deposit date: | 2004-10-19 | Release date: | 2005-01-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12, 2005
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1E5D
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![BU of 1e5d by Molmil](/molmil-images/mine/1e5d) | RUBREDOXIN OXYGEN:OXIDOREDUCTASE (ROO) FROM ANAEROBE DESULFOVIBRIO GIGAS | Descriptor: | FLAVIN MONONUCLEOTIDE, MU-OXO-DIIRON, OXYGEN MOLECULE, ... | Authors: | Frazao, C, Silva, G, Gomes, C.M, Matias, P, Coelho, R, Sieker, L, Macedo, S, Liu, M.Y, Oliveira, S, Teixeira, M, Xavier, A.V, Rodrigues-Pousada, C, Carrondo, M.A, Le Gall, J. | Deposit date: | 2000-07-24 | Release date: | 2000-11-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a Dioxygen Reduction Enzyme from Desulfovibrio Gigas Nat.Struct.Biol., 7, 2000
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1W9U
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![BU of 1w9u by Molmil](/molmil-images/mine/1w9u) | Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against Aspergillus fumigatus chitinase | Descriptor: | ARGADIN, CHITINASE, SULFATE ION | Authors: | Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F. | Deposit date: | 2004-10-19 | Release date: | 2004-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12, 2005
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1W9P
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![BU of 1w9p by Molmil](/molmil-images/mine/1w9p) | Specificity and affinity of natural product cyclopentapeptide inhibitors against Aspergillus fumigatus, human and bacterial chitinaseFra | Descriptor: | CHITINASE, SULFATE ION | Authors: | Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, Van Aalten, D.M.F. | Deposit date: | 2004-10-15 | Release date: | 2004-10-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12, 2005
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5UBM
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![BU of 5ubm by Molmil](/molmil-images/mine/5ubm) | Crystal structure of human C1s in complex with inhibitor gigastasin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1s subcomponent, Gigastasin | Authors: | Pang, S.S, Whisstock, J.C. | Deposit date: | 2016-12-20 | Release date: | 2017-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech. J. Immunol., 199, 2017
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1WNO
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![BU of 1wno by Molmil](/molmil-images/mine/1wno) | Crystal structure of a native chitinase from Aspergillus fumigatus YJ-407 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase, ... | Authors: | Hu, H, Wang, G, Yang, H, Zhou, J, Mo, L, Yang, K, Jin, C, Jin, C, Rao, Z. | Deposit date: | 2004-08-07 | Release date: | 2005-03-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a native chitinase from Aspergillus fumigatus YJ-407 To be Published
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4QNW
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4JC1
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1KKC
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![BU of 1kkc by Molmil](/molmil-images/mine/1kkc) | Crystal structure of Aspergillus fumigatus MnSOD | Descriptor: | MANGANESE (II) ION, Manganese Superoxide Dismutase | Authors: | Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R. | Deposit date: | 2001-12-07 | Release date: | 2001-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. J.Immunol., 168, 2002
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1DM0
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![BU of 1dm0 by Molmil](/molmil-images/mine/1dm0) | SHIGA TOXIN | Descriptor: | SHIGA TOXIN A SUBUNIT, SHIGA TOXIN B SUBUNIT | Authors: | Fraser, M.E, Chernaia, M.M, Kozlov, Y.V, James, M.N. | Deposit date: | 1999-12-13 | Release date: | 1999-12-30 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution. Nat.Struct.Biol., 1, 1994
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5TUP
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![BU of 5tup by Molmil](/molmil-images/mine/5tup) | X-ray Crystal Structure of the Aspergillus fumigatus Sliding Clamp | Descriptor: | Proliferating cell nuclear antigen | Authors: | Bruning, J.B, Marshall, A.C, Kroker, A.J, Wegener, K.L, Rajapaksha, H. | Deposit date: | 2016-11-06 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21. FEBS J., 284, 2017
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3GYX
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![BU of 3gyx by Molmil](/molmil-images/mine/3gyx) | Crystal structure of adenylylsulfate reductase from Desulfovibrio gigas | Descriptor: | Adenylylsulfate Reductase, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER | Authors: | Chiang, Y.-L, Hsieh, Y.-C, Liu, E.-H, Liu, M.-Y, Chen, C.-J. | Deposit date: | 2009-04-06 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of Adenylylsulfate reductase from Desulfovibrio gigas suggests a potential self-regulation mechanism involving the C terminus of the beta-subunit J.Bacteriol., 191, 2009
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1SK9
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![BU of 1sk9 by Molmil](/molmil-images/mine/1sk9) | Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A, PHOSPHATE ION | Authors: | Liu, Q, Huang, Q, Lei, X.G, Hao, Q. | Deposit date: | 2004-03-04 | Release date: | 2004-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics Structure, 12, 2004
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4JUU
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![BU of 4juu by Molmil](/molmil-images/mine/4juu) | Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand | Descriptor: | CHLORIDE ION, Epimerase, PHOSPHATE ION, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-03-25 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of a putative hydroxyproline epimerase from xanthomonas campestris (TARGET EFI-506516) with bound phosphate and unknown ligand To be Published
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1SKA
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![BU of 1ska by Molmil](/molmil-images/mine/1ska) | Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A | Authors: | Liu, Q, Huang, Q, Lei, X.G, Hao, Q. | Deposit date: | 2004-03-04 | Release date: | 2004-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics Structure, 12, 2004
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2H9X
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![BU of 2h9x by Molmil](/molmil-images/mine/2h9x) | NMR structure for the CgNa toxin from the sea anemone Condylactis gigantea | Descriptor: | Toxin CgNa | Authors: | Lopez-Mendez, B, Perez-Castells, J, Gimenez-Gallego, G, Jimenez-Barbero, J. | Deposit date: | 2006-06-12 | Release date: | 2007-06-05 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | CgNa, a type I toxin from the giant Caribbean sea anemone Condylactis gigantea shows structural similarities to both type I and II toxins, as well as distinctive structural and functional properties(1). Biochem.J., 406, 2007
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3FC0
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![BU of 3fc0 by Molmil](/molmil-images/mine/3fc0) | 1.8 A crystal structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells | Descriptor: | ACETATE ION, GITR ligand | Authors: | Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | Deposit date: | 2008-11-20 | Release date: | 2008-12-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | 1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells. Acta Crystallogr.,Sect.D, 65, 2009
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5UQO
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1SK8
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![BU of 1sk8 by Molmil](/molmil-images/mine/1sk8) | Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A, PHOSPHATE ION | Authors: | Liu, Q, Huang, Q.Q, Lei, X.G, Hao, Q. | Deposit date: | 2004-03-04 | Release date: | 2005-02-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics Structure, 12, 2004
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1SKB
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![BU of 1skb by Molmil](/molmil-images/mine/1skb) | Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A | Authors: | Liu, Q, Huang, Q, Lei, X.G, Hao, Q. | Deposit date: | 2004-03-04 | Release date: | 2004-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics Structure, 12, 2004
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