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4HTP
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Crystal structure of the DBD domain of human DNA ligase IV bound to Artemis peptide
Descriptor: DNA ligase 4, Protein artemis
Authors:De Ioannes, P.E, Aggarwal, A.K.
Deposit date:2012-11-01
Release date:2012-12-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.2502 Å)
Cite:Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining.
Cell Rep, 2, 2012
2D4U
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BU of 2d4u by Molmil
Crystal Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr
Descriptor: Methyl-accepting chemotaxis protein I
Authors:Imada, K, Tajima, H, Namba, K, Sakuma, M, Homma, M, Kawagishi, I.
Deposit date:2005-10-24
Release date:2006-11-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ligand specificity determined by differentially arranged common ligand-binding residues in the bacterial amino acid chemoreceptors Tsr and Tar.
J.Biol.Chem., 2011
1I8E
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BU of 1i8e by Molmil
NMR ENSEMBLE OF ION-SELECTIVE LIGAND A22 FOR PLATELET INTEGRIN ALPHAIIB-BETA3
Descriptor: ION-SELECTIVE LIGAND A22
Authors:Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N.
Deposit date:2001-03-13
Release date:2002-07-10
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
1I98
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BU of 1i98 by Molmil
NMR ENSEMBLE OF ION-SELECTIVE LIGAND D18 FOR PLATELET INTEGRIN ALPHAIIB-BETA3
Descriptor: ION-SELECTIVE LIGAND D18
Authors:Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N.
Deposit date:2001-03-18
Release date:2002-07-10
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
2YN6
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BU of 2yn6 by Molmil
Pentameric Ligand-Gated Ion Channel ELIC in Complex with Barium
Descriptor: BARIUM ION, PENTAMERIC LIGAND-GATED ION CHANNEL ELIC
Authors:Zimmermann, I, Marabelli, A, Bertozzi, C, Sivilotti, L.G, Dutzler, R.
Deposit date:2012-10-12
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel Elic by Divalent Cations.
Plos Biol., 10, 2012
2YOE
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BU of 2yoe by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam
Descriptor: CYS-LOOP LIGAND-GATED ION CHANNEL, Flurazepam, GAMMA-AMINO-BUTANOIC ACID
Authors:Spurny, R, Brams, M, Nury, H, Legrand, P, Ulens, C.
Deposit date:2012-10-23
Release date:2012-10-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
1I6Y
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BU of 1i6y by Molmil
NMR ENSEMBLE OF ION-SELECTIVE LIGAND A1 FOR PLATELET INTEGRIN ALPHAIIB-BETA3
Descriptor: ION-SELECTIVE LIGAND A1
Authors:Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N.
Deposit date:2001-03-06
Release date:2002-07-10
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
4OTG
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BU of 4otg by Molmil
Crystal Structure of PRK1 Catalytic Domain in Complex with Lestaurtinib
Descriptor: Lestaurtinib, Serine/threonine-protein kinase N1
Authors:Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B.
Deposit date:2014-02-13
Release date:2014-08-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes.
Plos One, 9, 2014
4OTH
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BU of 4oth by Molmil
Crystal Structure of PRK1 Catalytic Domain in Complex with Ro-31-8220
Descriptor: BISINDOLYLMALEIMIDE IX, Serine/threonine-protein kinase N1
Authors:Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B.
Deposit date:2014-02-13
Release date:2014-08-27
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes.
Plos One, 9, 2014
4OTD
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BU of 4otd by Molmil
Crystal Structure of PRK1 Catalytic Domain
Descriptor: Serine/threonine-protein kinase N1
Authors:Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B.
Deposit date:2014-02-13
Release date:2014-08-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes.
Plos One, 9, 2014
1I93
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BU of 1i93 by Molmil
NMR ENSEMBLE OF ION-SELECTIVE LIGAND D16 FOR PLATELET INTEGRIN ALPHAIIB-BETA3
Descriptor: ION-SELECTIVE LIGAND D16
Authors:Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N.
Deposit date:2001-03-17
Release date:2002-07-10
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
1VQZ
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BU of 1vqz by Molmil
Crystal structure of a putative lipoate-protein ligase a (sp_1160) from streptococcus pneumoniae tigr4 at 1.99 A resolution
Descriptor: 1,2-ETHANEDIOL, UNKNOWN LIGAND, lipoate-protein ligase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-01-21
Release date:2005-02-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of putative Lipoate-protein ligase (np_345629.1) from Streptococcus pneumoniae tigr4 at 1.99 A resolution
To be published
1VS0
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BU of 1vs0 by Molmil
Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A
Descriptor: CHLORIDE ION, MAGNESIUM ION, Putative DNA ligase-like protein Rv0938/MT0965, ...
Authors:Akey, D, Martins, A, Aniukwu, J, Glickman, M.S, Shuman, S, Berger, J.M, TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-01-27
