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4I5H
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BU of 4i5h by Molmil
Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor
Descriptor: Mitogen-activated protein kinase 1, N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide
Authors:Hari, S.B, Maly, D.J, Merritt, E.A.
Deposit date:2012-11-28
Release date:2013-07-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence determinants of a specific inactive protein kinase conformation.
Chem.Biol., 20, 2013
4H3Q
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BU of 4h3q by Molmil
Crystal structure of human ERK2 complexed with a MAPK docking peptide
Descriptor: Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Gogl, G, Toeroe, I, Remenyi, A.
Deposit date:2012-09-14
Release date:2013-02-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase
Acta Crystallogr.,Sect.D, 69, 2013
4H3P
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BU of 4h3p by Molmil
Crystal structure of human ERK2 complexed with a MAPK docking peptide
Descriptor: Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1
Authors:Gogl, G, Toeroe, I, Remenyi, A.
Deposit date:2012-09-14
Release date:2013-02-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase
Acta Crystallogr.,Sect.D, 69, 2013
4H3B
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BU of 4h3b by Molmil
Crystal Structure of JNK3 in Complex with SAB Peptide
Descriptor: Mitogen-activated protein kinase 10, SH3 domain-binding protein 5
Authors:Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
Deposit date:2012-09-13
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012
4H39
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BU of 4h39 by Molmil
Crystal Structure of JNK3 in Complex with JIP1 Peptide
Descriptor: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10
Authors:Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
Deposit date:2012-09-13
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012
4H36
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BU of 4h36 by Molmil
Crystal Structure of JNK3 in Complex with ATF2 Peptide
Descriptor: Cyclic AMP-dependent transcription factor ATF-2, Mitogen-activated protein kinase 10
Authors:Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
Deposit date:2012-09-13
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012
4GVA
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BU of 4gva by Molmil
ADP-bound form of the ERK2 kinase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitogen-activated protein kinase 1
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-30
Release date:2012-09-12
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:ADP-bound form of the ERK2 kinase
TO BE PUBLISHED
4GT3
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BU of 4gt3 by Molmil
ATP-bound form of the ERK2 kinase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-28
Release date:2012-09-12
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:ATP-bound form of the ERK2 kinase
TO BE PUBLISHED
4GSB
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BU of 4gsb by Molmil
Monoclinic crystal form of the apo-ERK2
Descriptor: GLYCEROL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-27
Release date:2012-09-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Monoclinic crystal form of the apo-ERK2
TO BE PUBLISHED
4GGF
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BU of 4ggf by Molmil
Crystal structure of Mn2+ bound calprotectin
Descriptor: CALCIUM ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Damo, S.M, Fritz, G.
Deposit date:2012-08-06
Release date:2013-02-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEO
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BU of 4geo by Molmil
P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A)
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Livnah, O, Tzarum, N.
Deposit date:2012-08-02
Release date:2013-05-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A)
To be Published
4G6O
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BU of 4g6o by Molmil
Crystal Structure of the ERK2
Descriptor: 1,2-ETHANEDIOL, 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-07-19
Release date:2012-09-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the ERK2 complexed with E28
to be published
4G6N
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BU of 4g6n by Molmil
Crystal Structure of the ERK2
Descriptor: 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-07-19
Release date:2012-09-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the ERK2 complexed with EK0
to be published
4FV9
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BU of 4fv9 by Molmil
Crystal Structure of the ERK2 complexed with E71
Descriptor: 1,2-ETHANEDIOL, 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal Structure of the ERK2 complexed with E71
TO BE PUBLISHED
4FV8
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BU of 4fv8 by Molmil
Crystal Structure of the ERK2 complexed with E63
Descriptor: 1,2-ETHANEDIOL, 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the ERK2 complexed with E63
TO BE PUBLISHED
4FV7
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BU of 4fv7 by Molmil
Crystal Structure of the ERK2 complexed with E94
Descriptor: 1,2-ETHANEDIOL, 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile, GLYCEROL, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the ERK2 complexed with E94
TO BE PUBLISHED
4FV6
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BU of 4fv6 by Molmil
Crystal Structure of the ERK2 complexed with E57
Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2S)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the ERK2 complexed with E57
TO BE PUBLISHED
4FV5
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BU of 4fv5 by Molmil
Crystal Structure of the ERK2 complexed with EK9
Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the ERK2 complexed with EK9
TO BE PUBLISHED
4FV4
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BU of 4fv4 by Molmil
Crystal Structure of the ERK2 complexed with EK7
Descriptor: 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile, GLYCEROL, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the ERK2 complexed with EK7
TO BE PUBLISHED
4FV3
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BU of 4fv3 by Molmil
Crystal Structure of the ERK2 complexed with EK6
Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the ERK2 complexed with EK6
TO BE PUBLISHED
4FV2
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BU of 4fv2 by Molmil
Crystal Structure of the ERK2 complexed with EK5
Descriptor: 1,2-ETHANEDIOL, 4-[4-(3-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, GLYCEROL, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-29
Release date:2012-08-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the ERK2 complexed with EK5
TO BE PUBLISHED
4FV1
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BU of 4fv1 by Molmil
Crystal Structure of the ERK2 complexed with EK4
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-28
Release date:2012-08-22
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal Structure of the ERK2 complexed with EK4
TO BE PUBLISHED
4FV0
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BU of 4fv0 by Molmil
Crystal Structure of the ERK2 complexed with EK3
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-28
Release date:2012-08-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the ERK2 complexed with EK3
TO BE PUBLISHED
4FUY
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BU of 4fuy by Molmil
Crystal Structure of the ERK2 complexed with EK2
Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-28
Release date:2012-08-22
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the ERK2 complexed with EK2
TO BE PUBLISHED
4FUX
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BU of 4fux by Molmil
Crystal Structure of the ERK2 complexed with E75
Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Kang, Y.N, Stuckey, J.A, Xie, X.
Deposit date:2012-06-28
Release date:2012-08-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the ERK2 complexed with E75
TO BE PUBLISHED

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