8BRJ
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-23 | Release date: | 2023-05-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.08 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BNU
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-14 | Release date: | 2023-05-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BNR
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-14 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (10.3 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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5CBQ
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5XZ5
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1PXT
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1DLV
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1OU6
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7FEA
| PY14 in complex with Col-D | Descriptor: | (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase | Authors: | Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors. Commun Biol, 5, 2022
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5ZQZ
| Structure of human mitochondrial trifunctional protein, tetramer | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | Authors: | Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J. | Deposit date: | 2018-04-20 | Release date: | 2018-06-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of human mitochondrial trifunctional protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5BYV
| Crystal structure of MSM-13, a putative T1-like thiolase from Mycobacterium smegmatis | Descriptor: | Beta-ketothiolase | Authors: | Janardan, N, Harijan, R.K, Keima, T.R, Wierenga, R, Murthy, M.R.N. | Deposit date: | 2015-06-11 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.162 Å) | Cite: | Structural characterization of a mitochondrial 3-ketoacyl-CoA (T1)-like thiolase from Mycobacterium smegmatis Acta Crystallogr.,Sect.D, 71, 2015
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7CW4
| Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579 | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL | Authors: | Hong, J, Kim, K.J. | Deposit date: | 2020-08-27 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579. Biochem.Biophys.Res.Commun., 533, 2020
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1DM3
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7CW5
| Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579 | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A | Authors: | Hong, J, Kim, K.J. | Deposit date: | 2020-08-27 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579. Biochem.Biophys.Res.Commun., 533, 2020
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1M4S
| Biosynthetic thiolase, Cys89 acetylated, unliganded form | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | Authors: | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | Deposit date: | 2002-07-03 | Release date: | 2002-11-29 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
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6PCA
| Crystal structure of beta-ketoadipyl-CoA thiolase | Descriptor: | ACETATE ION, Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, ... | Authors: | Sukritee, B, Panjikar, S. | Deposit date: | 2019-06-17 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase. J Struct Biol X, 4, 2020
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4XL4
| Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL | Authors: | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | Deposit date: | 2015-01-13 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum Nat Commun, 6, 2015
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1M1O
| Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA | Descriptor: | ACETOACETYL-COENZYME A, Acetyl-CoA acetyltransferase, SULFATE ION | Authors: | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | Deposit date: | 2002-06-20 | Release date: | 2002-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
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6PCB
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1M4T
| Biosynthetic thiolase, Cys89 butyrylated | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | Authors: | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | Deposit date: | 2002-07-03 | Release date: | 2002-11-29 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
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4XL2
| Crystal structure of oxidized form of thiolase from Clostridium acetobutylicum | Descriptor: | ACETATE ION, Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | Deposit date: | 2015-01-13 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum Nat Commun, 6, 2015
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1M3K
| biosynthetic thiolase, inactive C89A mutant | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | Authors: | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | Deposit date: | 2002-06-28 | Release date: | 2002-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
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2C7Z
| Plant enzyme crystal form II | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Leonard, G.A, Hunter, W.N. | Deposit date: | 2005-11-30 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation. J.Mol.Biol., 359, 2006
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2C7Y
| plant enzyme | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Germain, V, Bryce, J.H, Smith, S.M, Leonard, G.A, Hunter, W.N. | Deposit date: | 2005-11-30 | Release date: | 2006-05-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation. J.Mol.Biol., 359, 2006
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6PCC
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