2JUK

guanidino neomycin B recognition of an HIV-1 RNA helix

Summary for 2JUK

Entry DOI	10.2210/pdb2juk/pdb
Descriptor	HIV-1 frameshift site RNA, (1S,2R,3S,4R,6S)-4,6-bis{[amino(iminio)methyl]amino}-2-{[3-O-(2,6-bis{[amino(iminio)methyl]amino}-2,6-dideoxy-beta-L-glucopyranosyl)-beta-D-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-bis{[amino(iminio)methyl]amino}-2,6-dideoxy-beta-L-glucopyranoside (2 entities in total)
Functional Keywords	hiv-1, rna-ligand interactions, guanidinoglycosides, rna
Total number of polymer chains	1
Total formula weight	7944.23
Authors	Staple, D.W.,Venditti, V.,Niccolai, N.,Elson-Schwab, L.,Tor, Y.,Butcher, S.E. (deposition date: 2007-08-30, release date: 2007-11-20, Last modification date: 2022-03-16)
Primary citation	Staple, D.W.,Venditti, V.,Niccolai, N.,Elson-Schwab, L.,Tor, Y.,Butcher, S.E. Guanidinoneomycin B Recognition of an HIV-1 RNA Helix. Chembiochem, 9:93-102, 2008 Cited by PubMed: 18058789 DOI: 10.1002/cbic.200700251 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation