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7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG8
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BU of 7eg8 by Molmil
TFIID-based core PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
5ODD
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BU of 5odd by Molmil
HUMAN MED26 N-TERMINAL DOMAIN (1-92)
Descriptor: Mediator of RNA polymerase II transcription subunit 26
Authors:Lens, Z, Cantrelle, F.-X, Perruzini, R, Dewitte, F, Hanoulle, X, Villeret, V, Verger, A, Landrieu, I.
Deposit date:2017-07-05
Release date:2017-11-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.
Biomol.Nmr Assign., 10, 2016
1DPN
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BU of 1dpn by Molmil
B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Egli, M, Tereshko, V, Teplova, M, Minasov, G, Joachimiak, A, Sanishvili, R, Weeks, C.M, Miller, R, Maier, M.A, An, H, Dan Cook, P, Manoharan, M.
Deposit date:1999-12-27
Release date:2000-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
388D
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BU of 388d by Molmil
CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*(TAF)P*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M.
Deposit date:1998-04-20
Release date:1998-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
389D
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BU of 389d by Molmil
CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M.
Deposit date:1998-04-20
Release date:1998-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
436D
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BU of 436d by Molmil
THE DICKERSON-DREW B-DNA DODECAMER REVISITED-AT ATOMIC RESOLUTION
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Tereshko, V, Minasov, G, Egli, M.
Deposit date:1998-11-12
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Dickerson-Drew B-DNA Dodecamer Revisited-At Atomic Resolution
J.Am.Chem.Soc., 121, 1999
461D
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BU of 461d by Molmil
A "HYDRAT-ION SPINE" IN A B-DNA MINOR GROOVE
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, RUBIDIUM ION
Authors:Tereshko, V, Minasov, G, Egli, M.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A "Hydrat-Ion Spine" in a B-DNA minor groove
J.Am.Chem.Soc., 121, 1999
478D
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BU of 478d by Molmil
CRYSTAL STRUCTURE OF THE B-DNA DODECAMER 5'-D(CGCGAA(TAF)TCGCG), WHERE TAF IS 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3', CALCIUM ION
Authors:Minasov, G, Tereshko, V, Egli, M.
Deposit date:1999-06-26
Release date:1999-07-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing.
J.Mol.Biol., 291, 1999
460D
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BU of 460d by Molmil
A "HYDRAT-ION SPINE" IN A B-DNA MINOR GROOVE
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, RUBIDIUM ION
Authors:Tereshko, V, Minasov, G, Egli, M.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A "Hydrat-Ion Spine" in a B-DNA minor groove
J.Am.Chem.Soc., 121, 1999
2F69
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BU of 2f69 by Molmil
Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Couture, J.-F, Collazo, E, Hauk, G, Trievel, R.C.
Deposit date:2005-11-28
Release date:2006-01-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for the methylation site specificity of SET7/9
Nat.Struct.Mol.Biol., 13, 2006
1FXH
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BU of 1fxh by Molmil
MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE
Descriptor: 2-PHENYLACETIC ACID, CALCIUM ION, PENICILLIN ACYLASE
Authors:Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B.
Deposit date:2000-09-26
Release date:2001-03-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
1FXV
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BU of 1fxv by Molmil
PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE
Descriptor: CALCIUM ION, PENICILLIN ACYLASE, PENICILLIN G
Authors:Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B.
Deposit date:2000-09-27
Release date:2001-03-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
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