PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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7KUM	LNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G Descriptor: 5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(LCG)-3', DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Fang, Z, Giurgiu, C, Szostak, J.W. Deposit date: 2020-11-25 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.714 Å) Cite: Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
7KUP	2'-OMe modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G Descriptor: 5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(OMG))-3', DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Fang, Z, Giurgiu, C, Szostak, J.W. Deposit date: 2020-11-25 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
6QIS	Crystal structure of CAG repeats with synthetic CMBL3a compound (model II) Descriptor: CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), SULFATE ION Authors: Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. Deposit date: 2019-01-21 Release date: 2019-09-25 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
6QIV	Crystal structure of seleno-derivative CAG repeats with synthetic CMBL4 compound Descriptor: CMBL4, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') Authors: Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. Deposit date: 2019-01-21 Release date: 2019-09-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
1J26	Solution structure of a putative peptidyl-tRNA hydrolase domain in a mouse hypothetical protein Descriptor: immature colon carcinoma transcript 1 Authors: Nameki, N, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2002-12-25 Release date: 2004-06-01 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality J.Mol.Biol., 2010
2PXH	Crystal structure of a bipyridylalanyl-tRNA synthetase Descriptor: 3-(2,2'-BIPYRIDIN-5-YL)-L-ALANINE, Tyrosyl-tRNA synthetase Authors: Liu, W, Xie, J, Schultz, P.G. Deposit date: 2007-05-14 Release date: 2008-02-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.97 Å) Cite: A genetically encoded bidentate, metal-binding amino acid. Angew.Chem.Int.Ed.Engl., 46, 2007
5G4T	The structure of a quasi-cyclic six k-turn duplex RNA species Descriptor: HMKT-7 Authors: Huang, L, Lilley, D.M.J. Deposit date: 2016-05-17 Release date: 2016-09-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.751 Å) Cite: A Quasi-Cyclic RNA Nano-Scale Molecular Object Constructed Using Kink Turns. Nanoscale, 8, 2016
5QY3	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry B03a Descriptor: 2-[(1~{S})-1-azanylpropyl]phenol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.58 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY2	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A12b Descriptor: 3-(propan-2-yl)-1,2,4-oxadiazol-5(4H)-one, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.36 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY4	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry B08a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.57 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY6	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C05a Descriptor: 2-methoxy-4-[[(4~{S},5~{S})-2,4,5-tris(2-methoxypyridin-4-yl)imidazolidin-1-yl]methyl]pyridine, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY5	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C02a Descriptor: 2,4,5-tris(fluoranyl)-3-methoxy-benzoic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY1	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A07a Descriptor: (2-aminopyridin-3-yl)methanol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.72 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY7	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C08a Descriptor: (1S,3S)-2-methyl-2,3-dihydro-1H-isoindole-1,3-diol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYA	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D02a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY9	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C11b Descriptor: A1 cistron-splicing factor AAR2, N-ethyl-N-(thiophene-2-carbonyl)-beta-alanine, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QY8	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C10a Descriptor: 1,3-benzodioxole-5-carbothioamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.59 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYC	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D07a Descriptor: 2-fluoranyl-~{N}-(furan-2-ylmethyl)benzenesulfonamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYD	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E05a Descriptor: 2-(2-methylphenyl)acetamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYE	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E12a Descriptor: (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYF	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry F02a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.49 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYG	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry F08a Descriptor: 4-[(methylamino)methyl]phenol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYL	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 01 Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYM	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 02 Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.47 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5QYK	PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry H12a Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-02-12 Release date: 2020-06-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020

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