2GC8
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![BU of 2gc8 by Molmil](/molmil-images/mine/2gc8) | Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase | Descriptor: | 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE, RNA-directed RNA polymerase | Authors: | Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, K.J, Sukits, S.F, Svenson, K, Bard, J, Ellingboe, J.W, Agarwal, A, Krishnamurthy, G, Howe, A.Y, Orlowski, M, Feld, B, O'connell, J, Mansour, T.S. | Deposit date: | 2006-03-13 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site. J.Med.Chem., 49, 2006
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6LX2
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![BU of 6lx2 by Molmil](/molmil-images/mine/6lx2) | Potato D-enzyme complexed with CA26 | Descriptor: | 4-alpha-glucanotransferase, chloroplastic/amyloplastic, 4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose-(1-4)-4-deoxy-alpha-D-glucopyranose, ... | Authors: | Unno, H, Imamura, K. | Deposit date: | 2020-02-10 | Release date: | 2020-08-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
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2G8G
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![BU of 2g8g by Molmil](/molmil-images/mine/2g8g) | Structurally mapping the diverse phenotype of Adeno-Associated Virus serotype 4 | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid | Authors: | Govindasamy, L, Padron, E, McKenna, R, Muzyczka, N, Chiorini, J.A, Agbandje-McKenna, M. | Deposit date: | 2006-03-02 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. J.Virol., 80, 2006
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2GEZ
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![BU of 2gez by Molmil](/molmil-images/mine/2gez) | Crystal structure of potassium-independent plant asparaginase | Descriptor: | CHLORIDE ION, L-asparaginase alpha subunit, L-asparaginase beta subunit, ... | Authors: | Michalska, K, Bujacz, G, Jaskolski, M. | Deposit date: | 2006-03-21 | Release date: | 2006-07-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of plant asparaginase. J.Mol.Biol., 360, 2006
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2GA3
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![BU of 2ga3 by Molmil](/molmil-images/mine/2ga3) | |
2GAS
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![BU of 2gas by Molmil](/molmil-images/mine/2gas) | Crystal Structure of Isoflavone Reductase | Descriptor: | isoflavone reductase | Authors: | Wang, X, He, X, Lin, J, Shao, H, Chang, Z, Dixon, R.A. | Deposit date: | 2006-03-09 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.) J.Mol.Biol., 358, 2006
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2GB7
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![BU of 2gb7 by Molmil](/molmil-images/mine/2gb7) | Metal-depleted Ecl18kI in complex with uncleaved, modified DNA | Descriptor: | DNA STRAND 1, DNA STRAND 2, R.Ecl18kI | Authors: | Bochtler, M, Szczepanowski, R.H, Tamulaitis, G, Grazulis, S, Czapinska, H, Manakova, E, Siksnys, V. | Deposit date: | 2006-03-10 | Release date: | 2006-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease Embo J., 25, 2006
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2GHQ
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3V8X
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![BU of 3v8x by Molmil](/molmil-images/mine/3v8x) | The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Noinaj, N, Easley, N, Buchanan, S.K. | Deposit date: | 2011-12-23 | Release date: | 2012-02-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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2GIJ
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![BU of 2gij by Molmil](/molmil-images/mine/2gij) | Q138F HincII bound to cognate DNA GTTAAC and Ca2+ | Descriptor: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Horton, N.C, Joshi, H.K. | Deposit date: | 2006-03-28 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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2G46
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6M4E
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![BU of 6m4e by Molmil](/molmil-images/mine/6m4e) | Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Uehara, R, Iwamoto, R, Aoki, S, Yoshizawa, T, Takano, K, Matsumura, H, Tanaka, S.-i. | Deposit date: | 2020-03-06 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis. Protein Sci., 29, 2020
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2G81
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![BU of 2g81 by Molmil](/molmil-images/mine/2g81) | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with Beta-trypsin at 1.55 Angstrons Resolution | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Bowman-Birk type seed trypsin and chymotrypsin inhibitor, ... | Authors: | Freitas, S.M, Barbosa, J.A.R.G, Paulino, L.S, Teles, R.C.L, Esteves, G.F, Ventura, M.M. | Deposit date: | 2006-03-01 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with {beta}-Trypsin at 1.55 A Resolution and Its Structural Properties in Association with Proteinases Biophys.J., 92, 2007