Release date:2006-02-28
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D.
J.Biol.Chem., 281, 2006
4DZH
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BU of 4dzh by Molmil
Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn
Descriptor: AMIDOHYDROLASE, GLYCEROL, MAGNESIUM ION, ...
Authors:Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Chamala, S, Kar, A, Lafleur, J, Villigas, G, Evans, B, Hammonds, J, Gizzi, A, Zencheck, W.D, Hillerich, B, Love, J, Seidel, R.D, Bonanno, J.B, Raushel, F.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-03-01
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn
to be published
5DKA
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BU of 5dka by Molmil
A C2HC zinc finger is essential for the activity of the RING ubiquitin ligase RNF125
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF125, MAGNESIUM ION, ...
Authors:Boer, D.R, Coll, M, Bijlmakers, M.J.
Deposit date:2015-09-03
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125.
Sci Rep, 6, 2016
7EV3
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BU of 7ev3 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP
Descriptor: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-05-20
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EV2
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BU of 7ev2 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP
Descriptor: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-05-20
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
6AGY
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BU of 6agy by Molmil
Aspergillus fumigatus Af293 NDK
Descriptor: Nucleoside diphosphate kinase
Authors:Hu, Y, Han, L.
Deposit date:2018-08-15
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of crystal structure and key residues of Aspergillus fumigatus nucleoside diphosphate kinase.
Biochem. Biophys. Res. Commun., 511, 2019
2C8M
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BU of 2c8m by Molmil
Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum with bound lipoic acid
Descriptor: LIPOATE-PROTEIN LIGASE A, LIPOIC ACID
Authors:McManus, E, Perham, R.N, Luisi, B.F.
Deposit date:2005-12-06
Release date:2005-12-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure of a Putative Lipoate Protein Ligase from Thermoplasma Acidophilum and the Mechanism of Target Selection for Post-Translational Modification.
J.Mol.Biol., 356, 2006
7P47
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BU of 7p47 by Molmil
Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic
Descriptor: E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ...
Authors:Lascorz, J, Varejao, N, Reverter, D.
Deposit date:2021-07-09
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.314 Å)
Cite:Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.
Nat Commun, 12, 2021
6FGA
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BU of 6fga by Molmil
Crystal structure of TRIM21 E3 ligase, RING domain in complex with its cognate E2 conjugating enzyme UBE2E1
Descriptor: E3 ubiquitin-protein ligase TRIM21, GLYCEROL, Ubiquitin-conjugating enzyme E2 E1, ...
Authors:Anandapadamanaban, M, Moche, M, Sunnerhagen, M.
Deposit date:2018-01-10
Release date:2019-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:E3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2.
J.Biol.Chem., 294, 2019
1IK9
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BU of 1ik9 by Molmil
CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX
Descriptor: DNA LIGASE IV, DNA REPAIR PROTEIN XRCC4
Authors:Sibanda, B.L, Critchlow, S.E, Begun, J, Pei, X.Y, Jackson, S.P, Blundell, T.L, Pellegrini, L.
Deposit date:2001-05-03
Release date:2001-11-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an Xrcc4-DNA ligase IV complex.
Nat.Struct.Biol., 8, 2001
2CMN
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BU of 2cmn by Molmil
A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, SENSOR PROTEIN FIXL
Authors:Gilles-Gonzalez, M.-A, Caceres, A.I, Silva Sousa, E.H, Tomchick, D.R, Brautigam, C.A, Gonzalez, C, Machius, M.
Deposit date:2006-05-11
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium Japonicum Fixl Oxygen Sensor
J.Mol.Biol., 360, 2006
2ARU
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BU of 2aru by Molmil
Crystal structure of lipoate-protein ligase A bound with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Lipoate-protein ligase A, MAGNESIUM ION
Authors:Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W.
Deposit date:2005-08-22
Release date:2005-10-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
J.Biol.Chem., 280, 2005
2CGH
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BU of 2cgh by Molmil
crystal structure of biotin ligase from Mycobacterium tuberculosis
Descriptor: BIOTIN LIGASE
Authors:Ma, Q, Wilmanns, M.
Deposit date:2006-03-06
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active Site Conformational Changes Upon Reaction Intermediate Biotinyl-5'-AMP Binding in Biotin Protein Ligase from Mycobacterium Tuberculosis.
Protein Sci., 23, 2014

238582

数据于2025-07-09公开中

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