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8EUB
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BU of 8eub by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-18
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVR
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BU of 8evr by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
Descriptor: (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVQ
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BU of 8evq by Molmil
Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVS
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BU of 8evs by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWB
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BU of 8ewb by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-22
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWC
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BU of 8ewc by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure II
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-22
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8F0E
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BU of 8f0e by Molmil
N-terminal WD40 domain of beta'-COPI subunit with four chains in the asymmetric unit
Descriptor: Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-11-02
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
6JLJ
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BU of 6jlj by Molmil
XFEL structure of cyanobacterial photosystem II (dark state, dataset1)
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Suga, M, Shen, J.R.
Deposit date:2019-03-06
Release date:2019-10-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser.
Science, 366, 2019
7VIE
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BU of 7vie by Molmil
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with S1P
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yu, L.Y, Gan, B, Xiao, Q.J, Ren, R.B.
Deposit date:2021-09-26
Release date:2022-09-28
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural insights into sphingosine-1-phosphate receptor activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VIG
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BU of 7vig by Molmil
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CBP-307
Descriptor: 1-[[2-fluoranyl-4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yu, L.Y, Gan, B, Xiao, Q.J, Ren, R.B.
Deposit date:2021-09-26
Release date:2022-09-28
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structural insights into sphingosine-1-phosphate receptor activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VIF
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BU of 7vif by Molmil
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with (S)-FTY720-P
Descriptor: (2~{S})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yu, L.Y, Gan, B, Xiao, Q.J, Ren, R.B.
Deposit date:2021-09-26
Release date:2022-09-28
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structural insights into sphingosine-1-phosphate receptor activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EVL
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BU of 8evl by Molmil
Crystal structure of alpha-COPI N-terminal WD40 domain
Descriptor: Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-10-20
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
7VIH
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BU of 7vih by Molmil
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CBP-307
Descriptor: 1-[[2-fluoranyl-4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yu, L.Y, Gan, B, Xiao, Q.J, Ren, R.B.
Deposit date:2021-09-26
Release date:2022-09-28
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural insights into sphingosine-1-phosphate receptor activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EWX
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BU of 8ewx by Molmil
N-terminal WD40 domain of beta'-COPI subunit with two chains in the asymmetric unit
Descriptor: Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-10-24
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
8EVT
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BU of 8evt by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) refined against a composite map
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
6JLN
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BU of 6jln by Molmil
XFEL structure of cyanobacterial photosystem II (1F state, dataset2)
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Suga, M, Shen, J.R.
Deposit date:2019-03-06
Release date:2019-10-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser.
Science, 366, 2019
7UAS
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BU of 7uas by Molmil
Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization
Descriptor: (5P)-2-[(S)-cyclopropyl(4-methylpyridin-2-yl)methyl]-5-[1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-[(2-methyl-1H-imidazol-1-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one, WD repeat-containing protein 5
Authors:Zhao, B.
Deposit date:2022-03-14
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.808 Å)
Cite:Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization.
J.Med.Chem., 65, 2022
1N2T
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BU of 1n2t by Molmil
C-DES Mutant K223A with GLY Covalenty Linked to the PLP-cofactor
Descriptor: GLYCINE, L-cysteine/cystine lyase C-DES, POTASSIUM ION, ...
Authors:Kaiser, J.T, Bruno, S, Clausen, T, Huber, R, Schiaretti, F, Mozzarelli, A, Kessler, D.
Deposit date:2002-10-24
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Snapshots of the Cystine Lyase "C-DES" during Catalysis: Studies in Solution and in the Crystalline State
J.Biol.Chem., 278, 2003
7UOO
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BU of 7uoo by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
Authors:Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
Deposit date:2022-04-13
Release date:2023-03-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UQZ
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BU of 7uqz by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
Authors:Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
Deposit date:2022-04-20
Release date:2023-03-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7V08
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BU of 7v08 by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
Authors:Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
Deposit date:2022-05-10
Release date:2023-03-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
2XXB
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BU of 2xxb by Molmil
Penta-mutant of Thermus thermophilus lactate dehydrogenase, complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, L-LACTATE DEHYDROGENASE
Authors:Diop, F, Coquelle, N, Vellieux, F.M.D.
Deposit date:2010-11-09
Release date:2010-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Lactate Dehydrogenase from T. Thermophilus, Penta-Mutant (Complex with AMP)
To be Published
8ENZ
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BU of 8enz by Molmil
Crystal structure of alpha-COPI-WD40 domain K15A mutant.
Descriptor: ACETYL GROUP, Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENY
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BU of 8eny by Molmil
Crystal structure of alpha-COPI-WD40 domain R13A mutant.
Descriptor: ACETYL GROUP, Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENX
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BU of 8enx by Molmil
Crystal structure of beta'-COPI-WD40 domain Y33A mutant in complex with SARS-CoV-2 clientized spike tail heptapeptide.
Descriptor: Clientized spike tail heptapeptide, Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023

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数据于2024-07-24公开中

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