7VNP
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![BU of 7vnp by Molmil](/molmil-images/mine/7vnp) | Structure of human KCNQ4-ML213 complex with PIP2 | Descriptor: | (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... | Authors: | Xu, F, Zheng, Y. | Deposit date: | 2021-10-11 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
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6TJ5
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![BU of 6tj5 by Molmil](/molmil-images/mine/6tj5) | T. gondii myosin A trimeric complex with ELC1 | Descriptor: | CALCIUM ION, CHLORIDE ION, Calmodulin, ... | Authors: | Pazicky, S, Loew, C. | Deposit date: | 2019-11-25 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
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4OY4
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![BU of 4oy4 by Molmil](/molmil-images/mine/4oy4) | calcium-free CaMPARI v0.2 | Descriptor: | Chimera protein of Calmodulin, GPF-like protein EosFP, and Myosin light chain kinase, ... | Authors: | Fosque, B.F, Schreiter, E.R. | Deposit date: | 2014-02-10 | Release date: | 2015-02-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators. Science, 347, 2015
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6K67
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![BU of 6k67 by Molmil](/molmil-images/mine/6k67) | Application of anti-helix antibodies in protein structure determination (9011-3LRH) | Descriptor: | 3LRH introbody, CALCIUM ION, Engineered calmodulin | Authors: | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | Deposit date: | 2019-06-01 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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6AYW
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![BU of 6ayw by Molmil](/molmil-images/mine/6ayw) | The structure of human CamKII with bound inhibitor | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Calcium/calmodulin-dependent protein kinase type II subunit delta, N-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamide | Authors: | Somoza, J.R, Villasenor, A.G. | Deposit date: | 2017-09-08 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The structure of human CamKII with bound inhibitor To Be Published
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6NYT
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![BU of 6nyt by Molmil](/molmil-images/mine/6nyt) | Munc13-1 C2B-domain, calcium bound | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | Deposit date: | 2019-02-12 | Release date: | 2019-02-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.369 Å) | Cite: | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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6NYC
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![BU of 6nyc by Molmil](/molmil-images/mine/6nyc) | Munc13-1 C2B-domain, calcium free | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Munc13-1 | Authors: | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | Deposit date: | 2019-02-11 | Release date: | 2019-02-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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6O1U
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![BU of 6o1u by Molmil](/molmil-images/mine/6o1u) | Cryo-EM structure of TRPV5 W583A in nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 5 | Authors: | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | Deposit date: | 2019-02-21 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insight into TRPV5 channel function and modulation. Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1P
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![BU of 6o1p by Molmil](/molmil-images/mine/6o1p) | Cryo-EM structure of full length TRPV5 in nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 5 | Authors: | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | Deposit date: | 2019-02-21 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insight into TRPV5 channel function and modulation. Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1N
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![BU of 6o1n by Molmil](/molmil-images/mine/6o1n) | Cryo-EM structure of TRPV5 (1-660) in nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 5 | Authors: | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | Deposit date: | 2019-02-21 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insight into TRPV5 channel function and modulation. Proc.Natl.Acad.Sci.USA, 116, 2019
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8JFL
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![BU of 8jfl by Molmil](/molmil-images/mine/8jfl) | PhK holoenzyme in active state, muscle isoform | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ... | Authors: | Yang, X.K, Xiao, J.Y. | Deposit date: | 2023-05-18 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
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3WLD
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![BU of 3wld by Molmil](/molmil-images/mine/3wld) | Crystal structure of monomeric GCaMP6m | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | Deposit date: | 2013-11-08 | Release date: | 2014-01-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the ultrasensitive calcium indicator GCaMP6. Sci China Life Sci, 57, 2014
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3WLC
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![BU of 3wlc by Molmil](/molmil-images/mine/3wlc) | Crystal structure of dimeric GCaMP6m | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | Deposit date: | 2013-11-08 | Release date: | 2014-01-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis of the ultrasensitive calcium indicator GCaMP6. Sci China Life Sci, 57, 2014
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3F5G
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![BU of 3f5g by Molmil](/molmil-images/mine/3f5g) | Crystal structure of death associated protein kinase in complex with ADP and Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1, MAGNESIUM ION | Authors: | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | Deposit date: | 2008-11-03 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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3F5U
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![BU of 3f5u by Molmil](/molmil-images/mine/3f5u) | Crystal structure of the death associated protein kinase in complex with AMPPNP and Mg2+ | Descriptor: | Death-associated protein kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | Deposit date: | 2008-11-04 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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2AMI
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![BU of 2ami by Molmil](/molmil-images/mine/2ami) | Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin | Descriptor: | Caltractin | Authors: | Hu, H.T, Fagan, P.A, Bunick, C.G, Sheehan, J.H, Chazin, W.J. | Deposit date: | 2005-08-09 | Release date: | 2005-08-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function. J.Biol.Chem., 281, 2006
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6AUN
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![BU of 6aun by Molmil](/molmil-images/mine/6aun) | calcium-independent phospholipase A2 beta | Descriptor: | PLA2G6, iPLA2beta | Authors: | Malley, K, Koroleva, O, Miller, I, Sanishvili, R, Jenkins, C.M, Gross, R.W, Korolev, S. | Deposit date: | 2017-09-01 | Release date: | 2018-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.951 Å) | Cite: | The structure of iPLA2beta reveals dimeric active sites and suggests mechanisms of regulation and localization. Nat Commun, 9, 2018
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2QG5
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![BU of 2qg5 by Molmil](/molmil-images/mine/2qg5) | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 | Descriptor: | Calcium/calmodulin-dependent protein kinase | Authors: | Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Artz, J, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-28 | Release date: | 2007-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 To be Published
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2RFA
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3EH9
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![BU of 3eh9 by Molmil](/molmil-images/mine/3eh9) | Crystal structure of death associated protein kinase complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1, SULFATE ION | Authors: | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | Deposit date: | 2008-09-11 | Release date: | 2009-04-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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3EHA
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![BU of 3eha by Molmil](/molmil-images/mine/3eha) | |
8XY7
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![BU of 8xy7 by Molmil](/molmil-images/mine/8xy7) | hPhK alpha-gamma subcomplex in active state | Descriptor: | FARNESYL, Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, ... | Authors: | Yang, X.K, Xiao, J.Y. | Deposit date: | 2024-01-19 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
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8TH8
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![BU of 8th8 by Molmil](/molmil-images/mine/8th8) | |
8TID
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![BU of 8tid by Molmil](/molmil-images/mine/8tid) | Combined linker domain of N-DRC and associated proteins Tetrahymena | Descriptor: | AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... | Authors: | Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. | Deposit date: | 2023-07-19 | Release date: | 2023-09-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
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7T6M
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![BU of 7t6m by Molmil](/molmil-images/mine/7t6m) | Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 | Descriptor: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | Deposit date: | 2021-12-14 | Release date: | 2022-05-04 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
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