8AAE
 
 | | CAII in complex with para-carboran-propylsulfonamid | | Descriptor: | Carbonic anhydrase 2, Para-Carborane propyl-sulfonamide, ZINC ION | | Authors: | Brynda, J, Rezacova, P. | | Deposit date: | 2022-07-01 | | Release date: | 2023-05-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | B-H⋯ pi and C-H⋯ pi interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.
Phys Chem Chem Phys, 25, 2023
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8AA6
 | | CAII in complex with meta-carboran-propylsulfonamid | | Descriptor: | Carbonic anhydrase 2, ZINC ION, meta-carboran-propylsulfonamid | | Authors: | Brynda, J, Rezacova, P, Kugler, M. | | Deposit date: | 2022-06-30 | | Release date: | 2023-05-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | B-H⋯ pi and C-H⋯ pi interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.
Phys Chem Chem Phys, 25, 2023
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6OQ5
 | | Structure of the full-length Clostridium difficile toxin B in complex with 3 VHHs | | Descriptor: | 5D, 7F, E3, ... | | Authors: | Chen, P, Lam, K, Jin, R. | | Deposit date: | 2019-04-25 | | Release date: | 2019-07-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.87 Å) | | Cite: | Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
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6OQ6
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8BN0
 | | Bacteroides thetaiotaomicron surface protein BT1954 bound to | | Descriptor: | CHLORIDE ION, COB(II)INAMIDE, CYANIDE ION, ... | | Authors: | Abellon-Ruiz, J, Jana, K, Silale, A, Basle, A, Kleinekathofer, U, van den Berg, B. | | Deposit date: | 2022-11-11 | | Release date: | 2023-08-16 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B 12 uptake in gut Bacteroides.
Nat Commun, 14, 2023
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6OQ7
 | | Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3 | | Descriptor: | E3, MAGNESIUM ION, MANGANESE (II) ION, ... | | Authors: | Chen, P, Lam, K, Jin, R. | | Deposit date: | 2019-04-25 | | Release date: | 2019-07-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
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8RMS
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8RN0
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7R59
 | | PARP2 catalytic domain in complex with OUL245 | | Descriptor: | GLYCEROL, Poly [ADP-ribose] polymerase 2, [1,2,4]triazolo[3,4-b][1,3]benzothiazol-6-ol | | Authors: | Galera-Prat, A, Maksimainen, M.M, Lehtio, L. | | Deposit date: | 2022-02-10 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | [1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
J.Med.Chem., 66, 2023
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7R5X
 | | Tankyrase 2 in complex with an inhibitor (OUL211) | | Descriptor: | 7-methyl-[1,2,4]triazolo[3,4-b][1,3]benzothiazole, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... | | Authors: | Sowa, S.T, Lehtio, L. | | Deposit date: | 2022-02-11 | | Release date: | 2023-02-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.052 Å) | | Cite: | [1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
J.Med.Chem., 66, 2023
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7A1Z
 | | Crystal structure of human protein kinase CK2alpha' (CSNK2A2 gene product) in complex with the ATP-competitive inhibitor 6-bromo-5-chloro-1H-triazolo[4,5-b]pyridine | | Descriptor: | 1,2-ETHANEDIOL, 6-bromanyl-5-chloranyl-1~{H}-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | | Authors: | Niefind, K, Lindenblatt, D, Toelzer, C, Bretner, M, Chojnacki, K, Wielechowska, M, Winska, P. | | Deposit date: | 2020-08-14 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.024 Å) | | Cite: | Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase.
Bioorg.Chem., 106, 2021
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8KG5
 | | Prefusion RSV F Bound to Lonafarnib and D25 Fab | | Descriptor: | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ... | | Authors: | Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X. | | Deposit date: | 2023-08-17 | | Release date: | 2024-06-19 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Signal Transduct Target Ther, 9, 2024
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8RMR
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7YSA
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5F5Y
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5LGN
 | | Thieno[3,2-b]pyrrole-5-carboxamides as Novel Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1: Compound 19 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1, ... | | Authors: | Mattevi, A, Ciossani, G. | | Deposit date: | 2016-07-07 | | Release date: | 2017-02-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
J. Med. Chem., 60, 2017
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7OTC
 | | Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B | | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ... | | Authors: | Wieland, M, Koller, T.O, Wilson, D.N. | | Deposit date: | 2021-06-10 | | Release date: | 2022-05-11 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8W5D
 | | Cryo-EM structure of Qb-Ab1 | | Descriptor: | Heavy chain of Ab1, Light chain of Ab1, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hua, Z.L, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-26 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5F
 | | Cryo-EM structure of Qb-Ab6 | | Descriptor: | Heavy chain of Ab6, Light chain of Ab6, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hua, Z.L, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-26 | | Release date: | 2025-02-26 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5V
 | | Cryo-EM structure of QbN10K-Ab40 | | Descriptor: | Heavy chain of Ab40, Light chain of Ab40, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hua, Z.L, Hou, B.D. | | Deposit date: | 2023-08-27 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5P
 | | Cryo-EM structure of Qb-Ab40 | | Descriptor: | Heavy chain of Ab40, Light chain of Ab40, Minor capsid protein A1 | | Authors: | Bao, K.Y, Hua, Z.L, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-27 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5Q
 | | Cryo-EM structure of Qb-Ab45 | | Descriptor: | Heavy chain of Ab45, Light chain of Ab45, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hua, Z.L, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-27 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5E
 | | Cryo-EM structure of Qb-Ab4 | | Descriptor: | Heavy chain of Ab4, Light chain of Ab4, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hua, Z.L, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-26 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8W5U
 | | Cryo-EM structure of QbN10F-Ab40 | | Descriptor: | Heavy chain of Ab40, Light chain of Ab40, Minor capsid protein A1 | | Authors: | Bao, K.Y, Li, R.H, Hou, B.D, Zhu, P. | | Deposit date: | 2023-08-27 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.
Cell Rep, 44, 2025
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8RDF
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