7DH5

Dog beta3 adrenergic receptor bound to mirabegron in complex with a miniGs heterotrimer

Summary for 7DH5

Entry DOI	10.2210/pdb7dh5/pdb
EMDB information	30678
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	133110.32
Authors	Shihoya, W.,Yamashita, K.,Nureki, O. (deposition date: 2020-11-12, release date: 2021-08-04, Last modification date: 2021-08-18)
Primary citation	Nagiri, C.,Kobayashi, K.,Tomita, A.,Kato, M.,Kobayashi, K.,Yamashita, K.,Nishizawa, T.,Inoue, A.,Shihoya, W.,Nureki, O. Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity. Mol.Cell, 81:3205-3215.e5, 2021 Cited by PubMed: 34314699 DOI: 10.1016/j.molcel.2021.06.024 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.16 Å)

Structure validation