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2G8C
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5A87
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![BU of 5a87 by Molmil](/molmil-images/mine/5a87) | Crystal structure of the metallo-beta-lactamase VIM-5 | Descriptor: | GLYCEROL, METALLO-BETA-LACTAMASE VIM-5, ZINC ION | Authors: | Brem, J, Duzgun, A.O, McDonough, M.A, Schofield, C.J. | Deposit date: | 2015-07-13 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Comparison of Verona Integron-Borne Metallo-beta-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles. Antimicrob. Agents Chemother., 60, 2015
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6M55
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![BU of 6m55 by Molmil](/molmil-images/mine/6m55) | Crystal structure of the E496A mutant of HsBglA in complex with 4-galactosyllactose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase-like enzyme, ... | Authors: | Uehara, R, Iwamoto, R, Aoki, S, Yoshizawa, T, Takano, K, Matsumura, H, Tanaka, S.-i. | Deposit date: | 2020-03-10 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis. Protein Sci., 29, 2020
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5AC7
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![BU of 5ac7 by Molmil](/molmil-images/mine/5ac7) | S. enterica HisA with mutations D7N, D10G, dup13-15 | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, GLYCEROL, SODIUM ION, ... | Authors: | Newton, M, Guo, X, Soderholm, A, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | Deposit date: | 2015-08-12 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2G8R
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![BU of 2g8r by Molmil](/molmil-images/mine/2g8r) | The crystal structure of the RNase A- 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine complex | Descriptor: | 1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARABINOFURANOSYL]PYRIMIDINE-2,4(1H,3H)-DIONE, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2006-03-03 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal. Bioorg.Med.Chem., 14, 2006
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7DO4
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![BU of 7do4 by Molmil](/molmil-images/mine/7do4) | Crystal structure of CD97-CD55 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Niu, M, Song, G. | Deposit date: | 2020-12-11 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs. J.Biol.Chem., 296, 2021
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2GCS
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5AHA
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![BU of 5aha by Molmil](/molmil-images/mine/5aha) | Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II) | Descriptor: | (3R,3aS,4R,6aR)-4-(2-methoxyethoxy)hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[(2Z)-2-(methylimino)-2,3-dihydro-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE | Authors: | Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J. | Deposit date: | 2015-02-05 | Release date: | 2015-05-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II). J.Med.Chem., 58, 2015
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2GCX
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![BU of 2gcx by Molmil](/molmil-images/mine/2gcx) | Solution Structure of Ferrous Iron Transport Protein A (FeoA) of Klebsiella pneumoniae | Descriptor: | Ferrous iron transport protein A | Authors: | Hung, K.-W, Cheng, C.-C, Yu, T.-H, Wang, S.-H, Chang, C.-F, Tsai, S.-F, Huang, T.-H. | Deposit date: | 2006-03-14 | Release date: | 2007-03-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of Ferrous Iron Transport Protein A (FeoA) of Klebsiella pneumoniae To be Published
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2GE2
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5A3B
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![BU of 5a3b by Molmil](/molmil-images/mine/5a3b) | Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with ADP-ribose | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, ALANINE, ... | Authors: | Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I. | Deposit date: | 2015-05-28 | Release date: | 2015-07-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens. Mol.Cell, 59, 2015
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5A2Y
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![BU of 5a2y by Molmil](/molmil-images/mine/5a2y) | Crystal structure of mtPAP in complex with UTP | Descriptor: | MAGNESIUM ION, MITOCHONDRIAL PROTEIN, URIDINE 5'-TRIPHOSPHATE | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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