3K72
 
 | | Structure of integrin alphaX beta2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | | Deposit date: | 2009-10-11 | | Release date: | 2010-01-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
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3K6S
 | | Structure of integrin alphaXbeta2 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | | Deposit date: | 2009-10-09 | | Release date: | 2010-01-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
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3SHM
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3S7G
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1OR3
 | | APOLIPOPROTEIN E3 (APOE3), TRIGONAL TRUNCATION MUTANT 165 | | Descriptor: | PROTEIN (APOLIPOPROTEIN E) | | Authors: | Rupp, B, Segelke, B.W. | | Deposit date: | 1998-12-01 | | Release date: | 2000-05-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
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3GI8
 | | Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment | | Descriptor: | 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609 | | Authors: | Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2009-03-05 | | Release date: | 2009-08-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
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1N0S
 | | ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN | | Descriptor: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Bilin-binding protein, SULFATE ION | | Authors: | Korndoerfer, I.P, Skerra, A. | | Deposit date: | 2002-10-15 | | Release date: | 2003-08-05 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region.
Proteins, 53, 2003
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3KIC
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1LZ6
 | | STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME | | Descriptor: | CHLORIDE ION, HUMAN LYSOZYME | | Authors: | Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M. | | Deposit date: | 1993-02-03 | | Release date: | 1993-10-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme.
J.Biol.Chem., 268, 1993
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7XRP
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C5G2 nanobody, Spike protein S1 | | Authors: | Liu, L, Sun, H, Jiang, Y, Liu, X, Zhao, D, Zheng, Q, Li, S, Xia, N. | | Deposit date: | 2022-05-11 | | Release date: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode.
J Nanobiotechnology, 20, 2022
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1OW0
 | | Crystal structure of human FcaRI bound to IgA1-Fc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig alpha-1 chain C region, Immunoglobulin alpha Fc receptor, ... | | Authors: | Herr, A.B, Ballister, E.R, Bjorkman, P.J. | | Deposit date: | 2003-03-27 | | Release date: | 2003-05-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc
Nature, 423, 2003
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3L9J
 | | Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex | | Descriptor: | MAGNESIUM ION, TNFalpha, Tumor necrosis factor, ... | | Authors: | Byla, P, Andersen, M.H, Thogersen, H.C, Gad, H.H, Hartmann, R. | | Deposit date: | 2010-01-05 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex
J.Biol.Chem., 285, 2010
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3LE2
 | | Structure of Arabidopsis AtSerpin1. Native Stressed Conformation | | Descriptor: | ACETATE ION, GLYCEROL, SULFATE ION, ... | | Authors: | Harrop, S.J, Joss, T.V, Cumi, P.M.G, Roberts, T.H. | | Deposit date: | 2010-01-14 | | Release date: | 2010-02-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21).
J.Biol.Chem., 285, 2010
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3RI0
 | | Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins | | Descriptor: | BB_2cx5_001, GLYCEROL, SULFATE ION | | Authors: | Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R. | | Deposit date: | 2011-04-12 | | Release date: | 2011-11-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
J.Mol.Biol., 415, 2012
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1O0V
 | | The crystal structure of IgE Fc reveals an asymmetrically bent conformation | | Descriptor: | GLYCEROL, Immunoglobulin heavy chain epsilon-1, SULFATE ION, ... | | Authors: | Wan, T, Beavil, R.L, Fabiane, S.M, Beavil, A.J, Sohi, M.K, Keown, M, Young, R.J, Henry, A.J, Owens, R.J, Gould, H.J, Sutton, B.J. | | Deposit date: | 2002-09-06 | | Release date: | 2002-09-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The crystal structure of IgE Fc reveals an asymmetrically bent conformation
NAT.IMMUNOL., 3, 2002
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3O6L
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1P4P
 | | Outer Surface Protein B of B. burgdorferi: crystal structure of the C-terminal fragment | | Descriptor: | Outer surface protein B | | Authors: | Becker, M, Bunikis, J, Lade, B.D, Dunn, J.J, Barbour, A.G, Lawson, C.L. | | Deposit date: | 2003-04-23 | | Release date: | 2004-05-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Investigation of Borrelia burgdorferi OspB, a BactericidalFab Target.
J.Biol.Chem., 280, 2005
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3OED
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3O6M
 | | Anti-Tat HIV 11H6H1 Fab' complexed with a 9-mer Tat peptide | | Descriptor: | 11H6H1 Fab' heavy chain, 11H6H1 Fab' light chain, Protein Tat 9-mer peptide | | Authors: | Serriere, J, Gouet, P, Guillon, C. | | Deposit date: | 2010-07-29 | | Release date: | 2010-11-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Fab'-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography.
J.Mol.Biol., 405, 2011
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3SOQ
 | | The structure of the first YWTD beta propeller domain of LRP6 in complex with a DKK1 peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dickkopf-related protein 1, ... | | Authors: | Wang, W, Bourhis, E, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G. | | Deposit date: | 2011-06-30 | | Release date: | 2011-09-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
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5WXH
 | | Crystal structure of TAF3 PHD finger bound to H3K4me3 | | Descriptor: | Histone H3K4me3, Transcription initiation factor TFIID subunit 3, ZINC ION | | Authors: | Zhao, S, Huang, J, Li, H. | | Deposit date: | 2017-01-07 | | Release date: | 2017-08-16 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (1.297 Å) | | Cite: | Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WXG
 | | Structure of TAF PHD finger domain binds to H3(1-15)K4ac | | Descriptor: | Histone H3K4ac, MAGNESIUM ION, Transcription initiation factor TFIID subunit 3, ... | | Authors: | Zhao, S, Li, H. | | Deposit date: | 2017-01-07 | | Release date: | 2017-08-16 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (1.703 Å) | | Cite: | Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1PAK
 | | NMR SOLUTION STRUCTURE AND FLEXIBILITY OF A PEPTIDE ANTIGEN REPRESENTING THE RECEPTOR BINDING DOMAIN OF PSEUDOMONAS AERUGINOSA | | Descriptor: | FIMBRIAL PROTEIN PRECURSOR, HYDROXIDE ION | | Authors: | Mcinnes, C, Sonnichsen, F.D, Kay, C.M, Hodges, R.S, Sykes, B.D. | | Deposit date: | 1993-08-25 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure and flexibility of a peptide antigen representing the receptor binding domain of Pseudomonas aeruginosa.
Biochemistry, 32, 1993
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4WI8
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation Y436A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose, ... | | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | Deposit date: | 2014-09-25 | | Release date: | 2015-09-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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4WI2
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type) | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | Deposit date: | 2014-09-25 | | Release date: | 2015-09-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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