4HFC
The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to 2-bromo-ethanol
Summary for 4HFC
Entry DOI | 10.2210/pdb4hfc/pdb |
Related | 4HFB |
Descriptor | Proton-gated ion channel, DODECYL-BETA-D-MALTOSIDE, 2-BROMOETHANOL, ... (8 entities in total) |
Functional Keywords | pentameric transmembrane channel, ion-channel, membrane protein, transport protein |
Biological source | Gloeobacter violaceus |
Cellular location | Cell inner membrane; Multi-pass membrane protein (Probable): Q7NDN8 |
Total number of polymer chains | 5 |
Total formula weight | 188562.28 |
Authors | Sauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M. (deposition date: 2012-10-05, release date: 2013-04-17, Last modification date: 2024-02-28) |
Primary citation | Sauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4:1697-1697, 2013 Cited by PubMed: 23591864DOI: 10.1038/ncomms2682 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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