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1EH1	RIBOSOME RECYCLING FACTOR FROM THERMUS THERMOPHILUS Descriptor: RIBOSOME RECYCLING FACTOR Authors: Toyoda, T, Tin, O.F, Ito, K, Fujiwara, T, Kumasaka, T, Yamamoto, M, Garber, M.B, Nakamura, Y. Deposit date: 2000-02-18 Release date: 2000-11-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch. RNA, 6, 2000
6E80	Crystal structure of the Corn aptamer in unliganded state Descriptor: ACETATE ION, IRIDIUM HEXAMMINE ION, IRIDIUM ION, ... Authors: Sjekloca, L, Ferre-D'Amare, A.R. Deposit date: 2018-07-27 Release date: 2019-07-31 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.901 Å) Cite: Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence. Cell Chem Biol, 26, 2019
6A6L	Crystal structure of the cold shock domain of YB-1 in complex with m5C RNA Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*CP*AP*UP*(5MC))-3') Authors: Huang, Y. Deposit date: 2018-06-28 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Crystal structure of the cold shock domain of YB-1 in complex with m5C RNA To Be Published
3ADG	Structure of Arabidopsis HYL1 and its molecular implications for miRNA processing Descriptor: F21M12.9 protein Authors: Yuan, Y.A, Chen, H.Y. Deposit date: 2010-01-22 Release date: 2010-05-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing Structure, 18, 2010
3CJ0	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments Descriptor: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
5MGW	Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 Descriptor: PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial Authors: Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. Deposit date: 2016-11-22 Release date: 2017-05-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2. Protein Sci., 26, 2017
5MGU	Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 Descriptor: PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial Authors: Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. Deposit date: 2016-11-22 Release date: 2017-05-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2. Protein Sci., 26, 2017
3CJ3	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3CJ2	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
1I46	The solution structure of the mutant stem loop C 5'GUA3' triloop of brome mosaic virus (+) strand RNA Descriptor: 5'-R(*GP*GP*UP*GP*CP*GP*UP*AP*GP*CP*AP*CP*C)-3' Authors: Kim, C.-H, Tinoco Jr, I. Deposit date: 2001-02-20 Release date: 2001-04-21 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural and thermodynamic studies on mutant RNA motifs that impair the specificity between a viral replicase and its promoter J.Mol.Biol., 307, 2001
1YNJ	Taq RNA polymerase-Sorangicin complex Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. Deposit date: 2005-01-24 Release date: 2005-03-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
5MGH	Crystal structure of pathogenic mutants of human mitochodnrial PheRS Descriptor: PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial Authors: Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. Deposit date: 2016-11-21 Release date: 2017-05-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2. Protein Sci., 26, 2017
1IDV	NMR structure of HCV ires RNA domain IIIC Descriptor: HEPATITIS C IRES RNA DOMAIN IIIC Authors: Kaluarachchi, K, Rijnbrand, R, Lemon, S.M, Gorenstein, D.G. Deposit date: 2001-04-05 Release date: 2001-10-05 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites J.Mol.Biol., 343, 2004
1YNN	Taq RNA polymerase-rifampicin complex Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. Deposit date: 2005-01-24 Release date: 2005-03-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
3CIZ	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments Descriptor: 2-amino-5-bromobenzoic acid, RNA-directed RNA polymerase, ZINC ION Authors: Hendle, j. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
4N4A	Cystal structure of Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Authors: Smietanski, M, Werener, M, Purta, E, Kaminska, K.H, Stepinski, J, Darzynkiewicz, E, Nowotny, M, Bujnicki, J.M. Deposit date: 2013-10-08 Release date: 2014-01-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation. Nat Commun, 5, 2014
1IUH	Crystal structure of TT0787 of thermus thermophilus HB8 Descriptor: 2'-5' RNA Ligase Authors: Kato, M, Sakai, H, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2002-03-05 Release date: 2003-06-17 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the 2'-5' RNA Ligase from Thermus thermophilus HB8 J.MOL.BIOL., 329, 2003
3CJ4	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Antonysamy, s.s. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
2AD9	Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 Authors: Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. Deposit date: 2005-07-20 Release date: 2005-10-04 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structure of PTB bound to RNA: specific binding and implications for splicing regulation Science, 309, 2005
1GX5	Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Bressanelli, S, Rey, F.A. Deposit date: 2002-03-27 Release date: 2002-04-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides J.Virol., 76, 2002
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-07-02 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-07-01 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2ADB	Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 Authors: Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. Deposit date: 2005-07-20 Release date: 2005-10-04 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structure of PTB bound to RNA: specific binding and implications for splicing regulation Science, 309, 2005
2JUK	guanidino neomycin B recognition of an HIV-1 RNA helix Descriptor: (1S,2R,3S,4R,6S)-4,6-bis{[amino(iminio)methyl]amino}-2-{[3-O-(2,6-bis{[amino(iminio)methyl]amino}-2,6-dideoxy-beta-L-glucopyranosyl)-beta-D-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-bis{[amino(iminio)methyl]amino}-2,6-dideoxy-beta-L-glucopyranoside, HIV-1 frameshift site RNA Authors: Staple, D.W, Venditti, V, Niccolai, N, Elson-Schwab, L, Tor, Y, Butcher, S.E. Deposit date: 2007-08-30 Release date: 2007-11-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Guanidinoneomycin B Recognition of an HIV-1 RNA Helix. Chembiochem, 9, 2008
6E84	Crystal structure of the Corn aptamer in complex with TO Descriptor: 1-methyl-4-[(Z)-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]quinolin-1-ium, POTASSIUM ION, RNA (36-MER) Authors: Sjekloca, L, Ferre-D'Amare, A.R. Deposit date: 2018-07-27 Release date: 2019-07-31 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.901 Å) Cite: Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence. Cell Chem Biol, 26, 2019

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