7TUJ
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![BU of 7tuj by Molmil](/molmil-images/mine/7tuj) | NMR solution structure of the phosphorylated MUS81-binding region from human SLX4 | Descriptor: | Structure-specific endonuclease subunit SLX4 | Authors: | Payliss, B.J, Reichheld, S.E, Lemak, A, Arrowsmith, C.H, Sharpe, S, Wyatt, H.D.M. | Deposit date: | 2022-02-02 | Release date: | 2022-10-19 | Last modified: | 2022-11-09 | Method: | SOLUTION NMR | Cite: | Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease. Cell Rep, 41, 2022
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5H1H
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![BU of 5h1h by Molmil](/molmil-images/mine/5h1h) | NMR structure of SLBA, a chimera of SFTI | Descriptor: | Bradykinin-trypsin inhibitor secondary loop chimera | Authors: | Xiao, T, Tam, J.P. | Deposit date: | 2016-10-10 | Release date: | 2017-04-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor. J. Med. Chem., 60, 2017
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5H1I
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![BU of 5h1i by Molmil](/molmil-images/mine/5h1i) | NMR structure of TIBA, a chimera of SFTI | Descriptor: | Bradykinin-trypsin inhibitor secondary loop chimera | Authors: | Xiao, T, Tam, J.P. | Deposit date: | 2016-10-10 | Release date: | 2017-04-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor. J. Med. Chem., 60, 2017
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5O2V
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![BU of 5o2v by Molmil](/molmil-images/mine/5o2v) | NMR structure of TIA-1 RRM1 domain | Descriptor: | Nucleolysin TIA-1 isoform p40 | Authors: | Jagtap, P.K.A. | Deposit date: | 2017-05-22 | Release date: | 2017-06-28 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins. Angew. Chem. Int. Ed. Engl., 56, 2017
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5O6F
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![BU of 5o6f by Molmil](/molmil-images/mine/5o6f) | NMR structure of cold shock protein A from Corynebacterium pseudotuberculosis | Descriptor: | Cold-shock protein | Authors: | Caruso, I.P, Panwalkar, V, Coronado, M.A, Dingley, A.J, Cornelio, M.L, Willbold, D, Arni, R.K, Eberle, R.J. | Deposit date: | 2017-06-06 | Release date: | 2017-07-19 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure and interaction of Corynebacterium pseudotuberculosis cold shock protein A with Y-box single-stranded DNA fragment. FEBS J., 285, 2018
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6WUX
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![BU of 6wux by Molmil](/molmil-images/mine/6wux) | |
5IAY
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![BU of 5iay by Molmil](/molmil-images/mine/5iay) | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Spacer | Authors: | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | Deposit date: | 2016-02-22 | Release date: | 2016-04-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
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5IIR
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![BU of 5iir by Molmil](/molmil-images/mine/5iir) | |
5IEW
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![BU of 5iew by Molmil](/molmil-images/mine/5iew) | |
5NR6
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![BU of 5nr6 by Molmil](/molmil-images/mine/5nr6) | |
7X3A
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![BU of 7x3a by Molmil](/molmil-images/mine/7x3a) | NMR solution structure of the 1:1 complex of a pyridostatin (PDS) bound to a G-quadruplex MYT1L | Descriptor: | 4-(2-azanylethoxy)-N2,N6-bis[4-(2-azanylethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide, G-quadruplex DNA MYT1L | Authors: | Liu, L.-Y, Mao, Z.-W, Liu, W. | Deposit date: | 2022-02-28 | Release date: | 2022-06-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes. J.Am.Chem.Soc., 144, 2022
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5B7X
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6MNL
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![BU of 6mnl by Molmil](/molmil-images/mine/6mnl) | |
2G2K
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![BU of 2g2k by Molmil](/molmil-images/mine/2g2k) | NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5) | Descriptor: | Eukaryotic translation initiation factor 5 | Authors: | Conte, M.R, Kelly, G, Babon, J, Sanfelice, D, Smerdon, S.J, Proud, C.G. | Deposit date: | 2006-02-16 | Release date: | 2006-06-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors Biochemistry, 45, 2006
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2GFU
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![BU of 2gfu by Molmil](/molmil-images/mine/2gfu) | NMR solution structure of the PWWP domain of Mismatch repair protein hMSH6 | Descriptor: | DNA mismatch repair protein MSH6 | Authors: | Laguri, C, Friedrich, N, Axt, M, Gilquin, B, Zinn-Justin, S, Couprie, J. | Deposit date: | 2006-03-23 | Release date: | 2007-04-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The PWWP domain of Mismatch Repair protein hMSH6 is involved in double stranded and single stranded DNA binding To be Published
