5A87

Crystal structure of the metallo-beta-lactamase VIM-5

Summary for 5A87

• Entry DOI: 10.2210/pdb5a87/pdb
• Descriptor: METALLO-BETA-LACTAMASE VIM-5, GLYCEROL, ZINC ION, ... (4 entities in total)
• Functional Keywords: metallo-beta-lactamase, hydrolase, antibiotic resitance
• Biological source: KLEBSIELLA PNEUMONIAE
• Total number of polymer chains: 2
• Total formula weight: 52919.39

Authors

Brem, J.,Duzgun, A.O.,McDonough, M.A.,Schofield, C.J. (deposition date: 2015-07-13, release date: 2015-12-23, Last modification date: 2024-01-10)

• Primary citation: Makena, A.,Duzgun, A.O.,Brem, J.,McDonough, M.A.,Rydzik, A.M.,Abboud, M.I.,Saral, A.,Cicek, A.C.,Sandalli, C.,Schofield, C.J.; Comparison of Verona Integron-Borne Metallo-beta-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles.; Antimicrob. Agents Chemother., 60:1377-1384, 2015; PubMed: 26666919; DOI: 10.1128/AAC.01768-15

Experimental method

X-RAY DIFFRACTION (1.5 Å)