PDB: 17019 resultsInfo pagesStatus searchChemie searchBIRD

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3N3L	Human FPPS complex with FBS_03 Descriptor: (6-methoxy-1-benzofuran-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION Authors: Rondeau, J.-M. Deposit date: 2010-05-20 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N45	Human FPPS complex with FBS_04 and zoledronic acid/MG2+ Descriptor: (2S)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, ... Authors: Rondeau, J.-M. Deposit date: 2010-05-21 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N5H	Human fpps complex with NOV_304 Descriptor: 3-(carboxymethyl)-4,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION Authors: Rondeau, J.-M. Deposit date: 2010-05-25 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N6K	Human FPPS complex with NOV_823 Descriptor: 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION Authors: Rondeau, J.-M. Deposit date: 2010-05-26 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N5J	Human fpps complex with NOV_311 Descriptor: 3-(carboxymethyl)-5,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION Authors: Rondeau, J.-M. Deposit date: 2010-05-25 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N1W	Human FPPS COMPLEX WITH FBS_02 Descriptor: (5-chloro-1-benzothiophen-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION Authors: Rondeau, J.-M. Deposit date: 2010-05-17 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3OMZ	Crystal structure of MICA-specific human gamma delta T cell receptor Descriptor: human Vdelta1 gamma delta T cell receptor delta1A/B-3 Authors: Xu, B, Holmes, M.A, Strong, R.K. Deposit date: 2010-08-27 Release date: 2011-01-26 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Crystal structure of a {gamma}{delta} T-cell receptor specific for the human MHC class I homolog MICA. Proc.Natl.Acad.Sci.USA, 108, 2011
5OBA	Structure of a modified mouse H-chain ferritin with a lanthanide binding motif Descriptor: FE (III) ION, Ferritin heavy chain Authors: Baiocco, P, Trabuco, M.C. Deposit date: 2017-06-26 Release date: 2018-07-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Engineered ferritin for lanthanide binding. PLoS ONE, 13, 2018
5O3I	Human Brd2(BD2) mutant in complex with AL-tBu Descriptor: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... Authors: Chan, K.-H, Runcie, A.C, Ciulli, A. Deposit date: 2017-05-23 Release date: 2018-02-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
4QPW	BiXyn10A CBM1 with Xylohexaose Bound Descriptor: beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, glycosyl hydrolase family 10 Authors: Chekan, J.R, Nair, S.K. Deposit date: 2014-06-25 Release date: 2014-08-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.14 Å) Cite: Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes. Proc.Natl.Acad.Sci.USA, 111, 2014
5DEF	Crystal structure of B*27:04 complex bound to the pVIPR peptide Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... Authors: Loll, B, Fabian, H, Huser, H, Hee, C.S, Uchanska-Ziegler, B, Ziegler, A. Deposit date: 2015-08-25 Release date: 2015-11-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis. Arthritis Rheumatol, 68, 2016
4LNL	Structure of Escherichia coli Threonine Aldolase in Complex with Allo-Thr Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Low-specificity L-threonine aldolase, ... Authors: Safo, M.K. Deposit date: 2013-07-11 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
5DEG	Crystal structure of B*27:06 bound to the pVIPR peptide Descriptor: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... Authors: Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A. Deposit date: 2015-08-25 Release date: 2015-11-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis. Arthritis Rheumatol, 68, 2016
