PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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6U03	Crystal Structure of Fungal RNA Kinase Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA ligase Authors: Shuman, S, Goldgur, Y, Banerjee, A. Deposit date: 2019-08-13 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.849 Å) Cite: Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
6U00	Crystal Structure of Fungal RNA Kinase Descriptor: PHOSPHATE ION, tRNA ligase Authors: Shuman, S, Goldgur, Y, Banerjee, A. Deposit date: 2019-08-13 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
6TZO	Crystal Structure of Fungal RNA Kinase Descriptor: 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase Authors: Shuman, S, Goldgur, Y, Banerjee, A. Deposit date: 2019-08-12 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
6TZM	Crystal Structure of Fungal RNA Kinase Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, tRNA ligase Authors: Shuman, S, Goldgur, Y, Banerjee, A. Deposit date: 2019-08-12 Release date: 2019-11-06 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.714 Å) Cite: Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
3WOF	Crystal structure of P23-45 gp39 (6-132) bound to Thermus thermophilus RNA polymerase beta-flap domain Descriptor: DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein Authors: Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S. Deposit date: 2013-12-26 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.298 Å) Cite: Structural basis for promoter specificity switching of RNA polymerase by a phage factor. Genes Dev., 28, 2014
2VOD	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAUUUU Descriptor: 5'-R(*AP*UP*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-15 Release date: 2008-05-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
2JC0	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 Descriptor: (2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC ACID, RNA-DEPENDENT RNA-POLYMERASE Authors: Wonacott, A, Skarzynski, T, Singh, O.M. Deposit date: 2006-12-18 Release date: 2007-02-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. J.Med.Chem., 50, 2007
2JC1	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223 Descriptor: (2S,4S,5R)-1-(4-TERT-BUTYLBENZOYL)-2-ISOBUTYL-5-(1,3-THIAZOL-2-YL)PYRROLIDINE-2,4-DICARBOXYLIC ACID, RNA-DEPENDENT RNA-POLYMERASE Authors: Wonacott, A, Skarzynski, T, Singh, O.M. Deposit date: 2006-12-18 Release date: 2007-02-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. J.Med.Chem., 50, 2007
8D35	Crystal structure of SARS-CoV-2 main protease (Mpro) C145A mutant in complex with peptide from human tRNA methyltransferase TRMT1 Descriptor: 3C-like proteinase nsp5, CHLORIDE ION, GLYCEROL, ... Authors: D'Oliviera, A, Mugridge, J.S. Deposit date: 2022-05-31 Release date: 2023-03-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease. Elife, 2023
2HFZ	Crystal structure of RNA dependent RNA polymerase domain from West Nile virus Descriptor: MAGNESIUM ION, RNA-directed RNA polymerase(NS5), ZINC ION Authors: Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2006-06-26 Release date: 2007-02-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
6U05	Crystal Structure of Fungal RNA Kinase Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Shuman, S, Goldgur, Y, Banerjee, A. Deposit date: 2019-08-13 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.948 Å) Cite: Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
2H1M	Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs Descriptor: 5'-R(*GP*CP*AP*(XUG)P*AP*GP*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', SULFATE ION Authors: Serganov, A.A. Deposit date: 2006-05-16 Release date: 2006-07-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs. J.Am.Chem.Soc., 128, 2006
6CB3	Crystal structure of the L.Lactis YkoY riboswitch bound to cadmium Descriptor: BARIUM ION, CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Bachas, S, Ferre-D'amare, A.R. Deposit date: 2018-02-01 Release date: 2018-06-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.891 Å) Cite: Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators. Cell Chem Biol, 25, 2018
