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8H9X
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BU of 8h9x by Molmil
Crystal structure of voltage-gated sodium channel NavAb N49K/L176Q mutant in sodium ion condition
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Irie, K, Oda, Y.
Deposit date:2022-10-25
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel.
Nat Commun, 14, 2023
8HA1
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BU of 8ha1 by Molmil
Crystal structure of voltage-gated sodium channel NavAb N49K/L176G mutant in sodium ion condition
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Irie, K, Oda, Y.
Deposit date:2022-10-26
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel.
Nat Commun, 14, 2023
1NNW
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BU of 1nnw by Molmil
hypothetical protein from Pyrococcus furiosus Pfu-1218608
Descriptor: PLATINUM (II) ION, SODIUM ION, hypothetical protein
Authors:Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-01-14
Release date:2003-02-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Southeast Collaboratory for Structural Genomics: hypothetical protein from Pyrococcus furiosus Pfu-1218608
To be published
8OG2
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BU of 8og2 by Molmil
Crystal structure of CREBBP histone acetyltransferase domain in complex with Coenzyme A
Descriptor: COENZYME A, SODIUM ION, SULFATE ION, ...
Authors:Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
Deposit date:2023-03-17
Release date:2024-04-03
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal structure of CREBBP histone acetyltransferase domain in complex with Coenzyme A
To Be Published
7P9Q
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BU of 7p9q by Molmil
Crystal structure of Indole 3-Carboxylic acid decarboxylase from Arthrobacter nicotianae FI1612 in complex with co-factor prFMN.
Descriptor: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, AnInD, MANGANESE (II) ION, ...
Authors:Gahloth, D, Leys, D.
Deposit date:2021-07-27
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural and biochemical characterization of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase.
J.Biol.Chem., 298, 2022
8OIO
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BU of 8oio by Molmil
Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Kelch-like protein 12, ...
Authors:Dalietou, E.V, Chen, Z, Ramdass, A.E, Manning, C, Richardson, W, Aitmakhanova, K, Platt, M, Pike, A.C.W, Fedorov, O, Brennan, P, Bullock, A.N.
Deposit date:2023-03-23
Release date:2024-04-03
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide
To Be Published
7P3I
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BU of 7p3i by Molmil
Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 DARPin protein
Descriptor: Darpin, SODIUM ION, Tumor necrosis factor receptor superfamily member 5
Authors:Malvezzi, F, Mangold, S, Hospodarsch, T, Reichen, C, Iss, C, Lammens, A, Krapp, S, Domke, C.
Deposit date:2021-07-07
Release date:2022-04-06
Last modified:2022-05-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression.
Cancer Immunol Res, 10, 2022
8H1G
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BU of 8h1g by Molmil
The R406T mutant form of the Aquifex aeolicus MutL endonuclease domain
Descriptor: CADMIUM ION, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL, ...
Authors:Fukui, K, Yano, T.
Deposit date:2022-10-03
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Catalytic mechanism of the zinc-dependent MutL endonuclease reaction.
Life Sci Alliance, 6, 2023
7OV8
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BU of 7ov8 by Molmil
Crystal structure of pig purple acid phosphatase in complex with 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) and glycerol
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Feder, D, McGeary, R.P, Guddat, L.W, Schenk, G.
Deposit date:2021-06-14
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach.
Chemmedchem, 16, 2021
7P0X
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BU of 7p0x by Molmil
Crystal structure of Thioredoxin reductase from Brugia Malayi
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Cheng, Q, Arner, E.S.J, Williams, D.L.
Deposit date:2021-06-30
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.
Redox Biol, 51, 2022
7P0V
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BU of 7p0v by Molmil
Crystal structure of human SF3A1 ubiquitin-like domain in complex with U1 snRNA stem-loop 4
Descriptor: Isoform 2 of Splicing factor 3A subunit 1, PENTAETHYLENE GLYCOL, RNA (5'-R(P*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3'), ...
Authors:Sabath, K, de Vries, T, Jonas, S.
Deposit date:2021-06-30
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022
8HHV
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BU of 8hhv by Molmil
endo-alpha-D-arabinanase EndoMA1 from Microbacterium arabinogalactanolyticum
Descriptor: CALCIUM ION, GLYCEROL, SODIUM ION, ...
