2NDP
 
 | | Structure of DNA-binding HU protein from micoplasma Mycoplasma gallisepticum | | Descriptor: | Histone-like DNA-binding superfamily protein | | Authors: | Altukhov, D.A, Talyzina, A.A, Agapova, Y.K, Vlaskina, A.V, Korzhenevskiy, D.A, Bocharov, E.V, Rakitina, T.V, Timofeev, V.I, Popov, V.O. | | Deposit date: | 2016-09-13 | | Release date: | 2016-11-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Enhanced conformational flexibility of the histone-like (HU) protein from Mycoplasma gallisepticum.
J.Biomol.Struct.Dyn., 36, 2018
|
|
7TQN
 | |
7TQO
 | |
7TQP
 | | Structure of human TREX1 | | Descriptor: | SULFATE ION, Three-prime repair exonuclease 1 | | Authors: | Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. | | Deposit date: | 2022-01-26 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
|
|
5WX8
 | | Human herpesvirus 6A immediate early protein 2 C-terminal domain | | Descriptor: | Immediate-early protein 2 | | Authors: | Nishimura, M, Wang, J, Wakata, A, Sakamoto, K, Mori, Y. | | Deposit date: | 2017-01-06 | | Release date: | 2017-08-02 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2.
J. Virol., 91, 2017
|
|
6Z6E
 | | Crystal structure of the HK97 bacteriophage small terminase | | Descriptor: | IODIDE ION, Terminase small subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
|
|
3ON0
 | | Crystal structure of the pED208 TraM-sbmA complex | | Descriptor: | Protein traM, sbmA | | Authors: | Wong, J.J.W, Lu, J, Edwards, R.A, Frost, L.S, Mark Glover, J.N. | | Deposit date: | 2010-08-27 | | Release date: | 2011-05-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.874 Å) | | Cite: | Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM.
Nucleic Acids Res., 39, 2011
|
|
2LF7
 | |
2ME0
 | |
3IL2
 | |
5FW1
 | | Crystal structure of SpyCas9 variant VQR bound to sgRNA and TGAG PAM target DNA | | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | Authors: | Anders, C, Bargsten, K, Jinek, M. | | Deposit date: | 2016-02-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
|
|
7B4G
 | | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (II) | | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Degtjarik, O, Rozenberg, H, Shakked, Z. | | Deposit date: | 2020-12-02 | | Release date: | 2021-12-08 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ).
Nat Commun, 12, 2021
|
|
7UJN
 | | Structure of Human SAMHD1 with Non-Hydrolysable dGTP Analog | | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | | Authors: | Huynh, K.W, Ammirati, M, Han, S. | | Deposit date: | 2022-03-31 | | Release date: | 2022-07-20 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics.
Nucleic Acids Res., 50, 2022
|
|
5FW3
 | | Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA | | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | Authors: | Anders, C, Bargsten, K, Jinek, M. | | Deposit date: | 2016-02-11 | | Release date: | 2016-06-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
|
|
5FW2
 | | Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA | | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | Authors: | Anders, C, Bargsten, K, Jinek, M. | | Deposit date: | 2016-02-11 | | Release date: | 2016-06-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.676 Å) | | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
|
|
3IKT
 | |
4ZN1
 | | Crystal Structure of MjSpt4:Spt5 complex conformation A | | Descriptor: | Transcription elongation factor Spt4, Transcription elongation factor Spt5, ZINC ION | | Authors: | Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K. | | Deposit date: | 2015-05-04 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII
J.Struct.Biol., 192, 2015
|
|
2I9T
 | | Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter | | Descriptor: | 5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*CP*TP*G)-3', 5'-D(*CP*AP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*CP*T)-3', Nuclear factor NF-kappa-B p105 subunit, ... | | Authors: | Escalante, C.R, Shen, L, Thanos, D, Aggarwal, A.K. | | Deposit date: | 2006-09-06 | | Release date: | 2007-02-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
Structure, 10, 2002
|
|
3HIF
 | | The crystal structure of apo wild type CAP at 3.6 A resolution. | | Descriptor: | Catabolite gene activator | | Authors: | Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S. | | Deposit date: | 2009-05-19 | | Release date: | 2009-09-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
7O7B
 | |
8PVT
 | |
8PVZ
 | |
6Z6D
 | | Crystal structure of the HK97 bacteriophage large terminase | | Descriptor: | BROMIDE ION, Terminase large subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
|
|
2D1H
 | | Crystal structure of ST1889 protein from thermoacidophilic archaeon Sulfolobus tokodaii | | Descriptor: | 109aa long hypothetical transcriptional regulator | | Authors: | Shinkai, A, Sekine, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-08-22 | | Release date: | 2006-09-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The putative DNA-binding protein Sto12a from the thermoacidophilic archaeon Sulfolobus tokodaii contains intrachain and interchain disulfide bonds.
J.Mol.Biol., 372, 2007
|
|
7UFI
 | | VchTnsC AAA+ ATPase with DNA, single heptamer | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ... | | Authors: | Fernandez, I.S, Sternberg, S.H. | | Deposit date: | 2022-03-22 | | Release date: | 2022-06-08 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
|
|
