4NPQ

The resting-state conformation of the GLIC ligand-gated ion channel

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005267	molecular_function	potassium channel activity
A	0005272	molecular_function	sodium channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006813	biological_process	potassium ion transport
A	0006814	biological_process	sodium ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0071805	biological_process	potassium ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005267	molecular_function	potassium channel activity
B	0005272	molecular_function	sodium channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006813	biological_process	potassium ion transport
B	0006814	biological_process	sodium ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0071805	biological_process	potassium ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005267	molecular_function	potassium channel activity
C	0005272	molecular_function	sodium channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006813	biological_process	potassium ion transport
C	0006814	biological_process	sodium ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0035725	biological_process	sodium ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0071805	biological_process	potassium ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005267	molecular_function	potassium channel activity
D	0005272	molecular_function	sodium channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0006813	biological_process	potassium ion transport
D	0006814	biological_process	sodium ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0035725	biological_process	sodium ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0071805	biological_process	potassium ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005267	molecular_function	potassium channel activity
E	0005272	molecular_function	sodium channel activity
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0006813	biological_process	potassium ion transport
E	0006814	biological_process	sodium ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0035725	biological_process	sodium ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0071805	biological_process	potassium ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0005267	molecular_function	potassium channel activity
F	0005272	molecular_function	sodium channel activity
F	0005886	cellular_component	plasma membrane
F	0006811	biological_process	monoatomic ion transport
F	0006813	biological_process	potassium ion transport
F	0006814	biological_process	sodium ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0035725	biological_process	sodium ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0071805	biological_process	potassium ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0005267	molecular_function	potassium channel activity
G	0005272	molecular_function	sodium channel activity
G	0005886	cellular_component	plasma membrane
G	0006811	biological_process	monoatomic ion transport
G	0006813	biological_process	potassium ion transport
G	0006814	biological_process	sodium ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0035725	biological_process	sodium ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0071805	biological_process	potassium ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0005267	molecular_function	potassium channel activity
H	0005272	molecular_function	sodium channel activity
H	0005886	cellular_component	plasma membrane
H	0006811	biological_process	monoatomic ion transport
H	0006813	biological_process	potassium ion transport
H	0006814	biological_process	sodium ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0035725	biological_process	sodium ion transmembrane transport
H	0042802	molecular_function	identical protein binding
H	0071805	biological_process	potassium ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0005267	molecular_function	potassium channel activity
I	0005272	molecular_function	sodium channel activity
I	0005886	cellular_component	plasma membrane
I	0006811	biological_process	monoatomic ion transport
I	0006813	biological_process	potassium ion transport
I	0006814	biological_process	sodium ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0035725	biological_process	sodium ion transmembrane transport
I	0042802	molecular_function	identical protein binding
I	0071805	biological_process	potassium ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0005267	molecular_function	potassium channel activity
J	0005272	molecular_function	sodium channel activity
J	0005886	cellular_component	plasma membrane
J	0006811	biological_process	monoatomic ion transport
J	0006813	biological_process	potassium ion transport
J	0006814	biological_process	sodium ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0035725	biological_process	sodium ion transmembrane transport
J	0042802	molecular_function	identical protein binding
J	0071805	biological_process	potassium ion transmembrane transport
K	0004888	molecular_function	transmembrane signaling receptor activity
K	0005216	molecular_function	monoatomic ion channel activity
K	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
K	0005267	molecular_function	potassium channel activity
K	0005272	molecular_function	sodium channel activity
K	0005886	cellular_component	plasma membrane
K	0006811	biological_process	monoatomic ion transport
K	0006813	biological_process	potassium ion transport
K	0006814	biological_process	sodium ion transport
K	0016020	cellular_component	membrane
K	0034220	biological_process	monoatomic ion transmembrane transport
K	0035725	biological_process	sodium ion transmembrane transport
K	0042802	molecular_function	identical protein binding
K	0071805	biological_process	potassium ion transmembrane transport
L	0004888	molecular_function	transmembrane signaling receptor activity
L	0005216	molecular_function	monoatomic ion channel activity
L	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
L	0005267	molecular_function	potassium channel activity
L	0005272	molecular_function	sodium channel activity
L	0005886	cellular_component	plasma membrane
L	0006811	biological_process	monoatomic ion transport
L	0006813	biological_process	potassium ion transport
L	0006814	biological_process	sodium ion transport
L	0016020	cellular_component	membrane
L	0034220	biological_process	monoatomic ion transmembrane transport
L	0035725	biological_process	sodium ion transmembrane transport
L	0042802	molecular_function	identical protein binding
