6XH3
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6XH2
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3VNC
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![BU of 3vnc by Molmil](/molmil-images/mine/3vnc) | Crystal Structure of TIP-alpha N25 from Helicobacter Pylori in its natural dimeric form | Descriptor: | TIP-alpha | Authors: | Gao, M, Li, D, Hu, Y, Zou, Q, Wang, D.-C. | Deposit date: | 2012-01-11 | Release date: | 2012-10-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of TNF-alpha-Inducing Protein from Helicobacter Pylori in Active Form Reveals the Intrinsic Molecular Flexibility for Unique DNA-Binding Plos One, 7, 2012
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1J8D
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6RIB
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6XY7
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![BU of 6xy7 by Molmil](/molmil-images/mine/6xy7) | Human SHIP1 with magnesium and phosphate bound to the active site | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Bradshaw, W.J, Scacioc, A, Fernandez-Cid, A, Mckinley, G, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-29 | Release date: | 2020-02-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.086 Å) | Cite: | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5ES4
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![BU of 5es4 by Molmil](/molmil-images/mine/5es4) | RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Sen, M, Springer, T.A. | Deposit date: | 2015-11-16 | Release date: | 2016-03-02 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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6RIA
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2K2J
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![BU of 2k2j by Molmil](/molmil-images/mine/2k2j) | NMR solution structure of the split PH domain from Phospholipase C gamma 2 | Descriptor: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 | Authors: | Harris, R, Bunney, T.D, Katan, M, Driscoll, P.C. | Deposit date: | 2008-04-02 | Release date: | 2008-09-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Rac Regulates Its Effector Phospholipase C{gamma}2 through Interaction with a Split Pleckstrin Homology Domain. J.Biol.Chem., 283, 2008
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3VVB
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![BU of 3vvb by Molmil](/molmil-images/mine/3vvb) | Crystal Structure of Capsular Polysaccharide Synthesizing Enzyme CapE from Staphylococcus aureus in apo form | Descriptor: | CapE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Miyafusa, T, Caaveiro, J.M, Tanaka, Y, Tsumoto, K. | Deposit date: | 2012-07-18 | Release date: | 2013-06-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus. Biosci.Rep., 33, 2013
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1BRS
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5G0Y
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5I9K
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![BU of 5i9k by Molmil](/molmil-images/mine/5i9k) | The structure of microsomal glutathione transferase 1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTATHIONE, Microsomal glutathione S-transferase 1, ... | Authors: | Kuang, Q, Purhonen, P, Jegerschold, C, Morgenstern, R, Hebert, H. | Deposit date: | 2016-02-20 | Release date: | 2017-07-12 | Last modified: | 2017-08-23 | Method: | ELECTRON CRYSTALLOGRAPHY (3.5 Å) | Cite: | Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation. Sci Rep, 7, 2017
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5IA9
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![BU of 5ia9 by Molmil](/molmil-images/mine/5ia9) | The structure of microsomal glutathione transferase 1 in complex with Meisenheimer complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, Microsomal glutathione S-transferase 1, ... | Authors: | Kuang, Q, Purhonen, P, Jegerschold, C, Morgenstern, R, Hebert, H. | Deposit date: | 2016-02-21 | Release date: | 2017-07-12 | Last modified: | 2017-08-23 | Method: | ELECTRON CRYSTALLOGRAPHY (3.5 Å) | Cite: | Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation. Sci Rep, 7, 2017
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3VVC
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![BU of 3vvc by Molmil](/molmil-images/mine/3vvc) | Crystal Structure of Capsular Polysaccharide Synthesizing Enzyme CapE , K126E, in apo form | Descriptor: | Capsular polysaccharide synthesis enzyme Cap8E, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | Authors: | Miyafusa, T, Caaveiro, J.M, Tanaka, Y, Tsumoto, K. | Deposit date: | 2012-07-18 | Release date: | 2013-06-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus. Biosci.Rep., 33, 2013
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7EG4
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![BU of 7eg4 by Molmil](/molmil-images/mine/7eg4) | Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex | Descriptor: | MAGNESIUM ION, Parvine, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-24 | Release date: | 2021-09-29 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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5G12
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6APO
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![BU of 6apo by Molmil](/molmil-images/mine/6apo) | Anti-Marburgvirus Nucleoprotein Single Domain Antibody A | Descriptor: | Anti-Marburgvirus Nucleoprotein Single Domain Antibody A | Authors: | Taylor, A.B, Garza, J.A. | Deposit date: | 2017-08-17 | Release date: | 2017-10-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.168 Å) | Cite: | Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017
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3W1V
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![BU of 3w1v by Molmil](/molmil-images/mine/3w1v) | Crystal Structure of Capsular Polysaccharide Synthesizing Enzyme CapE from Staphylococcus aureus in complex with inihibitor | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capsular polysaccharide synthesis enzyme Cap8E, SODIUM ION, ... | Authors: | Miyafusa, T, Caaveiro, J.M, Tanaka, Y, Tsumoto, K. | Deposit date: | 2012-11-21 | Release date: | 2013-06-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus. Biosci.Rep., 33, 2013
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7EG0
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![BU of 7eg0 by Molmil](/molmil-images/mine/7eg0) | Cryo-EM structure of anagrelide-induced PDE3A-SLFN12 complex | Descriptor: | 6,7-bis(chloranyl)-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one, MAGNESIUM ION, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-23 | Release date: | 2021-09-29 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7EG1
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![BU of 7eg1 by Molmil](/molmil-images/mine/7eg1) | Cryo-EM structure of DNMDP-induced PDE3A-SLFN12 complex | Descriptor: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-23 | Release date: | 2021-11-03 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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8VUI
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![BU of 8vui by Molmil](/molmil-images/mine/8vui) | Structure of FabS1CE-EPR-1, an elbow-locked Fab, in complex with the erythropoeitin receptor | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... | Authors: | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sidhu, S.S. | Deposit date: | 2024-01-29 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci., 33, 2024
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8VVO
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![BU of 8vvo by Molmil](/molmil-images/mine/8vvo) | Structure of FabS1CE2-EPR1-1 in complex with the erythropoietin receptor | Descriptor: | CHLORIDE ION, Erythropoietin receptor, S1CE2 VARIANT OF FAB-EPR-1 heavy chain, ... | Authors: | Singer, A.U, Bruce, H.A, Pavlenco, A, Ploder, L, Luu, G, Blazer, L, Adams, J.J, Sidhu, S.S. | Deposit date: | 2024-01-31 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci., 33, 2024
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6APQ
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![BU of 6apq by Molmil](/molmil-images/mine/6apq) | Anti-Marburgvirus Nucleoprotein Single Domain Antibody B | Descriptor: | Anti-Marburgvirus Nucleoprotein Single Domain Antibody B, CHLORIDE ION, SODIUM ION | Authors: | Taylor, A.B, Garza, J.A. | Deposit date: | 2017-08-17 | Release date: | 2017-10-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017
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5FTA
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![BU of 5fta by Molmil](/molmil-images/mine/5fta) | Crystal structure of the N-terminal BTB domain of human KCTD10 | Descriptor: | BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3, MERCURY (II) ION | Authors: | Pinkas, D.M, Sanvitale, C.E, Solcan, N, Goubin, S, Tallant, C, Newman, J.A, Kopec, J, Fitzpatrick, F, Talon, R, Collins, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | Deposit date: | 2016-01-12 | Release date: | 2016-02-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases. Biochem. J., 474, 2017
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