3OJ2
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2XPP
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![BU of 2xpp by Molmil](/molmil-images/mine/2xpp) | Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form III | Descriptor: | CHROMATIN STRUCTURE MODULATOR, IWS1 | Authors: | Diebold, M.-L, Koch, M, Cura, V, Cavarelli, J, Romier, C. | Deposit date: | 2010-08-27 | Release date: | 2010-11-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
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2HN7
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![BU of 2hn7 by Molmil](/molmil-images/mine/2hn7) | HLA-A*1101 in complex with HBV peptide homologue | Descriptor: | Beta-2-microglobulin, DNA polymerase PEPTIDE HOMOLOGUE, HLA class I histocompatibility antigen, ... | Authors: | Blicher, T. | Deposit date: | 2006-07-12 | Release date: | 2006-11-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue. Acta Crystallogr.,Sect.F, 62, 2006
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2LD5
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![BU of 2ld5 by Molmil](/molmil-images/mine/2ld5) | |
7KK6
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![BU of 7kk6 by Molmil](/molmil-images/mine/7kk6) | |
7KK4
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![BU of 7kk4 by Molmil](/molmil-images/mine/7kk4) | Structure of the catalytic domain of PARP1 in complex with olaparib | Descriptor: | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 1 | Authors: | Gajiwala, K.S, Ryan, K. | Deposit date: | 2020-10-27 | Release date: | 2021-01-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. J.Biol.Chem., 296, 2021
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7KK3
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![BU of 7kk3 by Molmil](/molmil-images/mine/7kk3) | Structure of the catalytic domain of PARP1 in complex with talazoparib | Descriptor: | (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one, Poly [ADP-ribose] polymerase 1 | Authors: | Gajiwala, K.S, Ryan, K. | Deposit date: | 2020-10-27 | Release date: | 2021-01-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. J.Biol.Chem., 296, 2021
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6MQ5
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![BU of 6mq5 by Molmil](/molmil-images/mine/6mq5) | Structure of human CLASP1 TOG1 | Descriptor: | CLIP-associating protein 1 | Authors: | Leano, J.B, Slep, K.C. | Deposit date: | 2018-10-09 | Release date: | 2019-07-17 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.146 Å) | Cite: | Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1. Plos One, 14, 2019
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6TNH
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![BU of 6tnh by Molmil](/molmil-images/mine/6tnh) | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ... | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2019-12-08 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
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1PFN
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![BU of 1pfn by Molmil](/molmil-images/mine/1pfn) | PF4-M2 CHIMERIC MUTANT WITH THE FIRST 10 N-TERMINAL RESIDUES OF R-PF4 REPLACED BY THE N-TERMINAL RESIDUES OF THE IL8 SEQUENCE. MODELS 16-27 OF A 27-MODEL SET. | Descriptor: | PF4-M2 CHIMERA | Authors: | Mayo, K.H, Roongta, V, Ilyina, E, Milius, R, Barker, S, Quinlan, C, La Rosa, G, Daly, T.J. | Deposit date: | 1995-07-18 | Release date: | 1996-01-29 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer. Biochemistry, 34, 1995
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1PFM
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![BU of 1pfm by Molmil](/molmil-images/mine/1pfm) | PF4-M2 CHIMERIC MUTANT WITH THE FIRST 10 N-TERMINAL RESIDUES OF R-PF4 REPLACED BY THE N-TERMINAL RESIDUES OF THE IL8 SEQUENCE. MODELS 1-15 OF A 27-MODEL SET. | Descriptor: | PF4-M2 CHIMERA | Authors: | Mayo, K.H, Roongta, V, Ilyina, E, Milius, R, Barker, S, Quinlan, C, La Rosa, G, Daly, T.J. | Deposit date: | 1995-07-18 | Release date: | 1996-01-29 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer. Biochemistry, 34, 1995
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2HDD
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![BU of 2hdd by Molmil](/molmil-images/mine/2hdd) | ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX | Descriptor: | DNA (5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*C P*CP*GP*GP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN Q50K) | Authors: | Tucker-Kellogg, L, Rould, M.A, Chambers, K.A, Ades, S.E, Sauer, R.T, Pabo, C.O. | Deposit date: | 1998-02-10 | Release date: | 1998-05-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity. Structure, 5, 1997
