1RU0
 
 | | Crystal structure of DCoH2, a paralog of DCoH, the Dimerization Cofactor of HNF-1 | | Descriptor: | DcoH-like protein DCoHm | | Authors: | Rose, R.B, Pullen, K.E, Bayle, J.H, Crabtree, G.R, Alber, T. | | Deposit date: | 2003-12-10 | | Release date: | 2004-10-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2
Biochemistry, 43, 2004
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1KCY
 | | NMR solution structure of apo calbindin D9k (F36G + P43M mutant) | | Descriptor: | calbindin D9k | | Authors: | Nelson, M.R, Thulin, E, Fagan, P.A, Forsen, S, Chazin, W.J. | | Deposit date: | 2001-11-12 | | Release date: | 2001-11-21 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The EF-hand domain: a globally cooperative structural unit.
Protein Sci., 11, 2002
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1L2Z
 | | CD2BP2-GYF domain in complex with proline-rich CD2 tail segment peptide | | Descriptor: | CD2 ANTIGEN (CYTOPLASMIC TAIL)-BINDING PROTEIN 2, T-CELL SURFACE ANTIGEN CD2 | | Authors: | Freund, C, Kuhne, R, Yang, H, Park, S, Reinherz, E.L, Wagner, G. | | Deposit date: | 2002-02-26 | | Release date: | 2002-11-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Embo J., 21, 2002
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4QR4
 | | Brd4 Bromodomain 1 complex with its novel inhibitors | | Descriptor: | 2-chloro-N-cyclopentyl-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide, Bromodomain-containing protein 4 | | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | | Deposit date: | 2014-06-30 | | Release date: | 2015-07-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization
J.Med.Chem., 58, 2015
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4QR3
 | | Brd4 Bromodomain 1 complex with its novel inhibitors | | Descriptor: | Bromodomain-containing protein 4, N-cyclopentyl-3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide | | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | | Deposit date: | 2014-06-30 | | Release date: | 2015-07-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.374 Å) | | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization
J.Med.Chem., 58, 2015
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4QR5
 | | Brd4 Bromodomain 1 complex with its novel inhibitors | | Descriptor: | Bromodomain-containing protein 4, N-[3-(cyclopentylsulfamoyl)-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]cyclopropanecarboxamide | | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | | Deposit date: | 2014-06-30 | | Release date: | 2015-07-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization
J.Med.Chem., 58, 2015
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5EKF
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5EKG
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2GWS
 | | Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus | | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', ... | | Authors: | Garcia-Diaz, M, Picher, A.J, Bebenek, K, Pedersen, L.C, Kunkel, T.A, Blanco, L. | | Deposit date: | 2006-05-05 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Promiscuous mismatch extension by human DNA polymerase lambda.
Nucleic Acids Res., 34, 2006
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2HQW
 | | Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide | | Descriptor: | CALCIUM ION, Calmodulin, Glutamate NMDA receptor subunit zeta 1 | | Authors: | Akyol, Z, Gakhar, L, Sorensen, B.R, Hell, J.H, Shea, M.A. | | Deposit date: | 2006-07-19 | | Release date: | 2007-11-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains.
Structure, 15, 2007
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2JOR
 | | NMR Solution Structure, Stability, and Interaction of the Recombinant Bovine Fibrinogen alphaC-Domain Fragment | | Descriptor: | Fibrinogen alpha chain | | Authors: | Burton, R.A, Tsurupa, G, Roy, H, Nico, T, Leonid, M. | | Deposit date: | 2007-03-20 | | Release date: | 2007-08-07 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure, Stability, and Interaction of the Recombinant Bovine Fibrinogen alphaC-Domain Fragment
Biochemistry, 46, 2007
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3VBJ
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5FXT
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4EAH
 | | Crystal structure of the formin homology 2 domain of FMNL3 bound to actin | | Descriptor: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Thompson, M.E, Heimsath, E.G, Gauvin, T.J, Higgs, H.N, Kull, F.J. | | Deposit date: | 2012-03-22 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | FMNL3 FH2-actin structure gives insight into formin-mediated actin nucleation and elongation.
Nat.Struct.Mol.Biol., 20, 2013
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5C7I
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3X1V
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4NRV
 | | Crystal Structure of non-edited human NEIL1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endonuclease 8-like 1 | | Authors: | Prakash, A, Doublie, S. | | Deposit date: | 2013-11-27 | | Release date: | 2014-01-01 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing.
Dna Repair, 14, 2014
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2CA6
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4E46
 | | Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol | | Descriptor: | ACETATE ION, CHLORIDE ION, Haloalkane dehalogenase, ... | | Authors: | Stsiapanava, A, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I. | | Deposit date: | 2012-03-12 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents.
Chembiochem, 14, 2013
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2M8D
 | | Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3' | | Descriptor: | RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1 | | Authors: | Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T. | | Deposit date: | 2013-05-17 | | Release date: | 2013-07-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6PYA
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6PYF
 | | Sex Hormone-binding globulin mutant E176K in complex with Estradiol | | Descriptor: | CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin | | Authors: | Round, P.W, Wu, T.S, Das, S, Van Petegem, F. | | Deposit date: | 2019-07-29 | | Release date: | 2019-12-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
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6PYB
 | | Sex Hormone-binding globulin mutant E176K in complex with DVT | | Descriptor: | 4,4'-[(3R,4R)-oxolane-3,4-diylbis(methylene)]bis(2-methoxyphenol), CALCIUM ION, Sex hormone-binding globulin | | Authors: | Round, P.W, Das, S, Van Petegem, F. | | Deposit date: | 2019-07-29 | | Release date: | 2019-12-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
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3FZW
 | | Crystal Structure of Ketosteroid Isomerase D40N-D103N from Pseudomonas putida (pKSI) with bound equilenin | | Descriptor: | EQUILENIN, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Caaveiro, J.M.M, Ringe, D, Petsko, G.A. | | Deposit date: | 2009-01-26 | | Release date: | 2009-06-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | Hydrogen bond coupling in the ketosteroid isomerase active site.
Biochemistry, 48, 2009
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2FPP
 | | Crystal structure of pig GTP-specific succinyl-CoA synthetase from polyethylene glycol with chloride ions | | Descriptor: | CHLORIDE ION, SULFATE ION, Succinyl-CoA ligase [GDP-forming] alpha-chain, ... | | Authors: | Fraser, M.E, Hayakawa, K, Hume, M.S, Ryan, D.G, Brownie, E.R. | | Deposit date: | 2006-01-16 | | Release date: | 2006-02-21 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Interactions of GTP with the ATP-grasp Domain of GTP-specific Succinyl-CoA Synthetase
J.Biol.Chem., 281, 2006
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