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8BLA
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BU of 8bla by Molmil
Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Lopez-Sanchez, U, Nury, H.
Deposit date:2022-11-09
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 2024
8BL8
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BU of 8bl8 by Molmil
Human serotonin 5-HT3A receptor (apo, active/distorted conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A
Authors:Lopez-Sanchez, U, Nury, H.
Deposit date:2022-11-09
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 2024
8BLB
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BU of 8blb by Molmil
Human serotonin 5-HT3A receptor in complex with vortioxetine (nanodiscs, ECD, active/distorted conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Lopez-Sanchez, U, Nury, H.
Deposit date:2022-11-09
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 2024
4II7
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BU of 4ii7 by Molmil
Archaellum Assembly ATPase FlaI
Descriptor: FlaI ATPase
Authors:Reindl, S, Williams, G.J, Tainer, J.A.
Deposit date:2012-12-20
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Insights into FlaI Functions in Archaeal Motor Assembly and Motility from Structures, Conformations, and Genetics.
Mol.Cell, 49, 2013
4IHQ
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BU of 4ihq by Molmil
Archaellum Assembly ATPase FlaI bound to ADP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FlaI ATPase, ...
Authors:Reindl, S, Williams, G.J, Tainer, J.A.
Deposit date:2012-12-19
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into FlaI Functions in Archaeal Motor Assembly and Motility from Structures, Conformations, and Genetics.
Mol.Cell, 49, 2013
4LAX
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BU of 4lax by Molmil
Crystal Structure Analysis of FKBP52, Complex with FK506
Descriptor: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
Deposit date:2013-06-20
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LAV
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BU of 4lav by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form II
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP4, SULFATE ION
Authors:Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
Deposit date:2013-06-20
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LAY
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BU of 4lay by Molmil
Crystal Structure Analysis of FKBP52, Complex with I63
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
Authors:Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
Deposit date:2013-06-20
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LAW
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BU of 4law by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form III
Descriptor: DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP4
Authors:Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
Deposit date:2013-06-20
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
3U50
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BU of 3u50 by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C
Descriptor: Telomerase-associated protein 82, ZINC ION
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-10
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
1WXX
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BU of 1wxx by Molmil
Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
Descriptor: PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-02
Release date:2005-08-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
3U58
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BU of 3u58 by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB
Descriptor: DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-11
Release date:2011-12-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.613 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
7L7V
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BU of 7l7v by Molmil
Crystal structure of Arabidopsis NRG1.1 CC-R domain K94E/K96E/R99E/K100E/R103E/K106E/K110E mutant
Descriptor: Probable disease resistance protein At5g66900
Authors:Walton, W.G, Wan, L, Lietzan, A.D, Redinbo, M.R, Dangl, J.L.
Deposit date:2020-12-30
Release date:2021-06-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Plant "helper" immune receptors are Ca 2+ -permeable nonselective cation channels.
Science, 373, 2021
7L7W
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BU of 7l7w by Molmil
Crystal structure of Arabidopsis NRG1.1 CC-R domain K94E/K96E mutant
Descriptor: NICKEL (II) ION, Probable disease resistance protein At5g66900
Authors:Walton, W.G, Wan, L, Lietzan, A.D, Redinbo, M.R, Dangl, J.L.
Deposit date:2020-12-30
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Plant "helper" immune receptors are Ca 2+ -permeable nonselective cation channels.
Science, 373, 2021
1WXW
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BU of 1wxw by Molmil
Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
Descriptor: HEXANE-1,6-DIOL, hypothetical protein TTHA1280
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-02
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
3SNY
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BU of 3sny by Molmil
Crystal structure of a mutant T82R of a betagamma-crystallin domain from Clostridium beijerinckii
Descriptor: CALCIUM ION, Clostrillin, SULFATE ION
Authors:Srivastava, S.S, Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3SO1
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BU of 3so1 by Molmil
Crystal structure of a double mutant T41S T82S of a betagamma-crystallin domain from Clostridium beijerinckii
Descriptor: CALCIUM ION, Clostrillin, SULFATE ION
Authors:Srivastava, S.S, Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3H6W
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BU of 3h6w by Molmil
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution
Descriptor: (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ...
Authors:Hald, H, Gajhede, M, Kastrup, J.S.
Deposit date:2009-04-24
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
3SO0
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BU of 3so0 by Molmil
Crystal structure of a mutant T41S of a betagamma-crystallin domain from Clostridium beijerinckii
Descriptor: CALCIUM ION, Clostrillin
Authors:Srivastava, S.S, Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3U4V
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BU of 3u4v by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-A
Descriptor: Telomerase-associated protein 82
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-10
Release date:2011-12-28
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U4Z
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BU of 3u4z by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-B
Descriptor: Telomerase-associated protein 82
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-10
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
7ME1
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BU of 7me1 by Molmil
YfeA oligomer crystal 1, form 1
Descriptor: FE (III) ION, MANGANESE (II) ION, Periplasmic chelated iron-binding protein YfeA, ...
Authors:Radka, C.D, Aller, S.G.
Deposit date:2021-04-06
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site.
Acta Crystallogr.,Sect.F, 77, 2021
3H6T
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BU of 3h6t by Molmil
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and cyclothiazide at 2.25 A resolution
Descriptor: ACETATE ION, CACODYLATE ION, CYCLOTHIAZIDE, ...
Authors:Hald, H, Gajhede, M, Kastrup, J.S.
Deposit date:2009-04-24
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
3H6V
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BU of 3h6v by Molmil
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution
Descriptor: (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ...
Authors:Hald, H, Gajhede, M, Kastrup, J.S.
Deposit date:2009-04-24
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
1YQT
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BU of 1yqt by Molmil
RNase-L Inhibitor
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNase l inhibitor
Authors:Karcher, A, Buttner, K, Martens, B, Jansen, R.P, Hopfner, K.P.
Deposit date:2005-02-02
Release date:2005-04-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of RLI, an essential twin cassette ABC ATPase involved in ribosome biogenesis and HIV capsid assembly.
Structure, 13, 2005

223532

数据于2024-08-07公开中

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