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5UG3
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![BU of 5ug3 by Molmil](/molmil-images/mine/5ug3) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID MUTANT A10V | Descriptor: | Alpha-conotoxin GID | Authors: | Hussein, A.K, Leffler, A.E, Zebroski, H.A, Powell, S.R, Kuryatov, A, Filipenko, P, Gorson, J, Heizmann, A, Lyskov, S, Nicke, A, Lindstrom, J, Rudy, B, Bonneau, R, Holford, M, Poget, S.F. | Deposit date: | 2017-01-06 | Release date: | 2017-09-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UJQ
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![BU of 5ujq by Molmil](/molmil-images/mine/5ujq) | NMR Solution Structure of the Two-component Bacteriocin CbnXY | Descriptor: | Bacteriocin | Authors: | Acedo, J.Z, Towle, K.M, Lohans, C.T, McKay, R.T, Miskolzie, M, Doerksen, T, Vederas, J.C, Martin-Visscher, L.A. | Deposit date: | 2017-01-18 | Release date: | 2017-11-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Identification and three-dimensional structure of carnobacteriocin XY, a class IIb bacteriocin produced by Carnobacteria. FEBS Lett., 591, 2017
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5UJR
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![BU of 5ujr by Molmil](/molmil-images/mine/5ujr) | NMR Solution Structure of the Two-component Bacteriocin CbnXY | Descriptor: | Bacteriocin | Authors: | Acedo, J.Z, Towle, K.M, Lohans, C.T, McKay, R.T, Miskolzie, M, Doerksen, T, Vederas, J.C, Martin-Visscher, L.A. | Deposit date: | 2017-01-18 | Release date: | 2017-11-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Identification and three-dimensional structure of carnobacteriocin XY, a class IIb bacteriocin produced by Carnobacteria. FEBS Lett., 591, 2017
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5ZGG
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![BU of 5zgg by Molmil](/molmil-images/mine/5zgg) | NMR structure of p75NTR transmembrane domain in complex with NSC49652 | Descriptor: | (2E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one, Tumor necrosis factor receptor superfamily member 16 | Authors: | Lin, Z, Ibanez, C. | Deposit date: | 2018-03-08 | Release date: | 2019-03-13 | Last modified: | 2019-09-25 | Method: | SOLUTION NMR | Cite: | A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTRInduces Melanoma Cell Death and Reduces Tumor Growth. Cell Chem Biol, 25, 2018
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5VSO
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![BU of 5vso by Molmil](/molmil-images/mine/5vso) | NMR structure of Ydj1 J-domain, a cytosolic Hsp40 from Saccharomyces cerevisiae | Descriptor: | Yeast dnaJ protein 1 | Authors: | Ciesielski, S.J, Tonelli, M, Lee, W, Cornilescu, G, Markley, J.L, Schilke, B.A, Ziegelhoffer, T, Craig, E.A. | Deposit date: | 2017-05-12 | Release date: | 2017-11-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Broadening the functionality of a J-protein/Hsp70 molecular chaperone system. PLoS Genet., 13, 2017
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7M79
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3ZGP
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![BU of 3zgp by Molmil](/molmil-images/mine/3zgp) | NMR structure of the catalytic domain from E. faecium L,D- transpeptidase acylated by ertapenem | Descriptor: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, ERFK/YBIS/YCFS/YNHG | Authors: | Lecoq, L, Triboulet, S, Dubee, V, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | Deposit date: | 2012-12-18 | Release date: | 2013-04-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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3ZG4
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![BU of 3zg4 by Molmil](/molmil-images/mine/3zg4) | NMR structure of the catalytic domain from E. faecium L,D- transpeptidase | Descriptor: | ERFK/YBIS/YCFS/YNHG | Authors: | Lecoq, L, Dubee, V, Triboulet, S, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | Deposit date: | 2012-12-14 | Release date: | 2013-04-24 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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7OFN
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8K6Z
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![BU of 8k6z by Molmil](/molmil-images/mine/8k6z) | NMR structure of human leptin | Descriptor: | Leptin | Authors: | Fan, X, Qin, R, Yuan, W, Fan, J, Huang, W, Lin, Z. | Deposit date: | 2023-07-26 | Release date: | 2024-02-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The solution structure of human leptin reveals a conformational plasticity important for receptor recognition. Structure, 32, 2024
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