PDB: 2894 resultsInfo pagesStatus searchChemie searchBIRD

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6WCB	Human open state TMEM175 in CsCl Descriptor: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175 Authors: Oh, S, Paknejad, N, Hite, R.K. Deposit date: 2020-03-30 Release date: 2020-04-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Gating and selectivity mechanisms for the lysosomal K + channel TMEM175. Elife, 9, 2020
4QE7	Open MthK pore structure soaked in 10 mM Ba2+/100 mM Na+ Descriptor: BARIUM ION, Calcium-gated potassium channel MthK Authors: Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. Deposit date: 2014-05-15 Release date: 2014-07-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
6WCC	Human closed state TMEM175 in CsCl Descriptor: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175 Authors: Oh, S, Paknejad, N, Hite, R.K. Deposit date: 2020-03-30 Release date: 2020-04-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Gating and selectivity mechanisms for the lysosomal K + channel TMEM175. Elife, 9, 2020
4NPQ	The resting-state conformation of the GLIC ligand-gated ion channel Descriptor: Proton-gated ion channel Authors: Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M. Deposit date: 2013-11-22 Release date: 2013-12-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (4.35 Å) Cite: Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111, 2014
6Q6C	Pore-modulating toxins exploit inherent slow inactivation to block K+ channels Descriptor: 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... Authors: Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. Deposit date: 2018-12-10 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
3U6N	Open Structure of the BK channel Gating Ring Descriptor: CALCIUM ION, High-Conductance Ca2+-Activated K+ Channel protein Authors: Yuan, P, MacKinnon, R. Deposit date: 2011-10-12 Release date: 2011-12-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.61 Å) Cite: Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel. Nature, 481, 2011
4ILB	The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Corringer, P.J, Delarue, M. Deposit date: 2012-12-29 Release date: 2013-02-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
2GIZ	Structural and functional analysis of Natrin, a member of crisp-3 family blocks a variety of ion channels Descriptor: Natrin-1 Authors: Jiang, T, Wang, F, Li, H, Yin, C, Zhou, Y, Shu, Y, Qi, Z, Lin, Z. Deposit date: 2006-03-30 Release date: 2006-11-28 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structural and functional analysis of natrin, a venom protein that targets various ion channels Biochem.Biophys.Res.Commun., 351, 2006
4HFH	The GLIC pentameric Ligand-Gated Ion Channel (wild-type) complexed to bromoform Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
4HFC	The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to 2-bromo-ethanol Descriptor: 2-BROMOETHANOL, ACETATE ION, CHLORIDE ION, ... Authors: Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
4HFB	The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant (Apo) Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
4HFD	The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to bromoform Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
4ILC	The GLIC pentameric ligand-gated ion channel in complex with sulfates Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M. Deposit date: 2012-12-29 Release date: 2013-02-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
4HFE	The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to ethanol Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
4ILA	The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium Descriptor: ACETATE ION, CESIUM ION, CHLORIDE ION, ... Authors: Sauguet, L, Corringer, P.J, Delarue, M. Deposit date: 2012-12-29 Release date: 2013-02-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
4IL4	The pentameric ligand-gated ion channel GLIC in complex with Se-DDM Descriptor: ACETATE ION, CHLORIDE ION, Proton-gated ion channel, ... Authors: Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M. Deposit date: 2012-12-29 Release date: 2013-02-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
4IL9	The pentameric ligand-gated ion channel GLIC A237F in complex with bromide Descriptor: ACETATE ION, BROMIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Corringer, P.J, Delarue, M. Deposit date: 2012-12-29 Release date: 2013-02-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
4HFI	The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sauguet, L, Corringer, P.J, Delarue, M. Deposit date: 2012-10-05 Release date: 2013-02-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
3LSV	Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus Descriptor: Ligand-gated ion channel Authors: Nury, H, Corringer, P.J, Delarue, M. Deposit date: 2010-02-13 Release date: 2010-04-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.15 Å) Cite: One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc.Natl.Acad.Sci.USA, 107, 2010
8DGK	NMR structure of calmodulin bound to N-terminal site in the beta-subunit of cyclic nucleotide-gated channel Descriptor: Calmodulin-1, Cyclic nucleotide-gated cation channel beta-1 Authors: Bej, A, Ames, J.B. Deposit date: 2022-06-23 Release date: 2022-12-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR Structures of Calmodulin Bound to Two Separate Regulatory Sites in the Retinal Cyclic Nucleotide-Gated Channel. Biochemistry, 61, 2022
6B8L	Crystal Structure of the Apo/CaM:Kv7.4 (KCNQ4) AB Domain Complex Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 4, SULFATE ION Authors: Chang, A, Abderemane-Ali, F, Minor, D.L. Deposit date: 2017-10-09 Release date: 2018-03-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function Neuron, 97, 2018
8DGH	NMR Structure of calmodulin bound to C-terminal site in the beta-subunit of cyclic nucleotide-gated channel Descriptor: Calmodulin-1, Cyclic nucleotide-gated cation channel beta-1 Authors: Bej, A, Ames, J.B. Deposit date: 2022-06-23 Release date: 2022-12-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR Structures of Calmodulin Bound to Two Separate Regulatory Sites in the Retinal Cyclic Nucleotide-Gated Channel. Biochemistry, 61, 2022
2IBY	Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ... Authors: Haapalainen, A.M, Wierenga, R.K. Deposit date: 2006-09-12 Release date: 2007-04-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function Biochemistry, 46, 2007
6Q61	Pore-modulating toxins exploit inherent slow inactivation to block K+ channels Descriptor: Kunitz-type conkunitzin-S1, SULFATE ION Authors: Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. Deposit date: 2018-12-10 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
5YE2	mammalian endo-lysosomal TRPML1 channel inserting into amphipol Descriptor: mammalian endo-lysosomal TRPML1 channel Authors: Yang, M, Gao, N. Deposit date: 2017-09-15 Release date: 2017-12-27 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017

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