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7KK2
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![BU of 7kk2 by Molmil](/molmil-images/mine/7kk2) | Structure of the catalytic domain of PARP1 | Descriptor: | Poly [ADP-ribose] polymerase 1, SULFATE ION | Authors: | Gajiwala, K.S, Ryan, K. | Deposit date: | 2020-10-27 | Release date: | 2021-01-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.695 Å) | Cite: | Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. J.Biol.Chem., 296, 2021
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7KK5
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1H3O
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![BU of 1h3o by Molmil](/molmil-images/mine/1h3o) | Crystal Structure of the Human TAF4-TAF12 (TAFII135-TAFII20) Complex | Descriptor: | TRANSCRIPTION INITIATION FACTOR TFIID 135 KDA SUBUNIT, TRANSCRIPTION INITIATION FACTOR TFIID 20/15 KDA SUBUNITS | Authors: | Werten, S, Mitschler, A, Moras, D. | Deposit date: | 2002-09-12 | Release date: | 2002-09-26 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-Associated Factors Htaf4 (Htaf(II)135) and Htaf12 (Htaf(II)20). J.Biol.Chem., 277, 2002
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1P7I
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![BU of 1p7i by Molmil](/molmil-images/mine/1p7i) | CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1P7J
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![BU of 1p7j by Molmil](/molmil-images/mine/1p7j) | Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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4BZ8
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![BU of 4bz8 by Molmil](/molmil-images/mine/4bz8) | Crystal structure of Schistosoma mansoni HDAC8 complexed with J1038 | Descriptor: | (2R)-2-methyl-3-oxo-4H-1,4-benzothiazine-6-carbohydroxamic acid, HISTONE DEACETYLASE 8, POTASSIUM ION, ... | Authors: | Marek, M, Romier, C. | Deposit date: | 2013-07-24 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni. Plos Pathog., 9, 2013
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4BZ9
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![BU of 4bz9 by Molmil](/molmil-images/mine/4bz9) | Crystal structure of Schistosoma mansoni HDAC8 complexed with J1075 | Descriptor: | 3-chlorobenzothiophene-2-carbohydroxamic acid, DIMETHYLFORMAMIDE, GLYCEROL, ... | Authors: | Marek, M, Romier, C. | Deposit date: | 2013-07-24 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni. Plos Pathog., 9, 2013
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4BZ5
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![BU of 4bz5 by Molmil](/molmil-images/mine/4bz5) | Crystal structure of Schistosoma mansoni HDAC8 | Descriptor: | HISTONE DEACETYLASE 8, L(+)-TARTARIC ACID, POTASSIUM ION, ... | Authors: | Marek, M, Romier, C. | Deposit date: | 2013-07-24 | Release date: | 2013-08-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.785 Å) | Cite: | Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni. Plos Pathog., 9, 2013
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4KM9
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![BU of 4km9 by Molmil](/molmil-images/mine/4km9) | |
1XFX
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![BU of 1xfx by Molmil](/molmil-images/mine/1xfx) | Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride | Descriptor: | CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ... | Authors: | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | Deposit date: | 2004-09-15 | Release date: | 2005-05-03 | Last modified: | 2017-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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1XFZ
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![BU of 1xfz by Molmil](/molmil-images/mine/1xfz) | Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride | Descriptor: | CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ... | Authors: | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | Deposit date: | 2004-09-15 | Release date: | 2005-05-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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4HEO
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![BU of 4heo by Molmil](/molmil-images/mine/4heo) | |
1XFU
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![BU of 1xfu by Molmil](/molmil-images/mine/1xfu) | Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin | Descriptor: | CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ... | Authors: | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | Deposit date: | 2004-09-15 | Release date: | 2005-05-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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