L	0071805	biological_process	potassium ion transmembrane transport
M	0004888	molecular_function	transmembrane signaling receptor activity
M	0005216	molecular_function	monoatomic ion channel activity
M	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
M	0005267	molecular_function	potassium channel activity
M	0005272	molecular_function	sodium channel activity
M	0005886	cellular_component	plasma membrane
M	0006811	biological_process	monoatomic ion transport
M	0006813	biological_process	potassium ion transport
M	0006814	biological_process	sodium ion transport
M	0016020	cellular_component	membrane
M	0034220	biological_process	monoatomic ion transmembrane transport
M	0035725	biological_process	sodium ion transmembrane transport
M	0042802	molecular_function	identical protein binding
M	0071805	biological_process	potassium ion transmembrane transport
N	0004888	molecular_function	transmembrane signaling receptor activity
N	0005216	molecular_function	monoatomic ion channel activity
N	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
N	0005267	molecular_function	potassium channel activity
N	0005272	molecular_function	sodium channel activity
N	0005886	cellular_component	plasma membrane
N	0006811	biological_process	monoatomic ion transport
N	0006813	biological_process	potassium ion transport
N	0006814	biological_process	sodium ion transport
N	0016020	cellular_component	membrane
N	0034220	biological_process	monoatomic ion transmembrane transport
N	0035725	biological_process	sodium ion transmembrane transport
N	0042802	molecular_function	identical protein binding
N	0071805	biological_process	potassium ion transmembrane transport
O	0004888	molecular_function	transmembrane signaling receptor activity
O	0005216	molecular_function	monoatomic ion channel activity
O	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
O	0005267	molecular_function	potassium channel activity
O	0005272	molecular_function	sodium channel activity
O	0005886	cellular_component	plasma membrane
O	0006811	biological_process	monoatomic ion transport
O	0006813	biological_process	potassium ion transport
O	0006814	biological_process	sodium ion transport
O	0016020	cellular_component	membrane
O	0034220	biological_process	monoatomic ion transmembrane transport
O	0035725	biological_process	sodium ion transmembrane transport
O	0042802	molecular_function	identical protein binding
O	0071805	biological_process	potassium ion transmembrane transport
P	0004888	molecular_function	transmembrane signaling receptor activity
P	0005216	molecular_function	monoatomic ion channel activity
P	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
P	0005267	molecular_function	potassium channel activity
P	0005272	molecular_function	sodium channel activity
P	0005886	cellular_component	plasma membrane
P	0006811	biological_process	monoatomic ion transport
P	0006813	biological_process	potassium ion transport
P	0006814	biological_process	sodium ion transport
P	0016020	cellular_component	membrane
P	0034220	biological_process	monoatomic ion transmembrane transport
P	0035725	biological_process	sodium ion transmembrane transport
P	0042802	molecular_function	identical protein binding
P	0071805	biological_process	potassium ion transmembrane transport
Q	0004888	molecular_function	transmembrane signaling receptor activity
Q	0005216	molecular_function	monoatomic ion channel activity
Q	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Q	0005267	molecular_function	potassium channel activity
Q	0005272	molecular_function	sodium channel activity
Q	0005886	cellular_component	plasma membrane
Q	0006811	biological_process	monoatomic ion transport
Q	0006813	biological_process	potassium ion transport
Q	0006814	biological_process	sodium ion transport
Q	0016020	cellular_component	membrane
Q	0034220	biological_process	monoatomic ion transmembrane transport
Q	0035725	biological_process	sodium ion transmembrane transport
Q	0042802	molecular_function	identical protein binding
Q	0071805	biological_process	potassium ion transmembrane transport
R	0004888	molecular_function	transmembrane signaling receptor activity
R	0005216	molecular_function	monoatomic ion channel activity
R	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
R	0005267	molecular_function	potassium channel activity
R	0005272	molecular_function	sodium channel activity
R	0005886	cellular_component	plasma membrane
R	0006811	biological_process	monoatomic ion transport
R	0006813	biological_process	potassium ion transport
R	0006814	biological_process	sodium ion transport
R	0016020	cellular_component	membrane
R	0034220	biological_process	monoatomic ion transmembrane transport
R	0035725	biological_process	sodium ion transmembrane transport
R	0042802	molecular_function	identical protein binding
R	0071805	biological_process	potassium ion transmembrane transport
S	0004888	molecular_function	transmembrane signaling receptor activity
S	0005216	molecular_function	monoatomic ion channel activity
S	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
S	0005267	molecular_function	potassium channel activity
S	0005272	molecular_function	sodium channel activity
S	0005886	cellular_component	plasma membrane
S	0006811	biological_process	monoatomic ion transport
S	0006813	biological_process	potassium ion transport
S	0006814	biological_process	sodium ion transport
S	0016020	cellular_component	membrane
S	0034220	biological_process	monoatomic ion transmembrane transport
S	0035725	biological_process	sodium ion transmembrane transport
S	0042802	molecular_function	identical protein binding
S	0071805	biological_process	potassium ion transmembrane transport
T	0004888	molecular_function	transmembrane signaling receptor activity
T	0005216	molecular_function	monoatomic ion channel activity
T	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
T	0005267	molecular_function	potassium channel activity
T	0005272	molecular_function	sodium channel activity
T	0005886	cellular_component	plasma membrane
T	0006811	biological_process	monoatomic ion transport
T	0006813	biological_process	potassium ion transport
T	0006814	biological_process	sodium ion transport
T	0016020	cellular_component	membrane
T	0034220	biological_process	monoatomic ion transmembrane transport
T	0035725	biological_process	sodium ion transmembrane transport
T	0042802	molecular_function	identical protein binding
T	0071805	biological_process	potassium ion transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1480
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	140
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---