4NPQ

The resting-state conformation of the GLIC ligand-gated ion channel

Summary for 4NPQ

• Entry DOI: 10.2210/pdb4npq/pdb
• Related: 4NPP
• Descriptor: Proton-gated ion channel (1 entity in total)
• Functional Keywords: pentameric ligand-gated ion channel, ph-gated, transmembrane, transport protein
• Biological source: Gloeobacter violaceus
• Cellular location: Cell inner membrane ; Multi- pass membrane protein : Q7NDN8
• Total number of polymer chains: 20
• Total formula weight: 726976.10

Authors

Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M. (deposition date: 2013-11-22, release date: 2013-12-25, Last modification date: 2023-09-20)

• Primary citation: Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M.; Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.; Proc.Natl.Acad.Sci.USA, 111:966-971, 2014; PubMed: 24367074; DOI: 10.1073/pnas.1314997111

Experimental method

X-RAY DIFFRACTION (4.35 Å)