Authors:Nakashima, C, Li, J, Arakawa, T, Yamada, C, Ishiwata, A, Fujita, K, Fushinobu, S.
Deposit date:2022-11-17
Release date:2023-08-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
Nat Commun, 14, 2023
8JZB
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BU of 8jzb by Molmil
Langya Henipavirus attachment protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
Authors:Yan, R.H, Guo, Y.Y.
Deposit date:2023-07-05
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:A special homotetrameric architecture of langya virus glycoprotein
To Be Published
1ND4
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BU of 1nd4 by Molmil
Crystal structure of aminoglycoside-3'-phosphotransferase-IIa
Descriptor: ACETATE ION, Aminoglycoside 3'-phosphotransferase, KANAMYCIN A, ...
Authors:Nurizzo, D, Shewry, S.C, Baker, E.N, Smith, C.A.
Deposit date:2002-12-06
Release date:2003-09-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance
J.Mol.Biol., 327, 2003
7P0D
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BU of 7p0d by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER 310 MPA PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7P0G
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BU of 7p0g by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER AMBIENT PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
6NYP
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BU of 6nyp by Molmil
Crystal structure of UL144/BTLA complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B- and T-lymphocyte attenuator, GLYCEROL, ...
Authors:Aruna, B, Zajonc, D.M, Doukov, T.
Deposit date:2019-02-11
Release date:2019-05-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator.
J.Biol.Chem., 294, 2019
7P0C
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BU of 7p0c by Molmil
URATE OXIDASE WITH 8-AZAXANTHINE UNDER 210 MPA PRESSURE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T, Girard, E.
Deposit date:2021-06-29
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization
Acta Cryst. D, 78, 2022
7OPZ
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BU of 7opz by Molmil
Camel GSTM1-1 in complex with glutathione
Descriptor: GLUTATHIONE, Glutathione transferase, SODIUM ION
Authors:Papageorgiou, A.C, Poudel, N.
Deposit date:2021-06-02
Release date:2022-02-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and Functional Characterization of Camelus dromedarius Glutathione Transferase M1-1.
Life, 12, 2022
7OPY
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BU of 7opy by Molmil
Camel GSTM1-1 in complex with S-(p-nitrobenzyl)glutathione
Descriptor: FORMIC ACID, Glutathione transferase, S-(P-NITROBENZYL)GLUTATHIONE, ...
Authors:Papageorgiou, A.C, Poudel, N.
Deposit date:2021-06-02
Release date:2022-02-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Functional Characterization of Camelus dromedarius Glutathione Transferase M1-1.
Life, 12, 2022
8FD7
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BU of 8fd7 by Molmil
Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin
Descriptor: (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, Z, Mondal, A, Minor, D.L.
Deposit date:2022-12-02
Release date:2023-03-22
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for Ca V alpha 2 delta :gabapentin binding.
Nat.Struct.Mol.Biol., 30, 2023
7O1U
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BU of 7o1u by Molmil
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 1 (BEV241)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O, Brandstetter, H.
Deposit date:2021-03-30
Release date:2021-09-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:OFF-State-Specific Inhibition of the Proprotein Convertase Furin.
Acs Chem.Biol., 16, 2021
7O22
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BU of 7o22 by Molmil
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (mi359)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O, Brandstetter, H.
Deposit date:2021-03-30
Release date:2021-09-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:OFF-State-Specific Inhibition of the Proprotein Convertase Furin.
Acs Chem.Biol., 16, 2021
7O1Y
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BU of 7o1y by Molmil
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 0.25 M NaCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Dahms, S.O, Brandstetter, H.
Deposit date:2021-03-30
Release date:2021-09-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:OFF-State-Specific Inhibition of the Proprotein Convertase Furin.
Acs Chem.Biol., 16, 2021
8FVW
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BU of 8fvw by Molmil
CryoEM structure of E.coli transcription elongation complex bound to ppGpp
Descriptor: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Duan, W, Serganov, A.
Deposit date:2023-01-19
Release date:2023-04-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Control of transcription elongation and DNA repair by alarmone ppGpp.
Nat.Struct.Mol.Biol., 30, 2023

222624

数据于2024-07-17公开中

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