2QLQ
 
 | | Crystal structure of SRC kinase domain with covalent inhibitor RL3 | | Descriptor: | (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, Proto-oncogene tyrosine-protein kinase Src | | Authors: | Michalczyk, A, Rode, H.B, Gruetter, C, Rauh, D. | | Deposit date: | 2007-07-13 | | Release date: | 2008-03-11 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR.
Bioorg.Med.Chem., 16, 2008
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2QLR
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2QLS
 | | crystal structure of hemoglobin from dog (Canis familiaris) at 3.5 Angstrom resolution | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Packianathan, C, Sundaresan, S, Palani, K, Neeelagandan, K, Ponnuswamy, M.N. | | Deposit date: | 2007-07-13 | | Release date: | 2008-07-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Purification, Crystallization and Crystal structure analysis of hemoglobin from Dog (Canis familiaris)
To be Published
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2QLT
 | | Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae | | Descriptor: | (DL)-glycerol-3-phosphatase 1, 1,2-ETHANEDIOL, CALCIUM ION, ... | | Authors: | Tan, K, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-13 | | Release date: | 2007-08-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p from Saccharomyces cerevisiae.
To be Published
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2QLU
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2QLV
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2QLW
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2QLX
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2QLY
 | | Crystral Structure of the N-terminal Subunit of Human Maltase-Glucoamylase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | Sim, L, Rose, D.R. | | Deposit date: | 2007-07-13 | | Release date: | 2008-01-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity
J.Mol.Biol., 375, 2008
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2QLZ
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2QM0
 | | Crystal structure of BES protein from Bacillus cereus | | Descriptor: | BES, SULFATE ION | | Authors: | Kim, Y, Maltseva, N, Zawadzka, A, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-13 | | Release date: | 2007-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Crystal Structure of BES from Bacillus cereus.
To be Published
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2QM1
 | | Crystal structure of glucokinase from Enterococcus faecalis | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Glucokinase, ... | | Authors: | Kim, Y, Joachimiak, G, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-13 | | Release date: | 2007-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Crystal Structure of Glucokinase from Enterococcus faecalis.
To be Published
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2QM2
 | | Putative HopJ type III effector protein from Vibrio parahaemolyticus | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, POTASSIUM ION, ... | | Authors: | Kim, Y, Chang, C, Volkart, L, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-13 | | Release date: | 2007-07-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal Structure of Putative HopJ type III Effector Protein from Vibrio parahaemolyticus.
To be Published
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2QM3
 | | Crystal structure of a predicted methyltransferase from Pyrococcus furiosus | | Descriptor: | ACETIC ACID, CALCIUM ION, Predicted methyltransferase | | Authors: | Cuff, M.E, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-13 | | Release date: | 2007-09-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The structure of a predicted methyltransferase from Pyrococcus furiosus.
TO BE PUBLISHED
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2QM4
 | | Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | | Descriptor: | Non-homologous end-joining factor 1 | | Authors: | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-12-11 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
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2QM6
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2QM7
 | | MeaB, A Bacterial Homolog of MMAA, Bound to GDP | | Descriptor: | GTPase/ATPase, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | | Authors: | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-08-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria.
J.Biol.Chem., 282, 2007
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2QM8
 | | MeaB, A Bacterial Homolog of MMAA, in the Nucleotide Free Form | | Descriptor: | GTPase/ATPase, PHOSPHATE ION | | Authors: | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-08-28 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria.
J.Biol.Chem., 282, 2007
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2QM9
 | | Troglitazone Bound to Fatty Acid Binding Protein 4 | | Descriptor: | (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, Fatty acid-binding protein, adipocyte, ... | | Authors: | Gillilan, R.E, Ayers, S.D, Noy, N. | | Deposit date: | 2007-07-14 | | Release date: | 2007-10-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structural Basis for Activation of Fatty Acid-binding Protein 4
J.Mol.Biol., 372, 2007
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2QMA
 | | Crystal structure of glutamate decarboxylase domain of diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase from Vibrio parahaemolyticus | | Descriptor: | 1,2-ETHANEDIOL, Diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase | | Authors: | Osipiuk, J, Sather, A, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-07-14 | | Release date: | 2007-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | X-ray crystal structure of glutamate decarboxylase domain of diaminobutyrate-pyruvate transaminase and L-2,4-diaminobutyrate decarboxylase from Vibrio parahaemolyticus.
To be Published
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2QMB
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2QMC
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2QMD
 | | Structure of BACE Bound to SCH722924 | | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2R)-2-[(2R,4R)-4-(BENZYLOXY)PYRROLIDIN-2-YL]-1-(3,5-DIFLUOROBENZYL)-2-HYDROXYETHYL]-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | | Authors: | Strickland, C.O, Iserloh, U. | | Deposit date: | 2007-07-16 | | Release date: | 2008-03-11 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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2QME
 | | Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1) | | Descriptor: | CRIB domain of the Serine/threonine-protein kinase PAK 1, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Ugochukwu, E, Yang, X, Elkins, J.M, Burgess-Brown, N, Bunkoczi, G, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-07-16 | | Release date: | 2007-08-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 1 (PAK1).
To be Published
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2QMF
 | | Structure of BACE Bound to SCH735310 | | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-[(2R,4R)-4-PHENOXYPYRROLIDIN-2-YL]ETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | | Authors: | Strickland, C.O, Iserloh, U. | | Deposit date: | 2007-07-16 | | Release date: | 2008-03-11 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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