6CC3	Crystal structure of ykoY-mntP riboswitch chimera bound to cadmium Descriptor: CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Bachas, S, Ferre-D'amare, A.R. Deposit date: 2018-02-05 Release date: 2018-06-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.698 Å) Cite: Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators. Cell Chem Biol, 25, 2018
2I91	60kDa Ro autoantigen in complex with a fragment of misfolded RNA Descriptor: 5'-R(*C*GP*GP*UP*AP*GP*GP*CP*UP*UP*UP*UP*CP*AP*A)-3', 5'-R(*GP*CP*CP*UP*AP*CP*CP*C)-3', 60 kDa SS-A/Ro ribonucleoprotein, ... Authors: Reinisch, K.M, Stein, A.J. Deposit date: 2006-09-04 Release date: 2006-10-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural and biochemical basis for misfolded RNA recognition by the Ro autoantigen. Nat.Struct.Mol.Biol., 13, 2006
4KQ0	Crystal structure of double-helical CGG-repetitive RNA 19mer complexed with RSS p19 Descriptor: 5'-R(P*GP*GP*CP*GP*GP*CP*GP*GP*CP*GP*GP*CP*GP*GP*CP*GP*GP*CP*C)-3', RNA silencing suppressor p19, SULFATE ION Authors: Cabo, A, Katorcha, E, Tamjar, J, Popov, A.N, Malinina, L. Deposit date: 2013-05-14 Release date: 2014-05-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insights into CNG-repetitive RNAs associated with human Trinucleotide Repeat Expansion Diseases (TREDs) To be Published
3BX2	Puf4 RNA binding domain bound to HO endonuclease RNA 3' UTR recognition sequence Descriptor: HO endonuclease 3' UTR binding sequence, Protein PUF4, SODIUM ION, ... Authors: Miller, M.T, Higgin, J.J, Hall, T.M.T. Deposit date: 2008-01-11 Release date: 2008-03-11 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p Nat.Struct.Mol.Biol., 15, 2008
6CC1	Crystal structure of ykoY-alx riboswitch chimera bound to cadmium Descriptor: BARIUM ION, CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Bachas, S.T, Ferre-D'amare, A.R. Deposit date: 2018-02-05 Release date: 2018-06-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators. Cell Chem Biol, 25, 2018
2VOO	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-19 Release date: 2008-05-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
4KNQ	Crystal structure of 1nt-5'-overhanging double-helical CCG-repetitive RNA 20mer complexed with RSS p19 Descriptor: 5'-R(P*CP*CP*GP*CP*CP*GP*CP*CP*GP*CP*CP*GP*CP*CP*GP*CP*CP*GP*CP*G)-3', RNA silencing suppressor p19, SULFATE ION Authors: Tamjar, J, Katorcha, E, Popov, A.N, Malinina, L. Deposit date: 2013-05-10 Release date: 2014-05-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Structural insights into CNG-repetitive RNAs associated with human Trinucleotide Repeat Expansion Diseases (TREDs) To be Published
2HCN	Crystal structure of RNA dependent RNA polymerase domain from west nile virus Descriptor: CALCIUM ION, RNA-directed RNA polymerase (NS5), ZINC ION Authors: Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2006-06-17 Release date: 2007-02-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
3C66	Yeast poly(A) polymerase in complex with Fip1 residues 80-105 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ... Authors: Bohm, A, Meinke, G. Deposit date: 2008-02-02 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein. Biochemistry, 47, 2008
3CZ3	Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA Descriptor: Protein 2b, RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*A)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*G)-3') Authors: Ma, J.B, Li, F, Ding, S.W, Patel, D.J. Deposit date: 2008-04-27 Release date: 2009-05-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.23 Å) Cite: Structural Basis for siRNA Recognition by 2b, a Viral Suppressor of Non-Cell Autonomous RNA Silencing To be Published
6IVU	Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum Descriptor: Anti-sigma-I factor RsgI1, RNA polymerase sigma factor SigI1 Authors: Wei, Z, Feng, Y. Deposit date: 2018-12-04 Release date: 2019-05-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Alternative sigma I/anti-sigma I factors represent a unique form of bacterial sigma /anti-sigma complex. Nucleic Acids Res., 47, 2019
8PM4	Cryo-EM structure of the Cas12m-crRNA-target DNA complex Descriptor: DNA oligoduplex, non-target strand, chain D, ... Authors: Sasnauskas, G, Tamulaitiene, G, Karvelis, T, Bigelyte, G, Siksnys, V. Deposit date: 2023-06-28 Release date: 2024-02-07 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing. Nucleic Acids Res., 52, 2024

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