PDB: 223790 resultsInfo pagesStatus searchChemie searchBIRD

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5L8G	Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant H65A Descriptor: CALCIUM ION, Uncharacterized protein Authors: He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. Deposit date: 2016-06-07 Release date: 2016-08-31 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.974 Å) Cite: Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife, 5, 2016
6QEF	CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR (S)-3-Hydroxy-2-oxo-1-phenyl-pyrrolidine-3-carboxylic acid 3-chloro-5-fluoro-benzylamide Descriptor: (3~{S})-~{N}-[(3-chloranyl-5-fluoranyl-phenyl)methyl]-3-oxidanyl-2-oxidanylidene-1-phenyl-pyrrolidine-3-carboxamide, 1,2-ETHANEDIOL, GLYCEROL, ... Authors: Musil, D, Heinrich, T, Lehmann, M. Deposit date: 2019-01-07 Release date: 2019-05-01 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase-2 (MetAP-2) Inhibitors. J.Med.Chem., 62, 2019
6QEQ	PcfF from Enterococcus faecalis pCF10 Descriptor: PcfF Authors: Rehman, S, Berntsson, R.P.A. Deposit date: 2019-01-08 Release date: 2019-05-01 Last modified: 2019-10-02 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Enterococcal PcfF Is a Ribbon-Helix-Helix Protein That Recruits the Relaxase PcfG Through Binding and Bending of the oriT Sequence. Front Microbiol, 10, 2019
5W3E	CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle) Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ... Authors: Liu, Y, Dong, Y, Rossmann, M.G. Deposit date: 2017-06-07 Release date: 2017-07-12 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Antibody-induced uncoating of human rhinovirus B14. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6QHK	PAO-linked dimer of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Phenylarsine oxide, ... Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-01-16 Release date: 2019-07-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure, 27, 2019
6QFL	Structure of the mitogen activated kinase kinase 7 active conformation Descriptor: Dual specificity mitogen-activated protein kinase kinase 7 Authors: Wolle, P, Mueller, M.P, Rauh, D. Deposit date: 2019-01-10 Release date: 2019-05-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
5W4I	X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Rigaku data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV. Descriptor: A-beta 17_36: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL, CHLORIDE ION, IODIDE ION Authors: Kreutzer, A.G, McKnelly, K.J, Nowick, J.S. Deposit date: 2017-06-11 Release date: 2017-11-22 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.026 Å) Cite: A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56, 2017
8XQ4	Structure of the sea urchin spSLC9C1 in state-2 w/o cAMP protomer Descriptor: Sperm-specific sodium proton exchanger Authors: Qu, H, Zheng, X. Deposit date: 2024-01-04 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Structures of a sperm-specific sodium-hydrogen exchanger. Cell Insight, 3, 2024
8SUR	TMEM16F bound with Niclosamide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide, ... Authors: Feng, S, Cheng, Y. Deposit date: 2023-05-13 Release date: 2023-09-06 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14, 2023
4UYQ	High resolution structure of the third cohesin ScaC in complex with the ScaB dockerin with a mutation in the C-terminal helix (IN to SI) from Acetivibrio cellulolyticus displaying a type I interaction. Descriptor: CALCIUM ION, Cellulosomal scaffoldin adaptor protein B, Cellulosomal scaffoldin anchoring protein C Authors: Cameron, K, Fontes, C.M.G.A, Najmudin, S. Deposit date: 2014-09-02 Release date: 2015-04-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Cell-surface Attachment of Bacterial Multienzyme Complexes Involves Highly Dynamic Protein-Protein Anchors. J. Biol. Chem., 290, 2015
8XQ8	Structure of the sea urchin spSLC9C1 in state-1 w/ cAMP protomer Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger Authors: Qu, H, Zheng, X. Deposit date: 2024-01-04 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structures of a sperm-specific sodium-hydrogen exchanger. Cell Insight, 3, 2024
5KR5	Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries Descriptor: 4-aminobutyrate transaminase, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Wilding, M, Newman, J, Peat, T.S, Scott, C. Deposit date: 2016-07-07 Release date: 2017-07-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19, 2017
