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6CO1
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BU of 6co1 by Molmil
Structure of human TIRR in complex with 53BP1 Tudor domains
Descriptor: TP53-binding protein 1, Tudor-interacting repair regulator protein
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2018-03-10
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
5ZCJ
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BU of 5zcj by Molmil
Crystal structure of complex
Descriptor: TP53-binding protein 1, Tudor-interacting repair regulator protein
Authors:Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X.
Deposit date:2018-02-17
Release date:2018-06-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal structure of complex
To Be Published
5Z78
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BU of 5z78 by Molmil
Structure of TIRR/53BP1 complex
Descriptor: TP53-binding protein 1, Tudor-interacting repair regulator protein
Authors:Dai, Y.X, Shan, S.
Deposit date:2018-01-27
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR
Nat Commun, 9, 2018
5J26
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BU of 5j26 by Molmil
Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant
Descriptor: Tumor suppressor p53-binding protein 1, Ubiquitin Variant i53
Authors:Wan, L, Canny, M, Juang, Y.C, Durocher, D, Sicheri, F.
Deposit date:2016-03-29
Release date:2016-12-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5047 Å)
Cite:A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing
To Be Published
7YQK
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BU of 7yqk by Molmil
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
Descriptor: DNA (145-MER), Histone H2AX, Histone H2B, ...
Authors:Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L.
Deposit date:2022-08-07
Release date:2022-08-17
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
J.Am.Chem.Soc., 144, 2022
8SVI
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BU of 8svi by Molmil
Ubiquitin variant i53:Mutant L67H with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin Variant i53: Mutant L67H
Authors:Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVJ
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BU of 8svj by Molmil
Ubiquitin variant i53: mutant VHH with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin varient i53 mutant VHH
Authors:Holden, J, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVG
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BU of 8svg by Molmil
Ubiquitin variant i53 in complex with 53BP1 Tudor domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8T2D
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BU of 8t2d by Molmil
Ubiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53
Authors:Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
Deposit date:2023-06-05
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVH
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BU of 8svh by Molmil
Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53: mutant L67R
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
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数据于2024-10-16公开中

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