7P70
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![BU of 7p70 by Molmil](/molmil-images/mine/7p70) | The PDZ-domain of SNTB1 complexed with the PDZ-binding motif of HPV35-E6 | Descriptor: | Beta-1-syntrophin,Annexin A2, CALCIUM ION, GLYCEROL, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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6WJ2
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![BU of 6wj2 by Molmil](/molmil-images/mine/6wj2) | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state | Descriptor: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Fromm, S.A, Hurley, J.H. | Deposit date: | 2020-04-11 | Release date: | 2020-09-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. Nat.Struct.Mol.Biol., 27, 2020
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8V87
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![BU of 8v87 by Molmil](/molmil-images/mine/8v87) | 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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8V83
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![BU of 8v83 by Molmil](/molmil-images/mine/8v83) | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. | Deposit date: | 2023-12-04 | Release date: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
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7L08
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![BU of 7l08 by Molmil](/molmil-images/mine/7l08) | Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | Descriptor: | 12S rRNA, 16S RRNA, 28S ribosomal protein S10, ... | Authors: | Koripella, R, Agrawal, E.K, Deep, A, Agrawal, R.K. | Deposit date: | 2020-12-11 | Release date: | 2021-05-12 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance. Nat Commun, 12, 2021
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6XYZ
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![BU of 6xyz by Molmil](/molmil-images/mine/6xyz) | Crystal structure of the GH18 chitinase ChiB from the chitin utilization locus of Flavobacterium johnsoniae | Descriptor: | 1,2-ETHANEDIOL, Candidate chitinase Glycoside hydrolase family 18, FORMIC ACID | Authors: | Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V, Pope, P, Branden, G, Larsbrink, J. | Deposit date: | 2020-01-31 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae. Sci Rep, 10, 2020
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5ECO
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![BU of 5eco by Molmil](/molmil-images/mine/5eco) | Crystal Structure of FIN219-FIP1 complex with JA, Leu and Mg | Descriptor: | GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECH
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![BU of 5ech by Molmil](/molmil-images/mine/5ech) | Crystal Structure of FIN219-FIP1 complex with JA and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECL
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![BU of 5ecl by Molmil](/molmil-images/mine/5ecl) | Crystal Structure of FIN219-FIP1 complex with JA, Ile and Mg | Descriptor: | GLUTATHIONE, Glutathione S-transferase U20, ISOLEUCINE, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ECK
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![BU of 5eck by Molmil](/molmil-images/mine/5eck) | Crystal Structure of FIN219-FIP1 complex with JA, Ile and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ... | Authors: | Chen, C.Y, Cheng, Y.S. | Deposit date: | 2015-10-20 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4KP3
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![BU of 4kp3 by Molmil](/molmil-images/mine/4kp3) | Crystal Structure of MyoVa-GTD in Complex with Two Cargos | Descriptor: | Melanophilin, RILP-like protein 2, Unconventional myosin-Va | Authors: | Wei, Z, Liu, X, Yu, C, Zhang, M. | Deposit date: | 2013-05-13 | Release date: | 2013-07-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.405 Å) | Cite: | Structural basis of cargo recognitions for class V myosins Proc.Natl.Acad.Sci.USA, 110, 2013
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4M6R
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![BU of 4m6r by Molmil](/molmil-images/mine/4m6r) | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme | Descriptor: | Methylthioribulose-1-phosphate dehydratase, ZINC ION | Authors: | Kang, W, Hong, S.H, Lee, H.M, Kim, N.Y, Lim, Y.C, Le, L.T.M, Lim, B, Kim, H.C, Kim, T.Y, Ashida, H, Yokota, A, Hah, S.S, Chun, K.H, Jung, Y.K, Yang, J.K. | Deposit date: | 2013-08-10 | Release date: | 2014-01-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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6YHH
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![BU of 6yhh by Molmil](/molmil-images/mine/6yhh) | X-ray Structure of Flavobacterium johnsoniae chitobiase (FjGH20) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-N-acetylglucosaminidase-like protein Glycoside hydrolase family 20, GLYCEROL | Authors: | Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V.G.H, Pope, P.B, Branden, G, Larsbrink, J. | Deposit date: | 2020-03-30 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae. Sci Rep, 10, 2020
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3VXW
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![BU of 3vxw by Molmil](/molmil-images/mine/3vxw) | |
6ZFN
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![BU of 6zfn by Molmil](/molmil-images/mine/6zfn) | Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with 1-methyl alpha-1,2-mannobiose | Descriptor: | Glycoprotein endo-alpha-1,2-mannosidase, SULFATE ION, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-17 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z9B
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![BU of 6z9b by Molmil](/molmil-images/mine/6z9b) | |
6ZDC
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![BU of 6zdc by Molmil](/molmil-images/mine/6zdc) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with nickel | Descriptor: | Glycoprotein endo-alpha-1,2-mannosidase, NICKEL (II) ION | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-14 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZFQ
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![BU of 6zfq by Molmil](/molmil-images/mine/6zfq) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with bis-tris | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoprotein endo-alpha-1,2-mannosidase | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-17 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z9D
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![BU of 6z9d by Molmil](/molmil-images/mine/6z9d) | |
6ZDK
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![BU of 6zdk by Molmil](/molmil-images/mine/6zdk) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES and hexatungstotellurate(VI) TEW | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-tungstotellurate(VI), Glycoprotein endo-alpha-1,2-mannosidase, ... | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-14 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZJ6
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![BU of 6zj6 by Molmil](/molmil-images/mine/6zj6) | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with cyclohexylmethyl-Glc-1,3-isofagomine | Descriptor: | 1,2-ETHANEDIOL, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ACETATE ION, ... | Authors: | Thompson, A.J, Sobala, L.F, Fernandes, P.Z, Hakki, Z, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-27 | Release date: | 2020-11-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZDL
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![BU of 6zdl by Molmil](/molmil-images/mine/6zdl) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG and hexatungstotellurate(VI) TEW | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-14 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZJ1
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![BU of 6zj1 by Molmil](/molmil-images/mine/6zj1) | Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with tetrasaccharide N-glycan fragment and hexatungstotellurate(VI) TEW | Descriptor: | 6-tungstotellurate(VI), Glycoprotein endo-alpha-1,2-mannosidase, MAGNESIUM ION, ... | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-27 | Release date: | 2020-12-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.957 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZJ5
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![BU of 6zj5 by Molmil](/molmil-images/mine/6zj5) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcDMJ and hexatungstotellurate(VI) TEW | Descriptor: | 1-DEOXYMANNOJIRIMYCIN, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-tungstotellurate(VI), ... | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-27 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.269 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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6FG7
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![BU of 6fg7 by Molmil](/molmil-images/mine/6fg7) | Crystal structure of the BIR2 ectodomain from Arabidopsis thaliana. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Inactive LRR receptor-like serine/threonine-protein kinase BIR2, ... | Authors: | Hothorn, M, Hohmann, U. | Deposit date: | 2018-01-10 | Release date: | 2018-01-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signalling. Nat Plants, 4, 2018
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