4RJY	Crystal structure of E. coli L-Threonine Aldolase in complex with a non-covalently uncleaved bound L-serine substrate Descriptor: Low specificity L-threonine aldolase, SERINE, SODIUM ION Authors: Safo, M.K, Chowdhury, N, Gandhi, A.K. Deposit date: 2014-10-11 Release date: 2014-10-29 Last modified: 2015-02-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Molecular basis of E. colil-threonine aldolase catalytic inactivation at low pH. Biochim.Biophys.Acta, 1854, 2015
5OBB	Structure of a modified mouse H chain ferritin with a lanthanide binding motif in complex with Terbium Descriptor: Ferritin heavy chain, TERBIUM(III) ION Authors: Baiocco, P, Trabuco, M.C. Deposit date: 2017-06-26 Release date: 2018-07-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Engineered ferritin for lanthanide binding. PLoS ONE, 13, 2018
4APN	Structure of TR from Leishmania infantum in complex with a diarylpirrole-based inhibitor Descriptor: 4-[[1-(4-ethylphenyl)-2-methyl-5-(4-methylsulfanylphenyl)pyrrol-3-yl]methyl]thiomorpholine, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Baiocco, P, Ilari, A, Colotti, G, Biava, M. Deposit date: 2012-04-04 Release date: 2013-04-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
4GSA	CRYSTAL STRUCTURE OF GLUTAMATE-1-SEMIALDEHYDE AMINOMUTASE (AMINOTRANSFERASE) REDUCED WITH CYANOBOROHYDRATE Descriptor: GLUTAMATE SEMIALDEHYDE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Hennig, M, Jansonius, J.N. Deposit date: 1997-02-26 Release date: 1998-03-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity. Proc.Natl.Acad.Sci.USA, 94, 1997
2QVW	Structure of Giardia Dicer refined against twinned data Descriptor: GLP_546_48378_50642, MANGANESE (II) ION Authors: Doudna, J.A, MacRae, I.J. Deposit date: 2007-08-09 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer Acta Crystallogr.,Sect.D, 63, 2007
4G7Y	Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.8 A) Descriptor: CHLORIDE ION, Fragment antibody heavy chain, Fragment antibody light chain, ... Authors: Li, Q. Deposit date: 2012-07-20 Release date: 2014-02-05 Last modified: 2019-07-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nat. Struct. Mol. Biol., 21, 2014
4FIN	Crystal Structure of EttA (formerly YjjK) - an E. coli ABC-type ATPase Descriptor: CITRIC ACID, EttA (YjjK) ABCF family protein, GLYCEROL, ... Authors: Smith, P, Yuan, Y, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2012-06-09 Release date: 2013-07-03 Last modified: 2014-03-05 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The ABC-F protein EttA gates ribosome entry into the translation elongation cycle. Nat.Struct.Mol.Biol., 21, 2014
3ST2	Dreiklang - equilibrium state Descriptor: Dreiklang, PHOSPHATE ION Authors: Brakemann, T, Weber, G, Andresen, M, Stiel, A.C, Jakobs, S, Wahl, M.C. Deposit date: 2011-07-08 Release date: 2011-09-14 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat.Biotechnol., 29, 2011
3ST4	Dreiklang - on state Descriptor: Dreiklang, PHOSPHATE ION Authors: Brakemann, T, Weber, G, Andresen, M, Stiel, A.C, Jakobs, S, Wahl, M.C. Deposit date: 2011-07-08 Release date: 2011-09-14 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat.Biotechnol., 29, 2011
3ST3	Dreiklang - off state Descriptor: Dreiklang, PHOSPHATE ION Authors: Brakemann, T, Weber, G, Andresen, M, Stiel, A.C, Jakobs, S, Wahl, M.C. Deposit date: 2011-07-08 Release date: 2011-09-14 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.702 Å) Cite: A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat.Biotechnol., 29, 2011
2KHC	Bruno RRM3+ Descriptor: Testis-specific RNP-type RNA binding protein Authors: Lyon, A.M, Reveal, B.S, Macdonald, P.M, Hoffman, D.W. Deposit date: 2009-04-01 Release date: 2009-12-22 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Bruno protein contains an expanded RNA recognition motif. Biochemistry, 48, 2009
6WJH	Crystal structure of MAGE-A11 bound to the PCF11 degron Descriptor: Fusion protein of PCF11 and MAGE-A11 Authors: Miller, D.J, Huang, X. Deposit date: 2020-04-13 Release date: 2020-10-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases. Nat Commun, 11, 2020

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