5JOF
 
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8I93
 | | ACE2-B0AT1 complex bound with methionine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | | Deposit date: | 2023-02-06 | | Release date: | 2023-09-27 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1.
Cell Discov, 9, 2023
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5J9Y
 | | EGFR-T790M in complex with pyrazolopyrimidine inhibitor 1b | | Descriptor: | (R)-1-(3-(4-amino-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, Epidermal growth factor receptor | | Authors: | Becker, C, Engel, J, Rauh, D. | | Deposit date: | 2016-04-11 | | Release date: | 2016-08-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR.
Angew.Chem.Int.Ed.Engl., 55, 2016
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2I4P
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8ZG0
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9AVC
 | | Fis1 Structure Y38E mutation | | Descriptor: | Mitochondrial fission 1 protein | | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | | Deposit date: | 2024-03-01 | | Release date: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress.
Nat Commun, 16, 2025
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2I51
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5JA8
 | | Crystal structure of the HigB2 toxin in complex with Nb2 | | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Hadzi, S, Loris, R. | | Deposit date: | 2016-04-12 | | Release date: | 2017-04-05 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
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9AVD
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5JAF
 | | LeuT Na+-free Return State, C2 form at pH 5 | | Descriptor: | Transporter, octyl beta-D-glucopyranoside | | Authors: | Malinauskaite, L, Sahin, C, Said, S, Grouleff, J, Shahsavar, A, Bjerregaard, H, Noer, P, Severinsen, K, Boesen, T, Schiott, B, Sinning, S, Nissen, P. | | Deposit date: | 2016-04-12 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.021 Å) | | Cite: | A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.
Nat Commun, 7, 2016
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8I92
 | | ACE2-B0AT1 complex bound with glutamine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | | Deposit date: | 2023-02-06 | | Release date: | 2023-09-27 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1.
Cell Discov, 9, 2023
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6L1L
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2I5T
 | | Crystal Structure of hypothetical protein LOC79017 from Homo sapiens | | Descriptor: | Protein C7orf24 | | Authors: | Bae, E, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-08-25 | | Release date: | 2006-09-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal structure of Homo sapiens protein LOC79017.
Proteins, 70, 2008
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8ZEP
 | | Cryo-EM structure of Adr-2-Adbp-1-dsRBD2 complex | | Descriptor: | Adr-2-binding protein 1, Double-stranded RNA-specific adenosine deaminase adr-2, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Liu, Z.M, Mu, J.Q, Wu, C. | | Deposit date: | 2024-05-06 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Cryo-EM structure of Adr-2-Adbp-1-dsRBD2 complex
To Be Published
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8ZG3
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8ZH7
 | | Crystal structure of N-terminal domain of N-methyl-D-aspartate receptor subunit NR1 in complex with patient-derived antibody | | Descriptor: | Antibody #003-102 heavy chain, Antibody #003-102 light chain, Glutamate receptor ionotropic, ... | | Authors: | Nomura, N, Kumazaki, K, Amano, Y. | | Deposit date: | 2024-05-10 | | Release date: | 2025-05-14 | | Last modified: | 2025-07-02 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis.
Nat Commun, 16, 2025
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2I6Y
 | | Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI | | Descriptor: | Anthranilate synthase component I, putative | | Authors: | Zwahlen, J, Subramaniapillai, K, Zhou, R, Kisker, C, Tonge, P.J. | | Deposit date: | 2006-08-29 | | Release date: | 2007-06-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 46, 2007
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8ZBV
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2IBB
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8ZED
 | | Crystal structure of aldolase AtoB | | Descriptor: | AtoB aldolase, CALCIUM ION | | Authors: | Ma, K, Fan, A, Lin, W. | | Deposit date: | 2024-05-05 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Molecular Basis for the Catalytic Mechanism of the NTF2-like Aldolase in the Biosynthesis of Linear Tetracyclic Meroterpenoids
To Be Published
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8ZEO
 | | Cryo-EM structure of Adr-2-Adbp-1-dsRBD1 complex | | Descriptor: | Adr-2-binding protein 1, Double-stranded RNA-specific adenosine deaminase adr-2, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Liu, Z.M, Mu, J.Q, Wu, C. | | Deposit date: | 2024-05-06 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Cryo-EM structure of Adr-2-Adbp-1-dsRBD1 complex
To Be Published
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2I7D
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8ZG9
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5JGL
 | | Crystal structure of GtmA in complex with S-Adenosylmethionine | | Descriptor: | S-ADENOSYLMETHIONINE, SODIUM ION, UbiE/COQ5 family methyltransferase, ... | | Authors: | Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Doyle, S. | | Deposit date: | 2016-04-20 | | Release date: | 2017-03-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7, 2017
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2I89
 | | Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5 | | Descriptor: | Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N. | | Deposit date: | 2006-09-01 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5.
Biochemistry, 45, 2006
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