PDB: 183105 resultsInfo pagesStatus searchChemie searchBIRD

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7LAI	Crystal structure of the first bromodomain (BD1) of human BRD2 bound to BI2536 Descriptor: 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Bromodomain-containing protein 2 Authors: Karim, M.R, Bikowitz, M, Schonbrunn, E. Deposit date: 2021-01-06 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J.Med.Chem., 64, 2021
6KBY	Crystal structure of a class C beta lactamase in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, Beta-lactamase Authors: Bae, D.W, Jung, Y.E, An, Y.J, Na, J.H, Cha, S.S. Deposit date: 2019-06-26 Release date: 2019-10-16 Last modified: 2019-11-06 Method: X-RAY DIFFRACTION (1.097 Å) Cite: Structural Insights into Catalytic Relevances of Substrate Poses in ACC-1. Antimicrob.Agents Chemother., 63, 2019
8SD7	Carbonic anhydrase II radiation damage RT 61-90 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.704 Å) Cite: XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024
8SD6	Carbonic anhydrase II radiation damage RT 31-60 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.397 Å) Cite: XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024
8SD9	Carbonic anhydrase II radiation damage RT 121-150 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.904 Å) Cite: XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024
8SAF	CA II in complex with the coumarin benzene sulfonamide SG1-51 Descriptor: 2-[(2-oxo-3,4-dihydro-2H-1-benzopyran-7-yl)oxy]-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-03-31 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (1.23 Å) Cite: CA in complex with novel coumarin benzene sulfonamides To Be Published
8S03	NMR solution structure of the CysD2 domain of MUC2 Descriptor: CALCIUM ION, Mucin-2 Authors: Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. Deposit date: 2024-02-13 Release date: 2024-04-17 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. Cell Rep, 43, 2024
8SF1	Carbonic anhydrase II XFEL radiation damage RT Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-04-10 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024
8SD8	Carbonic anhydrase II radiation damage RT 91-120 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Combs, J.E, Mckenna, R. Deposit date: 2023-04-06 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.789 Å) Cite: XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024
8SH4	Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum Descriptor: GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase Authors: Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. Deposit date: 2023-04-13 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum To Be Published
7LL4	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-114. Descriptor: Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[3-fluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-02-03 Release date: 2022-01-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.31 Å) Cite: High-resolution crystal structure of human Janus Kinase 2 kinase domain (JH1) bound to PN5-114. To Be Published
7LB3	Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580 Descriptor: 1,2-ETHANEDIOL, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole, Transcription initiation factor TFIID subunit 1 Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-01-07 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580 To Be Published
7LL5	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. Descriptor: 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-02-03 Release date: 2022-01-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.5 Å) Cite: High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. To Be Published
7LVE	Jug r 2 Leader Sequence Residues 117-161 Descriptor: Vicilin Jug r 2.0101 Authors: Mueller, G.A, Foo, A.C.Y, DeRose, E.F. Deposit date: 2021-02-25 Release date: 2022-02-02 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
8SG3	High Affinity nanobodies against GFP Descriptor: Green fluorescent protein, LaG41 Authors: Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C. Deposit date: 2023-04-11 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (3.11 Å) Cite: High Affinity nanobodies against GFP To Be Published
8ROZ	Cryo-EM structure of CDK2-cyclin A in complex with CDC25A Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, M-phase inducer phosphatase 1 Authors: Rowland, R.J, Noble, M.E.M, Endicott, J.A. Deposit date: 2024-01-12 Release date: 2024-05-29 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo-EM structure of the CDK2-cyclin A-CDC25A Complex To Be Published
7LDF	High resolution NMR solution structure of a de novo designed minimal thioredoxin fold protein Descriptor: Minimal thioredoxin fold protein, ems_thioM_802 Authors: Urbauer, J.L, Strauch, E.M. Deposit date: 2021-01-13 Release date: 2022-07-13 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Sampling of structure and sequence space of small protein folds. Nat Commun, 13, 2022
7LGL	Structural characterization of two b-KTx scorpion toxins. One of them blocks human KCNQ1 potassium channels Descriptor: Potassium channel toxin TcoKIK Authors: del Rio-Portilla, F, Lopez-Giraldo, A.E. Deposit date: 2021-01-20 Release date: 2021-12-29 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: b-KTx scorpion toxin blocks human KCNQ1 potassium channels To Be Published
7LUW	Structural studies about ScnTx neurotoxin using Solution NMR 2D and 3D Descriptor: Short-chain neurotoxin Authors: del Rio-Portilla, F, Lopez-Giraldo, A.E. Deposit date: 2021-02-23 Release date: 2021-04-14 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The Three-Dimensional Structure of the Neurotoxin SCNTX To Be Published
7LI2	Omega ester peptide pre-fuscimiditide Descriptor: Pre-fuscimiditide peptide Authors: Link, A.J, Elashal, H.E. Deposit date: 2021-01-26 Release date: 2022-02-09 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide. Nat.Chem., 14, 2022
7LXC	Structure and Interactions of DED1 of human cFLIP Descriptor: DED1ch Authors: Panaitiu, A.E, Basiashvili, T, Mierke, D.F, Pellegrini, M. Deposit date: 2021-03-03 Release date: 2021-12-01 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: An engineered construct of cFLIP provides insight into DED1 structure and interactions. Structure, 30, 2022
7LVG	Jug r 2 Leader Sequence Residues 69-111 Descriptor: Vicilin Jug r 2.0101 Authors: Mueller, G.A, Foo, A.C.Y, DeRose, E.F. Deposit date: 2021-02-25 Release date: 2022-02-02 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
7LVF	Jug R 2 Leader Sequence Residues 1-57 Descriptor: Vicilin Jug r 2.0101 Authors: Mueller, G.A, Foo, A.C.Y, DeRose, E.F. Deposit date: 2021-02-25 Release date: 2022-02-02 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
7LIF	Aspartimidylated omega ester peptide fuscimiditide Descriptor: Fuscimiditide peptide Authors: Link, A.J, Elashal, H.E. Deposit date: 2021-01-27 Release date: 2022-02-09 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide. Nat.Chem., 14, 2022
7M92	Crystal structure of unknown function protein protein B9J08_000055 Candida auris Descriptor: Homoserine dehydrogenase Authors: Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2021-03-30 Release date: 2021-04-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of unknown function protein protein B9J08_000055 Candida auris To Be Published

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