6QIZ	CI-2, conformation 2 Descriptor: Subtilisin-chymotrypsin inhibitor-2A Authors: Romero, A, Ruiz, F.M. Deposit date: 2019-01-21 Release date: 2019-12-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Engineering protein assemblies with allosteric control via monomer fold-switching. Nat Commun, 10, 2019
6QJ7	Difluorophenyl diacylhydrazides: Potent inhibitors of Serum- and Glucocorticoid-inducible Kinase 1 (SGK1) Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ~{N}'-[(2~{S})-2-[3,5-bis(fluoranyl)phenyl]-2-oxidanyl-ethanoyl]-2-ethyl-3-methyl-4-oxidanyl-benzohydrazide Authors: Graedler, U. Deposit date: 2019-01-23 Release date: 2020-02-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Difluorophenyl diacylhydrazides: Potent inhibitors of Serum- and Glucocorticoid-inducible Kinase 1 (SGK1) To Be Published
5W4J	X-ray crystallographic structure of a beta-hairpin peptide mimic. (ORN)KLV(MEA)FAE(ORN)AIIGLMV. Descriptor: A-beta 17_36 peptide: ORN-LYS-VAL-PHE-MEA-ALA-ALA-ASP-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL Authors: Kreutzer, A.G, Nowick, J.S. Deposit date: 2017-06-11 Release date: 2017-11-22 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.08 Å) Cite: A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56, 2017
4UFI	Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF Descriptor: (3R,4S,5R)-3-(hydroxymethyl)-1,2-diazinane-4,5-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. Deposit date: 2015-03-17 Release date: 2015-03-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
4V0H	Human metallo beta lactamase domain containing protein 1 (hMBLAC1) Descriptor: FE (III) ION, GLYCEROL, METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 1 Authors: Pettinati, I, McDonough, M.A, Brem, J, Schofield, C.J. Deposit date: 2014-09-16 Release date: 2016-01-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease. Elife, 7, 2018
5W65	RNA polymerase I Initial Transcribing Complex State 2 Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Han, Y, He, Y. Deposit date: 2017-06-16 Release date: 2017-08-02 Last modified: 2019-11-27 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
5W64	RNA Polymerase I Initial Transcribing Complex State 1 Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Han, Y, He, Y. Deposit date: 2017-06-16 Release date: 2017-07-26 Last modified: 2019-11-27 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
6QJ1	Crystal structure of the C. thermophilum condensin Smc2 ATPase head (crystal from I) Descriptor: Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein Authors: Hassler, M, Haering, C.H. Deposit date: 2019-01-22 Release date: 2019-07-03 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Structural Basis of an Asymmetric Condensin ATPase Cycle. Mol.Cell, 74, 2019
6QJU	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with 3-bromo-1H-indazol-5-amine Descriptor: 1,2-ETHANEDIOL, 3-bromanyl-2~{H}-indazol-5-amine, Bromodomain-containing protein 3, ... Authors: Braun, M.B, Stehle, T, Heidrich, J. Deposit date: 2019-01-25 Release date: 2020-02-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.202 Å) Cite: Br-O-modomain (BRD3) halogen binding to a small molecule To Be Published
5KVK	Crystal structure of the Competence-Damaged Protein (CinA) Superfamily Protein KP700603 from Klebsiella pneumoniae 700603 Descriptor: Protein KP700603 Authors: Stogios, P.J, Wawrzak, Z, Evdokimova, E, Di Leo, R, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2016-07-14 Release date: 2016-08-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.66 Å) Cite: To be published To Be Published
8XQA	Structure of the sea urchin spSLC9C1 in state-3 w/ cAMP dimer Descriptor: Sperm-specific sodium proton exchanger Authors: Qu, H, Zheng, X. Deposit date: 2024-01-04 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Structures of a sperm-specific sodium-hydrogen exchanger. Cell Insight, 3, 2024
4W7U	Crystal structure of XacCel5A in the native form Descriptor: CACODYLATE ION, Cellulase Authors: Paiva, J.H, Murakami, M.T. Deposit date: 2014-08-22 Release date: 2015-10-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Crystal structure of XacCel5A in the native form To Be Published
6QK1	R2-like ligand-binding oxidase Y175F mutant with aerobically reconstituted Mn/Fe cofactor Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ... Authors: Griese, J.J, Hogbom, M. Deposit date: 2019-01-28 Release date: 2020-02-19 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.754 Å) Cite: Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein. J.Am.Chem.Soc., 142, 2020

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