4HFC
The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to 2-bromo-ethanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Proton-gated ion channel | polymer | 317 | 36215.7 | 5 | UniProt (Q7NDN8) Pfam (PF02931) | Gloeobacter violaceus | GLIC, Ligand-gated ion channel, LGIC |
| 2 | AA, F, GA, N, U... (D, A, E, B, C) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 6 | Chemie (LMT) | |||
| 3 | DA, G, KA, P, X (D, A, E, B, C) | 2-BROMOETHANOL | non-polymer | 125.0 | 5 | Chemie (BRJ) | |||
| 4 | BA, H, HA, I, J... (D, A, E, B, C) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 5 | EA, K, L, LA, S... (D, A, E, B, C) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 6 | FA, M, MA, T, Z (D, A, E, B, C) | DIUNDECYL PHOSPHATIDYL CHOLINE | non-polymer | 622.8 | 5 | Chemie (PLC) | |||
| 7 | CA, IA, JA, Q, R (D, E, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 8 | NA, OA, PA, QA, RA (A, B, C, D, E) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Ala 238 | Phe 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181078.3 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 7484.0 | |
| All* | Total formula weight | 188562.3 |
