6H66
| CryoEM structure of the MDA5-dsRNA filament with 93 degree twist and without nucleotide | Descriptor: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-07-26 | Release date: | 2018-11-21 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
|
|
4XBF
| Structure of LSD1:CoREST in complex with ssRNA | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | Authors: | Luka, Z, Loukachevitch, L.V, Martin, W.J, Wagner, C, Reiter, N.J. | Deposit date: | 2014-12-16 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme. RNA, 22, 2016
|
|
6GKH
| CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-05-21 | Release date: | 2018-11-21 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
|
|
6GKM
| CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-05-21 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
|
|
6H61
| CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide | Descriptor: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-07-25 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.02 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
|
|
6GJZ
| CryoEM structure of the MDA5-dsRNA filament in complex with AMPPNP | Descriptor: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-05-17 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
|
|
6J7Z
| Human mitochondrial Oligoribonuclease in complex with RNA | Descriptor: | CITRIC ACID, MAGNESIUM ION, Oligoribonuclease, ... | Authors: | Chu, L.Y, Agrawal, S, Yuan, H.S. | Deposit date: | 2019-01-18 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Structural insights into nanoRNA degradation by human Rexo2. Rna, 25, 2019
|
|
4JKG
| Open and closed forms of mixed T1789P+R1865A and R1865A human PRP8 RNase H-like domain with bound Mg ion | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | Authors: | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | Deposit date: | 2013-03-09 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
7YFY
| Cryo-EM structure of the Mili-piRNA- target ternary complex | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-09 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7PMQ
| |
7PLI
| DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Wurm, J.P. | Deposit date: | 2021-08-31 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA. Rna, 29, 2023
|
|
398D
| 3'-DNA-RNA-5' JUNCTION FORMED DURING INITIATION OF MINUS-STRAND SYNTHESIS OF HIV REPLICATION | Descriptor: | DNA/RNA (5'-R(*GP*CP*CP*AP)-D(*CP*TP*GP*C)-3'), RNA (5'-R(*GP*CP*AP*GP*UP*GP*GP*C)-3') | Authors: | Mueller, U, Meier, G, Mochi-Onori, A, Cellai, L, Heumann, H. | Deposit date: | 1998-05-04 | Release date: | 1998-10-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of an eight-base pair duplex containing the 3'-DNA-RNA-5' junction formed during initiation of minus-strand synthesis of HIV replication. Biochemistry, 37, 1998
|
|
7LFQ
| Pyrococcus RNA ligase | Descriptor: | DNA (5'-D(*AP*TP*GP*TP*CP*C)-3'), POTASSIUM ION, RNA-splicing ligase RtcB, ... | Authors: | Goldgur, Y, Shuman, S, Banerjee, A. | Deposit date: | 2021-01-18 | Release date: | 2021-03-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of 3'-PO 4 /5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide. Rna, 27, 2021
|
|
6FQR
| |
7YPW
| Lloviu cuevavirus nucleoprotein-RNA complex | Descriptor: | Nucleoprotein, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3') | Authors: | Hu, S.F, Fujita-Fujiharu, Y, Sugita, Y, Wendt, L, Muramoto, Y, Nakano, M, Hoenen, T, Noda, T. | Deposit date: | 2022-08-04 | Release date: | 2023-04-19 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.0356 Å) | Cite: | Cryoelectron microscopic structure of the nucleoprotein-RNA complex of the European filovirus, Lloviu virus. Pnas Nexus, 2, 2023
|
|
5IPP
| |
7VW3
| Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ... | Authors: | Du, W.H, Qian, J.Q, Huang, Q. | Deposit date: | 2021-11-09 | Release date: | 2023-03-15 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State. Int J Mol Sci, 24, 2023
|
|
3HL2
| The crystal structure of the human SepSecS-tRNASec complex | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Monothiophosphate, O-phosphoseryl-tRNA(Sec) selenium transferase, ... | Authors: | Palioura, S, Steitz, T.A, Soll, D, Simonovic, M. | Deposit date: | 2009-05-26 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation. Science, 325, 2009
|
|
1O0B
| |
2KGP
| Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone) | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER) | Authors: | Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G. | Deposit date: | 2009-03-13 | Release date: | 2009-06-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). Chem.Biol., 16, 2009
|
|
1O0C
| |
1MHK
| Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn | Descriptor: | BROMIDE ION, RNA 12-mer BCh12, RNA 14-mer BCh12 | Authors: | Szep, S, Wang, J, Moore, P.B. | Deposit date: | 2002-08-20 | Release date: | 2002-09-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of a 26-nucleotide RNA containing a hook-turn RNA, 9, 2003
|
|
4JK8
| Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Mg ion | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | Deposit date: | 2013-03-09 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JKE
| Open and closed forms of T1789P human PRP8 RNase H-like domain with bound Mg ion | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | Authors: | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | Deposit date: | 2013-03-09 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JKF
| Open and closed forms of T1791P+R1865A human PRP8 RNase H-like domain with bound Mg ion | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | Authors: | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | Deposit date: | 2013-03-09 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|