6QXA
| Structure of membrane bound pyrophosphatase from Thermotoga maritima in complex with imidodiphosphate and N-[(2-amino-6-benzothiazolyl)methyl]-1H-indole-2-carboxamide (ATC) | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, IMIDODIPHOSPHORIC ACID, K(+)-stimulated pyrophosphate-energized sodium pump, ... | Authors: | Vidilaseris, K, Goldman, A. | Deposit date: | 2019-03-07 | Release date: | 2019-04-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Asymmetry in catalysis byThermotoga maritimamembrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor. Sci Adv, 5, 2019
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6S4J
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6S4I
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6LDI
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6M6Z
| A de novo designed transmembrane nanopore, TMH4C4 | Descriptor: | TMH4C4 | Authors: | Lu, P, Xu, C, Reggiano, G, Xu, Q, DiMaio, F, Baker, D. | Deposit date: | 2020-03-16 | Release date: | 2020-06-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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6MIE
| Solution NMR structure of the KCNQ1 voltage-sensing domain | Descriptor: | Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R. | Deposit date: | 2018-09-19 | Release date: | 2020-03-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, 2020
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2XNH
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2XNK
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329D
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1JO6
| Solution structure of the cytoplasmic N-terminus of the BK beta-subunit KCNMB2 | Descriptor: | potassium large conductance calcium-activated channel, subfamily M, beta member 2 | Authors: | Bentrop, D, Beyermann, M, Wissmann, R, Fakler, B. | Deposit date: | 2001-07-27 | Release date: | 2001-11-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channels. J.Biol.Chem., 276, 2001
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2ZGV
| Crystal Structure of human phosphoglycerate kinase bound to D-ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphoglycerate kinase 1 | Authors: | Arold, S.T, Gondeau, C, Lionne, C, Chaloin, L. | Deposit date: | 2008-01-26 | Release date: | 2008-07-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase Nucleic Acids Res., 36, 2008
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1KN7
| Solution structure of the tandem inactivation domain (residues 1-75) of potassium channel RCK4 (Kv1.4) | Descriptor: | VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV1.4 | Authors: | Wissmann, R, Bildl, W, Oliver, D, Beyermann, M, Kalbitzer, H.R, Bentrop, D, Fakler, B. | Deposit date: | 2001-12-18 | Release date: | 2003-05-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Function of the "Tandem Inactivation Domain" of the Neuronal A-type
Potassium Channel Kv1.4 J.Biol.Chem., 278, 2003
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1KXP
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1KW2
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1HK7
| Middle Domain of HSP90 | Descriptor: | CADMIUM ION, HEAT SHOCK PROTEIN HSP82, MAGNESIUM ION | Authors: | Meyer, P, Prodromou, C, Roe, S.M, Pearl, L.H. | Deposit date: | 2003-03-06 | Release date: | 2004-01-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Functional Analysis of the Middle Segment of Hsp90. Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions Mol.Cell, 11, 2003
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1ISQ
| Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide | Descriptor: | Proliferating Cell Nuclear Antigen, replication factor C large subunit | Authors: | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | Deposit date: | 2001-12-19 | Release date: | 2002-10-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Physical interaction between proliferating cell nuclear antigen and
replication factor C from Pyrococcus furiosus Genes Cells, 7, 2002
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2ZD9
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3BEH
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3BDL
| Crystal structure of a truncated human Tudor-SN | Descriptor: | CITRIC ACID, Staphylococcal nuclease domain-containing protein 1 | Authors: | Li, C.L. | Deposit date: | 2007-11-15 | Release date: | 2008-08-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing. Nucleic Acids Res., 36, 2008
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3C39
| Crystal Structure of human phosphoglycerate kinase bound to 3-phosphoglycerate | Descriptor: | 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1 | Authors: | Arold, S.T, Gondeau, C, Lionne, C, Chaloin, L. | Deposit date: | 2008-01-28 | Release date: | 2008-07-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase Nucleic Acids Res., 36, 2008
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8C0D
| UFL1/DDRGK1 bound to UFC1 | Descriptor: | DDRGK domain-containing protein 1, E3 UFM1-protein ligase 1, Ubiquitin-fold modifier-conjugating enzyme 1 | Authors: | Magnussen, H.M, Kulathu, Y. | Deposit date: | 2022-12-16 | Release date: | 2023-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.564 Å) | Cite: | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
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8BZR
| UFC1-UFM1 conjugate | Descriptor: | 1,2-ETHANEDIOL, Ubiquitin-fold modifier 1, Ubiquitin-fold modifier-conjugating enzyme 1 | Authors: | Magnussen, H.M, Kulathu, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
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1MW8
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8CRO
| Cryo-EM structure of Pyrococcus furiosus transcription elongation complex | Descriptor: | DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... | Authors: | Tarau, D.M, Grunberger, F, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | Deposit date: | 2023-03-08 | Release date: | 2024-04-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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7C2M
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with NITD-349 | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Chimera of drug exporters of the RND superfamily-like protein and Endolysin, N-(4,4-dimethylcyclohexyl)-4,6-bis(fluoranyl)-1H-indole-2-carboxamide, ... | Authors: | Zhang, B, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-05-08 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. J.Mol.Biol., 432, 2020
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