4H3Q

Crystal structure of human ERK2 complexed with a MAPK docking peptide

Summary for 4H3Q

Entry DOI	10.2210/pdb4h3q/pdb
Related	3TEI 4H3P
Descriptor	Mitogen-activated protein kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	kinase domain, signaling, linear motif, surface mutation, transferase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, spindle (By similarity): P28482
Total number of polymer chains	2
Total formula weight	43356.47
Authors	Gogl, G.,Toeroe, I.,Remenyi, A. (deposition date: 2012-09-14, release date: 2013-02-27, Last modification date: 2023-11-08)
Primary citation	Gogl, G.,Toeroe, I.,Remenyi, A. Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase Acta Crystallogr.,Sect.D, 69:486-489, 2013 Cited by PubMed: 23519423 DOI: 10.1107/S0907444912051062 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation