5A87

Crystal structure of the metallo-beta-lactamase VIM-5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0042597	cellular_component	periplasmic space
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0042597	cellular_component	periplasmic space
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1262

Chain	Residue
A	ASN210
A	HIS240
A	ZN1263
A	HOH2109
A	HOH2183
A	HOH2219

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1263

Chain	Residue
A	GOL1262
A	ZN1265
A	HOH2109
A	HIS114
A	HIS116
A	HIS179

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1264

Chain	Residue
A	SER136
A	LEU158
A	SER159
A	TYR174
A	ASP182
A	HOH2124

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1265

Chain	Residue
A	ASP118
A	CYS198
A	HIS240
A	ZN1263
A	HOH2109
A	HOH2167

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1266

Chain	Residue
A	ASP117
A	GLY147
A	ASN148
A	HOH2220

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 1262

Chain	Residue
B	HIS114
B	HIS116
B	HIS179
B	ZN1264
B	HOH2084

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 1263

Chain	Residue
B	GLY104
B	SER160
B	ASP163
B	HOH2069
B	HOH2125

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN B 1264

Chain	Residue
B	ASP118
B	CYS198
B	HIS240
B	ZN1262
B	HOH2084
B	HOH2142

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 1267

Chain	Residue
A	HIS153
A	HOH2221
A	HOH2222

---